Navigation Links
Coronary calcium distribution tied to heart attack risk
Date:5/26/2008

OAK BROOK, Ill. A new calcium scoring method may better predict a persons risk of heart attack, according to a new multicenter study published in the June issue of the journal Radiology. Calcium coverage scoring takes into account not only the amount of calcified plaque build-up in the coronary arteries, but also its distribution.

Now we know that the location of the calcium in the arteries is particularly important in estimating a patients potential risk, said the studys lead author Elizabeth Brown, Sc.D., research assistant professor in the Department of Biostatistics at the University of Washington in Seattle.

Heart disease is the leading cause of death in the U.S. Each year, 700,000 Americans die of heart disease, according to the Centers for Disease Control and Prevention. The most common form of heart disease in the U.S. is coronary artery disease, which is caused by a build-up of calcific plaque in the coronary arteries leading to the heart. The current standard of coronary calcium measurement gauges only the amount of calcium present in the arteries, not its spatial distribution.

Currently, physicians only see the result in terms of an overall score designed to measure the amount of calcified plaque, Dr. Brown said. This new approach will provide physicians with a measure of the proportion of the arteries affected.

The Multi-Ethnic Study of Atherosclerosis (MESA) began in July 2000. The prospective study included 6,814 men and women between the ages of 45 and 84. The researchers compared CT image data for 3,252 participants with calcific plaque to data collected from 3,416 patients without calcific plaque. (Due to lack of sufficient CT image data, 146 additional MESA participants were excluded from this analysis.) A calcium coverage score was developed to estimate the percentage of coronary arteries affected by plaque.

The patients were then followed up for a median period of 41 months to determine if there was a relationship between the distribution of calcium shown in the CT images and the likelihood heart attack or other cardiac event.

The results showed that diabetes, hypertension and dyslipidemia (abnormal concentrations of lipids [fats] or lipoproteins in the blood) were highly associated with calcium coverage score. The study also found that the calcium coverage scorewhich takes into account the location of the calciumwas a better predictor of future cardiac events than currently used measures that gauge only the amount of calcium present. On average, compared to patients without diabetes, patients with diabetes had 44 percent more of their coronary arteries affected by plaque. A twofold increase in calcium coverage score indicated a 34 percent increase in risk of heart attack or other serious cardiac event and a 52 percent increase in the risk of any cardiac event.

Calcium coverage scoring has the potential to improve our estimate of a patients risk for adverse clinical outcomes, such as heart attacks or death, Dr. Brown said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. When statins arent enough: New trial drug points to better management of coronary heart disease
2. MAQUET Cardiovascular Launches HEARTSTRING III Proximal Seal System for Coronary Artery Bypass Graft Surgery
3. Extremely low dose CT coronary angiography shows promise in assessing cardiac function
4. Clopidogrel reloading worthwhile in acute coronary syndromes
5. New Drug Shows Promise in Use With Coronary Stents
6. Calcium Scans Help Predict Coronary Risk
7. Acute Coronary Events Drop After Italys Public Smoking Ban
8. Triglycerides Linked to Coronary Disease Risk
9. Acute coronary events decreased after public smoking ban in Italy
10. UMass Medical School study finds patients diagnosed with coronary heart disease continue poor diets
11. Cardicas C-Port Anastomosis Systems for Coronary Artery Bypass Graft Procedures to be Used to Train Cardiothoracic Surgeons at Society of Thoracic Surgeons (STS) University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... ... issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the ... several important health care topics including advance care planning, healthcare costs and patient ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
(Date:6/23/2016)... June 23, 2016  In a startling report released today, ... residents by lacking a comprehensive, proven plan to eliminate prescription opioid ... ranking of how states are tackling the worst drug crisis in ... states – Kentucky , New Mexico ... . Of the 28 failing states, three – ...
Breaking Medicine Technology: