Navigation Links
Coronary Disease Might Toughen Up Heart

Mice with the ailment suffered less cardiac damage after injury, study finds

MONDAY, Oct. 1 (HealthDay News) -- Coronary artery disease may actually precondition the heart and make it more resistant to damage than hearts unaffected by the illness, a British study in mice suggests.

Researchers at the University of Bristol and the Bristol Heart Institute used mice that were genetically modified to be prone to fatty build-up in the coronary arteries. One group of these mice was fed a high-fat diet typical of Western nations, while the other group of mice was fed a normal rodent diet. The mice fed a high-fat diet developed coronary artery disease, while those fed the rodent diet did not.

The researchers then stopped and restarted the rodents' hearts -- mimicking the conditions used in heart bypass surgery.

They found that the hearts of the mice with coronary artery disease were less likely to be harmed than the hearts of healthy mice.

This suggests that coronary artery disease "preconditioned" the hearts -- they'd developed an innate protection against further damage, said the authors of the study, which is published in the October issue of the journal Critical Care Medicine.

The researchers noted that there's a common belief that in certain patients who survive a heart attack, the heart may have been naturally preconditioned against further damage.

This is something that surgeons and cardiologists may be able to exploit in order to protect the heart when treating people with coronary disease, suggested the team members, who are continuing their investigation into this internal heart protection mechanism.

More information

The American Academy of Family Physicians has more about coronary artery disease.

-- Robert Preidt

SOURCE: University of Bristol, news release, Sept, 30, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease
2. Coronary stent leads to complications
3. Coronary heart disease bids Adieu
4. Older Men Surviving Coronary Bypasses
5. The Benefits of abciximab with clopidogrel for percutaneous coronary intervention Questioned
6. The Link Between Oxidized Phospholipids And Coronary Artery Disease
7. Cigarette Smoking Leads To Development Of Type 2 Diabetes In Patients With Coronary Artery Disease
8. Erectile dysfunction: an early warning sign of clinically silent coronary artery disease?
9. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins
10. Effectiveness Of Drug-Releasing Coronary Stents
11. Children Are At The Risk Of Inheriting Coronary Disease
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... The OSHA Training ... Institute Education Center headquartered in Northern California, has issued an important reminder to ... their worksites. Employers with workers exposed to high temperatures should establish a ...
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their ... Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. , ... Pro X users can now reveal the media of their split screens with ...
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... its affiliation with Tennessee Counseling Association. This new relationship allows TherapySites ... Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... industry today announced its strategic partnership with Connance, a healthcare industry leader ... two companies’ proven, proprietary technology combine to provide health systems, hospitals and ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... technology to revolutionize the emergency ambulance transport experience for the millions of people ... how Uber has disrupted the taxi industry through the use of technology. Now, ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 One of ... has announced the formation of a new biotechnology company, Noxopharm Limited ... $6m in an IPO and to list on the ASX. ... candidate, NOX66, ready to enter a Phase 1 clinical study later ... designed to address one of the biggest problems facing cancer patients ...
(Date:6/26/2016)... DUBLIN , June 27, 2016 Jazz ... the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act ... proposed acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... 11:59 p.m. (Eastern Daylight Time). As previously ... entered into a definitive merger agreement under which Jazz ...
(Date:6/26/2016)... Ontario , June 27, 2016  VMS Rehab ... Company,s Board will take whatever measures required to build ... Company,s stock which is currently listed on the OTC ... Wexler, Company Chairman and CEO, "We are seeing an ... difficult to understand, not only by the Company, but ...
Breaking Medicine Technology: