Navigation Links
Cordex Pharma Files ATPace Formulation Patent
Date:3/4/2009

LA JOLLA, Calif., March 4 /PRNewswire-FirstCall/ -- Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that it has filed a formulation patent covering its lead product, ATPace.

ATPace is a stable liquid formulation of adenosine triposphate (ATP) for intravenous administration. ATPace is being developed as a therapeutic drug for the acute management of paroxysmal supraventricular tachycardia (PSVT) as well as a diagnostic test for the identification of patients with bradycardic (slow heart rate) syncope who may benefit from pacemaker therapy. Injectable formulations of ATP, similar to ATPace, have been approved and marketed in Europe for over 50 years as safe and efficacious pharmaceutical treatments for PSVT.

Cordex has recently announced the submission to the FDA of an amended Phase 3 clinical trial protocol with ATPace as an antiarrhythmic drug for the conversion of PSVT to normal sinus rhythm. The FDA is currently reviewing this protocol through the Special Protocol Assessment procedure.

A stable liquid formulation of ATP is a prerequisite for ATPace's marketing and clinical superiority over adenosine, the only approved competition in the U.S. The maintenance of intact ATP molecules in the solution is critical for the unique bradycardic effects of ATP, in particular its blockade of atrio-ventricular (AV) nodal conduction. Specifically, ATP is believed to have dual inhibitory action, one mediated by adenosine, the product of its rapid degradation in the blood vasculature by ecto-enzymes, and the other a rapid and potent ATP-triggered vagal reflex. The latter mechanism of action is believed to be responsible for its superior efficacy over adenosine, which does not trigger a vagal reflex in the heart. Physical vagal maneuvers aimed at enhancing vagal input to the heart, and thereby suppressing atrio-ventricular nodal conduction, have been clinically used to terminate tachycardia in certain cases.<
'/>"/>

SOURCE Cordex Pharma, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Cordex Pharma Submits to the FDA an Amended Special Protocol Assessment for ATPace
2. Cordex Pharma Sets Fourth Quarter 2008 Program Update Call
3. ViroPharma to Host Investor Teach-In Educational Symposium on Hereditary Angioedema
4. Ferring Pharmaceuticals Announces Immediate Availability of Degarelix for the Treatment of Advanced Prostate Cancer
5. CVS/pharmacy Offers Free Prescription History Just in Time for Tax Season
6. Frost & Sullivan Lauds OVATION Pharmaceuticals for Its Business Model and Ability to Sustain Growth
7. NovaBay Pharmaceuticals Announces New Preclinical Data to be Presented at the American Academy of Dermatology (AAD) 67th Annual Meeting
8. Levels of Trace Pharmaceuticals in Drinking Water Too Low to Impact Human Health According to Water Research Foundation Study
9. AUDIO from Medialink and Ortho-McNeil-Janssen Pharmaceuticals: Risks of Overusing Antibiotics
10. Pharmasset to Present at Two Upcoming Investor Conferences
11. Onyx Pharmaceuticals to Present at the Barclays Capital Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014Popular fiction that normalizes and glamorizes violence against ... be associated with a greater risk of potentially harmful ... new study are presented in the article " Fiction ... in Adolescent and Young Adult Females ," published in ... from Mary Ann Liebert, Inc., publishers . The ...
(Date:8/21/2014)... Individuals with schizophrenia often have trouble engaging in daily ... study from San Francisco State University suggests the reason ... effort required to complete tasks. , The research, detailed ... Journal of Abnormal Psychology , can assist health professionals ... help those patients function normally by breaking up larger, ...
(Date:8/21/2014)... August 21, 2014 Entries are now ... the only comprehensive national awards program totally dedicated to ... development and executive leadership. The entry deadline is Oct. ... Real Estate Insights™, the first and only national magazine ... and investment. , “We launched the HREI Insights Awards ...
(Date:8/21/2014)... York, New York (PRWEB) August 21, 2014 ... Medical Cannabis Network that a company located in Massachusetts ... be the only marijuana patient verification system ... to welcome this new entity to our growing and ... to our belief that these claims are inaccurate. ...
(Date:8/21/2014)... Steven Reinberg HealthDay Reporter ... shows promise in treating respiratory syncytial virus (RSV), a leading ... finally making major progress in being able to treat human ... viral pneumonia, second only to influenza virus," said study author ... of Tennessee College of Medicine in Memphis. "There ...
Breaking Medicine News(10 mins):Health News:Women's health and Fifty Shades: Increased risks for young adult readers? 2Health News:Difficulty assessing effort drives motivation deficits in schizophrenia, study finds 2Health News:Entries Open for 2014 HREI Insights Awards™ 2Health News:Entries Open for 2014 HREI Insights Awards™ 3Health News:Entries Open for 2014 HREI Insights Awards™ 4Health News:MarijuanaDoctors.com Responds to Massachusetts Company's Claim 2Health News:New Drug May Fight Serious Respiratory Virus in Infants 2Health News:New Drug May Fight Serious Respiratory Virus in Infants 3
... Denmark, Thursday 11 June 2009: Nulliparous women (those who ... chronic arthritides (including ankylosing spondylitis, psoriatic arthritis and rheumatoid ... women (those who have given birth to children), according ... the Annual Congress of the European League Against Rheumatism ...
... As Congress prepares to debate a major overhaul of the ... support of several proposals to expand coverage that have been ... Health Confidence Survey released today. But attitudes could change as ... , Between 68 percent and 88 percent of Americans either ...
... SYK ) announced today that it will host a conference ... to discuss the Company,s operating results for the quarter ended June ... quarter ended June 30, 2009 will be released at 4:00 p.m. ... dial 866-700-0133 (domestic) or 617-213-8831 (international) and ...
... in whether women decide to go for cancer screening or not, ... wrongly assume that they will ask for information if they want ... study published in the June issue of the UK-based Journal ... and Dr Stephanie Preston reviewed 19 studies that between them explored ...
... Quality of Life of Injured Veterans , , ... by Kessler Foundation Research Center published in Brain ... Injury Association, uncovered the possible cause of cognitive fatigue ... fatigue has been shown to be one of the ...
... at August Luncheon , , DENVER, June 11 ... of kidney care services for those diagnosed with chronic kidney ... the Los Angeles Business Journal ,s 2009 "Best Places ... 67 companies chosen for their impact on the region,s economy, ...
Cached Medicine News:Health News:Diagnosis of arthritis 5 years earlier in childless women compared to those with children 2Health News:12th Annual Health Confidence Survey: Americans Show Support for Several Health Coverage Options, But Their Views Could Change as More Details Emerge 2Health News:12th Annual Health Confidence Survey: Americans Show Support for Several Health Coverage Options, But Their Views Could Change as More Details Emerge 3Health News:Stryker to Host Conference Call on July 21, 2009 2Health News:Cancer screening fear is fueled by lack of information says review covering nearly 6,000 women 2Health News:Kessler Foundation Research Center Study Provides Insight into One of the Most Challenging Symptoms Following a Traumatic Brain Injury 2Health News:Kessler Foundation Research Center Study Provides Insight into One of the Most Challenging Symptoms Following a Traumatic Brain Injury 3Health News:DaVita Named to List of 'Best Places to Work in Los Angeles' by the Los Angeles Business Journal 2
(Date:8/21/2014)... , Aug. 21, 2014 /CNW/ - Eisai Limited is ... introduction of the first-of-its-kind comic book available in ... has been designed specifically to educate children and their parents ... Canada affecting more than 300,000 Canadians. Eisai is ... care (hhc) , in which the patient is central – ...
(Date:8/21/2014)... Germany , Aug. 21, 2014  IBM (NYSE: ... Elektronen-Synchrotron ( DESY ), a leading national research center ... management and storage of massive volumes of x-ray data. ... based on IBM software defined technology can handle more ... performance and help scientists worldwide gain faster insights into ...
(Date:8/21/2014)... August 21, 2014 BreedIT ... Ltd., the exclusive worldwide license holder and distributor ... breeders and researchers, today is pleased to announce ... with Seach Ltd, a leading Israeli medical Cannabis ... and develop new breeds of medical Cannabis to ...
Breaking Medicine Technology:Eisai Pleased to Support Canadian Epilepsy Alliance Comic Book that Teaches Children About Epilepsy 2DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 4
... Sept. 2, 2011 SimonMed and Cox Business have ... called tomosynthesis available to patients in the Valley and ... traditional digital mammogram. This is the first dedicated outpatient ... offered at SimonMed,s office in Scottsdale. Sub-specialty ...
... Pharmaceuticals International, Inc. (NYSE: VRX ) (TSX: VRX) ... will be participating at the following conferences: ... a presentation at the Bank of America Merrill Lynch Global ... at 10:35 a.m. BT (5:35 a.m. ET). ...
Cached Medicine Technology:SimonMed and Cox Business Bring Breast Tomosynthesis to Arizona 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: