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'Cool' New Treatment for Hot Flashes in Breast Cancer Survivors
Date:5/14/2008

on healthy menopausal women that the stellate ganglion block can effectively 'shut off' these troubling symptoms. Since these symptoms are generally more severe in women who have undergone breast cancer treatment, the block is a significant arsenal in helping estrogen-depleted women feel better with few or no side effects."

Women on hormone replacement therapy were excluded from the study. The 13 study patients were 30 to 70 years of age (mean age, 53 years). Four of the 13 patients had been diagnosed with Stage 0 breast cancer (or infiltrating ductal carcinoma in situ, the earliest, and noninvasive, cancer stage), 4 had Stage 1 cancer, 4 had Stage 2, and 1 had Stage 3. Using two standardized measures, each patient recorded the severity and intensity of her hot flashes and the number of night awakenings for 1 week before the procedure and weekly for 12 weeks postprocedure. The investigators applied a statistically-sound estimating equation to analyze the number of hot flashes and night awakenings over time.

If the effect of the stellate ganglion block on hot flashes and night awakenings did not last throughout the 12-week study period, the block was repeated. The decision to repeat the block was made by the patient if she felt her symptoms were returning. (Multiple blocks have been used for decades without increased risk.) Of the 13 women, 5 had only 1 stellate ganglion block and 8 women had 2 blocks. Women who had 2 blocks generally reported more lasting relief of symptoms than after the first procedure.

The total number of hot flashes decreased from a mean of 79.4 per week before the procedure to a mean of 49.9 per week during the first 2 weeks after the treatment. After 2 weeks, the total number of hot flashes continued to decline and stabilized at 8.1 per week from weeks 3 through 12. The severity of the hot flashes similarly decreased, with the most dramatic drop-off in severity occurring within 1 day to 1 week after treatment; the rate of
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SOURCE DAVIS MEDPR, Inc.
Copyright©2008 PR Newswire.
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