Navigation Links
Coronary angiography may improve outcomes for cardiac arrest patients
Date:3/31/2009

PITTSBURGH, March 31 People who suffer cardiac arrests and then receive coronary angiography are twice as likely to survive without significant brain damage compared with those who don't have the procedure, according to a study by University of Pittsburgh School of Medicine researchers. The study, published in the May/June issue of the Journal of Intensive Care Medicine and now available online, showed that patient outcomes improved with coronary angiography, an imaging procedure that shows how blood flows through the heart, regardless of certain clinical and demographic factors that influenced who received the procedure.

"Given the low odds of survival about 6 percent for patients who suffer out-of-hospital cardiac arrests, it's important to understand which treatments might make a difference in these dismal outcomes," noted Jon C. Rittenberger, M.D., corresponding author of the study and an assistant professor in the Department of Emergency Medicine at the University of Pittsburgh. The importance of prompt coronary angiography is well-established for cardiac arrest patients presenting with certain types of heart problems, Dr. Rittenberger noted. "But our study, which shows that angiography is independently associated with good neurologic outcomes, suggests that clinicians should consider the procedure for all post-cardiac arrest patients," he added.

Coronary angiography uses a contrast dye and X-rays to see the blood vessels and chambers of the heart. The procedure is usually done in conjunction with catheterization, which involves threading a thin hollow tube through an artery and into the heart. Dye is injected into the catheter and highlights any blockages in blood flow, which are then visible by X-ray.

The researchers retrospectively analyzed the charts of 241 adult cardiac arrest patients who were treated at UPMC Presbyterian Hospital, part of the University of Pittsburgh Medical Center, between January 1, 2005, and December 31, 2007. Coronary artery disease was present in 52 percent of the patients, and the rate did not differ between those who received coronary angiography (40 percent of the group) and those who did not. Those findings are consistent with prior research showing that 60 to 80 percent of cardiac arrests are a result of cardiovascular disease.

Just over half of patients who received coronary angiography experienced a good clinical outcome defined as being discharged to home or to an acute rehabilitation facility compared to 24.8 percent of patients who do not have the procedure. Early angiography, performed within 24 hours of a patient's arrival, was not associated with improved survival when compared to having the procedure done later, but researchers noted that the small number of patients may have made it impossible to prove a difference.

"Coronary angiography appears to put patients on a more proactive path of care, which may lead to a better outcome," said Dr. Rittenberger. "As this study demonstrates, most of these cardiac arrest patients have heart disease, which is often something that we can fix. Many of the patients who get coronary angiography go on to get bypass surgery, a balloon pump, a defibrillator or other such aggressive treatments."

Rittenberger and his colleagues found no significant differences between those who received angiography and those who did not with respect to age, history of cardiac disease and use of therapeutic hypothermia, a procedure used to cool patients who remain comatose after resuscitation following cardiac arrest to prevent brain damage. However, patient sex, location of the arrest, the initial heart rhythm disturbance and certain coronary and neurologic abnormalities were among the predictors of who would receive angiography. Men who suffered cardiac arrests outside of the hospital were more likely to have the procedure. The researchers also found that coronary angiography was more likely to be performed on patients with better neurological status. However, with the use of therapeutic hypothermia, patients may not reveal their true neurological state for several days after the return of spontaneous blood circulation, they noted.


'/>"/>

Contact: Wendy Zellner
ZellnerWL@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Related medicine news :

1. Number of Revascularization Procedures, Related In-Hospital Mortality and Some Complications Decline, While Rates of Infection and Acute Respiratory Distress Syndrome (ARDS) Following Coronary Artery Bypass Graft (CABG) Surgery Increase
2. Despite Patent Expiries of Leading Therapies, New Product Launches Will Drive a $4.6 Billion Increase in the Coronary Heart Disease Market
3. Stent 4 Life: A campaign is launched to increase the use of primary PCI in acute coronary patients
4. Abbott Launches VOYAGER(TM) NC Coronary Balloon Catheter
5. Society for Womens Health Research and MITA Promote Greater Awareness of Medical Imaging to Diagnose Womens Coronary Artery Disease
6. Traditional risk assessment tools do not accurately predict coronary heart disease
7. New Research Estimates 1500 Lives Could Be Saved Annually if the Lowest Performing Hospitals for Coronary Artery Bypass Graft Surgery Performed as Well as Top-ranking Hospitals
8. Coronary CTA: Non-invasive, low cost alternative for intermediate risk patients
9. Large study illustrates cardiac CT can effectively assess coronary artery disease
10. Mentice VIST(TM) New and Enhanced Carotid and Coronary Training Modules Take Medical Simulation Training to the Next Level
11. Ricky Tomlinson Joins Lloydspharmacy Against Coronary Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... ... , ... Many families have long-term insurance that covers care for a family ... for care if the client has a cognitive impairment diagnosis. , “What this ... often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, owner ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Yisrayl Hawkins, Pastor ... that explains one of the most popular and least understood books in the Holy ... and puzzling descriptions that have baffled scholars for centuries. Many have tossed it off ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed ... consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has ... highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  Caris Life Sciences ® , ... the promise of precision medicine, today announced that St. ... Precision Oncology Alliance™ (POA) as its 17 th ... St. Jude Crosson Cancer Institute will help develop standards ... of tumor profiling, making cancer treatment more precise and ...
(Date:10/10/2017)... Calif. , Oct. 10, 2017  NDS received FDA 510(k) ... — a medical-grade battery-powered display stand specifically designed for endoscopy environments. ... transform technology into a clinical solution to support the improvement of ... Innovative Design ... Mobile Wireless Solution ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
Breaking Medicine Technology: