Navigation Links
Cord blood effective alternative to matched donor stem cells for kids with rare disorder
Date:3/14/2013

ared the safety and efficacy of different stem cell and donor sources among a large group of patients to determine which may be the ideal transplant source."

With this aim, Dr. Boelens and a team of investigators conducted a retrospective analysis analyzing outcomes of HS patients treated with HCT in centers affiliated with the European Group for Blood and Marrow Transplantation (EBMT), Eurocord, and the Center for International Blood and Marrow Transplant Research (CIBMTR). A total of 258 infants and children with HS (ranging from 2 months to 18 years, with a median age of 16 months at transplant) who received an HCT between 1995 and 2007 were selected for analysis based upon certain criteria: a confirmed diagnosis of HS; a transplant of cells from a matched sibling donor (MSD), a matched or mismatched unrelated donor (UD), or cells from a single, unrelated cord blood (UCB) unit; and pre-transplant treatment containing a high dose of chemotherapy to help prevent their immune systems from rejecting donated cells.

Nearly half of the children evaluated in the study (45%) had received transplants of unrelated cord blood (81% of which was from mismatched donors) with the others receiving transplants of bone marrow stem cells from unrelated donors or matched sibling donors. All the patients received pre-transplant high-dose chemotherapy, and 19 percent had previously received intravenous enzyme replacement therapy with lysosomal α-L-iduronidase. Taking into consideration stem cell source and pre-transplant conditioning, the team compared the rates of overall survival (OS), event-free survival (EFS), engraftment (the degree to which transplanted donor cells were able to reproduce into new cells) or graft failure, or death.

The team noted encouraging survival rates among the children with HS who had received an HCT, regardless of source, with 5-year estimated OS and EFS at 74 percent and 63 percent, respectively. Importantly, EFS rates were
'/>"/>

Contact: Andrea Slesinski
aslesinski@hematology.org
American Society of Hematology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Infection Might Raise Blood Clot Risk for Older Adults: Study
2. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
3. Common Blood Pressure Drug Safe for Heart Failure: Study
4. Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA
5. High Blood Pressure May Be Especially Lethal for Blacks
6. Changes in gene expression may help explain high blood pressure in pregnancy
7. Researchers Develop Blood Test for Depression
8. Naturopathic care can improve blood sugar, mood in diabetes
9. Diabetes Groups Issue New Guidelines on Blood Sugar
10. Exercise May Help Patients With High Blood Pressure Live Longer
11. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... August 22, 2014 Today, Zane Benefits, ... guide on Account-Based Health Plans. , According to Zane ... a strategy to lower the cost of healthcare without ... medical spending accounts, however, can be confusing. , The ... learn the four main types of ABHPs. It also ...
(Date:8/22/2014)... This report studies the "Sample Preparation Market by ... Kits (Isolation, Purification), By Application (Genomics, Proteomics), by ... 2018" This market was valued at $4,254.8 million ... a CAGR of 5.9% from 2013 to 2018, ... 98 market data Tables and 23 Figures spread ...
(Date:8/22/2014)... Recently, iFitDress.com, a well-known wedding dress manufacturer and ... wedding gowns . In addition to this, the company’s ... are provided with low shipping fees. , He ... new wedding gowns. In our online store, there are ... choose from. What’s more, all of them are extremely ...
(Date:8/22/2014)... 2014 (HealthDay News) -- Many Americans know little about how ... of an outbreak in the United States, a new survey ... worried that there will be a major Ebola outbreak in ... an immediate family member will get sick with the deadly ... School of Public Health poll. However, those opinions don,t ...
(Date:8/22/2014)... NV (PRWEB) August 22, 2014 Mi40x ... uses university-proven research to show people how they can use ... muscle in only a matter of weeks has caught the ... “Ben Pakulski is one of the most well-known bodybuilders in ... the body he has today, that in itself is a ...
Breaking Medicine News(10 mins):Health News:Sample Preparation Market by Product and Application Worth $5,672 Million by 2018 - New Research Report by MarketsandMarkets 2Health News:Sample Preparation Market by Product and Application Worth $5,672 Million by 2018 - New Research Report by MarketsandMarkets 3Health News:Sample Preparation Market by Product and Application Worth $5,672 Million by 2018 - New Research Report by MarketsandMarkets 4Health News:Discounted Wedding Gowns For Sale At Leading Online Shop iFitDress.com 2Health News:Many Americans Harbor Unfounded Fears About Ebola Outbreak: Survey 2Health News:Mi40x: Review Exposes Ben Pakulski’s Guide to Packing on Lean Muscle Fast 2
... a medical device company focused on the treatment of ... Chief,Executive Officer, and Gregory J. Tibbitts, Chief Financial Officer, ... Growth Conference in,New York, NY on Thursday, September 20, ... A live Web cast and recording of the ...
... Sept. 17 John Brooke, General Manager of,Billian,s ... speaking at Dreamforce ,07 Global Gathering, Salesforce.com,s 5th,Annual ... week. Dreamforce is the ultimate gathering of ... base of Salesforce and AppExchance,users spanning industries, roles ...
... commonly used measure for pain screening may only be modestly ... Medicine and the University of North Carolina. In a study ... General Internal Medicine, they evaluate the usefulness of a scale ... pain from 0 (no pain) to 10 (worst pain). ...
... Opening of the 62nd United Nations General Assembly Tomorrow, September ... ... people dying,of hunger every day and governments failing to meet their millennium,commitment to ... food and hunger to play a,central role "on the table" of the 62nd ...
... 17, 2007) Contrary to concerns that restricting work ... patient care or the residents education, a study in ... College of Surgeons found that limiting work hours does ... addition, the study found that the new model improved ...
... Association,Inc. ("SMART"), announced today that it has become ... a not-for-profit, multi-industry,association working to stimulate the understanding, ... The Smart Card Alliance is the sole ... on the impact and value of Smart,cards in ...
Cached Medicine News:Health News:CryoCor to Present at Maxim Group First Annual Growth Conference in New York 2Health News:Billian's HealthDATA GM Speaking on Dreamforce 07 Panel 2Health News:Rating your pain from 0 to 10 might not help your doctor 2Health News:HungerFREE Campaign Tells UN: 'Put food on the table' 2Health News:Study finds limiting work hours for surgical residents enhances training 2Health News:SMART Association Becomes 'Healthcare Council Member' of Smart Card Alliance 2
(Date:8/22/2014)... Aug. 22, 2014  As the Medical Affairs, role ... leaders in this area are exploring methods to develop ... Medical Affairs Consortium at Best Practices, LLC is designed ... insights about the key challenges they face. The consortium ... through three virtual roundtable discussions where leaders discuss key ...
(Date:8/22/2014)...  Dr. Mark Rasak , MD is recognized ... Award in the field of Medicine as a result ... Dr. Rasak has over 15 years of ... the business; overseeing the daily operations; interventional cardiology; complex ... addition, he is an honored Fellow of the American ...
(Date:8/22/2014)... --  Zacks Equity Research highlights Epizyme (Nasdaq: EPZM - ... (Nasdaq: PNRA - Free Report ) as the Bear of ... Therapeutics (Nasdaq: FOLD - Free Report ), Sanofi (NYSE: ... Free Report ). Here is a synopsis of all ... The biotech bull market is far from over ...
Breaking Medicine Technology:Best Practices' Medical Affairs Consortium Survey Has Achieved Strong Participation 2Dr. Mark Rasak, MD is recognized by Continental Who's Who with the Diamond Lifetime Achievement Award 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 3Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 4Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 5Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 6
... Althea Technologies, Inc., a leading provider of development ... its inaugural Health and Wellness Fair today. The fair ... daily activities to promote physical and mental health amongst ... encouraged to participate in daily challenges and talks. Today,s ...
... 2011 Delcath Systems, Inc. (NASDAQ: DCTH ) ... Life Sciences Management Access Conference on Tuesday, August 16, 2011 ... Financial Officer, will provide an overview of the Company,s business ... this conference is by invitation only. Delcath will offer a ...
Cached Medicine Technology:Althea Technologies Hosts Health and Wellness Week 2Delcath to Present at the Wedbush 2011 Life Sciences Conference on August 16, 2011 2Delcath to Present at the Wedbush 2011 Life Sciences Conference on August 16, 2011 3
... is a monoclonal antibody based ... confirmatory identification of Neisseria gonorrhoeae. ... isolated, viable or fresh cultures. ... two minute rotation, a positive ...
Rapid Test Kit...
... The InTray™ GC is a ... detection of both Neisseria gonorrhoeae and ... a long shelf life and is ... system. Simply inoculate, incubate and ...
OneStep Strip Style Gonorrhea Test is a rapid direct binding test for the visual detection of gonorrhea antigen, in the secretory specimen and urine from urogenital system, as an aid in the diagnosis...
Medicine Products: