Navigation Links
Control of herpes symptoms does not reduce HIV transmission, international study found
Date:1/25/2010

INDIANAPOLIS Research from a five-year international clinical study shows that acyclovir, a commonly prescribed drug used to suppress symptoms of the herpes virus, does not affect HIV transmission by people with both viruses.

The study, conducted by the Partners in Prevention HSV/HIV Transmission Study, was released by the New England Journal of Medicine in its online edition Jan. 20 and will follow in the print edition Feb. 4.

The largest risk group worldwide, but particularly in Africa and Asia, for contracting HIV is stable, heterosexual couples where only one partner is infected. Among those infected, about 90 percent also have a herpes simplex virus-2 (HSV-2), the most common cause of genital herpes, said study co-author Kenneth H. Fife, M.D., Ph.D., professor of medicine in the Division of Infectious Diseases at the Indiana University School of Medicine.

"Logic indicated that outbreaks of HSV-2 sores could enhance the transmission of HIV," said Dr. Fife. "This is the first comprehensive study to look at the potential for reducing the transmission of HIV through treatment of the herpes virus."

Multiple studies have shown that frequent genital herpes recurrences increase the amount of HIV in the blood and genital tract. It is known that HIV virus is shed through genital herpes ulcers and people with those ulcers transmit HIV to other more efficiently.

Five preliminary studies showed that it is possible to decrease the amount of HIV in the blood and genital tract through treatment to suppress HSV-2. However, those studies did not measure whether there also was a reduction in HIV transmission.

The study found that acyclovir reduced the occurrence of HSV-2 genital ulcers by 73 percent and thus the amount of HIV present in the blood and genital tract decreased twofold.

In spite of the reduction of HIV present in blood levels, the researchers found there was no significant difference in the transmission of HIV. Laboratory testing showed there were 41 infections in the group taking acyclovir and 43 in the placebo group.


'/>"/>

Contact: Mary L. Hardin
mhardin@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert

Related medicine news :

1. Chromatin remodeling complex connected to DNA damage control
2. More than two-thirds of sexually active NYC youth use condoms, but other forms of birth control lag
3. New Asthma Guidelines Stress Disease Control
4. UI nursing researcher to study post-operative pain control
5. Uncontrolled Blood Pressure Highest Among Hispanics, Prompting New Hypertension Project in San Antonio
6. Hispanics hypertension better controlled with equal access to care
7. Detroit Metro Tower Air Traffic Controllers File Lawsuit Alleging Improper Mold Removal and Health Effects
8. Maternal depression and controlling behavior associated with increased stress response in infants
9. New Website Helps Women Be Fit, Sexy and in Control!
10. Controlling for size may also prevent cancer
11. Cancer control in Europe works; now it is time to extend it to poorer countries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... SC (PRWEB) , ... May 27, 2016 , ... ... a line of classic American timber frame barn kits, which can be found on ... are inspired by historic American barn plans, and they highlight the craftsmanship of timber ...
(Date:5/27/2016)... NY (PRWEB) , ... May 27, 2016 , ... An ... returns for a third time to shed lights on the variety of topics detailing ... inspirational stories, “Nurse Appreciation” tackles why this career has gone from being in a ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... this installment is bolstered by inspiring human-interest stories, courtesy of awareness-driven celebrities and ... the industry, from leading advocates, associations and industry leaders such as Bioness. ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses ... human interest stories, courtesy of leaders in the nursing and health care industry. ... from leading advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett ...
(Date:5/27/2016)... ... May 27, 2016 , ... ... in the pharmaceutical, medical and food industries. Aside from its GMP accreditation, Validation ... providing proof of successfully certified products, services and staff. , Validation Center is ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... Mass. , May 24, 2016  NxStage Medical, ... technology company focused on advancing renal care, today announced ... plans to participate in the following schedule of investor ... be made available at http://ir.nxstage.com/ . ... Jefferies Healthcare Conference NY, NY           Friday, June ...
(Date:5/24/2016)... 24, 2016  Joe Marziani has joined VMS BioMarketing as senior vice president of ... In his new role, Marziani will lead the company,s business development and sales team, ... outcomes. Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... , May 24, 2016 ... doble terapia del mundo, introduce catéteres para la ... OrbusNeich, una compañía global especializada en el ... ha expandido su cartera incluyendo productos para tratar ... y Scoreflex™ PTA son los dispositivos de primera ...
Breaking Medicine Technology: