Navigation Links
Contrary to popular belief, not all cases of chronic pancreatitis are alcohol-induced
Date:3/11/2011

The relative rate of alcohol-related chronic pancreatitis (CP) is lower when compared to other causes, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute. Patients with no identifiable cause for their disease as well as those with non-alcohol-related causes represent an unexpectedly large subgroup, particularly among women.

"One of the more remarkable observations is that in more than 50 percent of patients, alcohol was not considered as the causative factor of chronic pancreatitis," said Gregory A. Cot, MD, MS, of Indiana University School of Medicine and lead author of this study. "Future analyses will likely identify previously unrecognized genetic factors and/or interaction between genes and environmental factors as potential explanations of disease development. In the meantime, the era of dismissing all cases of chronic pancreatitis as alcohol-induced has undoubtedly come to a close."

Doctors studied data from patients with CP and controls enrolled in the North American Pancreatitis Study, which was designed to further the understanding of the role of gene-environment interactions in patients with recurrent acute pancreatitis and CP. Among the groups, 44.5 percent of patients had CP due to alcohol consumption, 26.9 percent had non-alcohol related CP, and 28.6 percent had CP of unknown cause.

Doctors observed that the current etiologic profile of CP patients evaluated at U.S. referral centers is quite different from historical data. Although alcohol remains the most common cause, a larger fraction of patients was considered to have non-alcoholic etiologies, and in more than a quarter of patients, no identifiable cause of disease (i.e., idiopathic CP) was apparent. Among the risk factors assessed, smoking was independently associated with idiopathic CP.

Pancreatitis usually begins as a sudden attack. When the pancreas becomes inflamed, its digestive enzymes attack the tissue that produces them. One of these enzymes, called trypsin, can cause tissue damage and bleeding, which may cause the pancreas tissue cells and blood vessels to swell. In some cases, the attacks may recur frequently over time, which is known as CP. The onset of CP remains hard to define. This condition can be caused by alcohol, smoking and a multitude of other factors.


'/>"/>

Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related medicine news :

1. University of Pennsylvania: Contrary to popular models, sugar is not burned by self-control tasks
2. Popular Baby Media May Not Actually Advance Learning
3. Popular drugs for common male health problems can affect their sexual health
4. Popular Bone Drugs Linked to Reduced Colon Cancer Risk
5. Bullying May Accompany Drive to Be Popular
6. Zebrafish popular with researchers
7. Tanning Beds Still Popular Despite Skin Cancer Risk
8. Popular Mechanics breakthrough awardees announced
9. Popular prostate cancer treatment associated with bone decay
10. New guideline finds no evidence for a popular back procedure
11. Expert Panel Links Popular Bone Drugs to Rare Fracture
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... Ongoing news of the ravages of ... (ALCA) to conduct a survey that takes a closer look at cases of TBI ... prevalence and causes of TBI among the aging population, and identifies the challenges associated ...
(Date:2/10/2016)... ... , ... Gout is like no other joint pain. It strikes suddenly, like ... swelling and redness. It is triggered by the crystallization of uric acid within the ... susceptible, according to the February 2016 issue of Harvard Men's Health Watch. , The ...
(Date:2/10/2016)... ... ... AHRA: The Association for Medical Imaging Management announced today ... as keynote speaker at the organization’s 2016 Spring Conference. Fox’s topic, Lead with ... with their own organizational staff and leadership. , “I am so excited ...
(Date:2/10/2016)... ... 10, 2016 , ... A national ergonomics pioneer , ... event March 9-11, 2016. Hosted by Ohio's Bureau of Worker's Compensation, the expo ... longest running and largest worker's compensation event in Ohio, organizers of the safety ...
(Date:2/10/2016)... Middleboro, MA (PRWEB) , ... February 10, 2016 ... ... of their revolutionary, biocompatible columns and accessories. These PEEK-lined stainless steel (PLS) columns ... to provide a solution that ensures the integrity of biological samples while operating ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... 10, 2016 Antibacterial Drugs Market - ... - 2023 ", reveals that the global antibacterial drugs market ... to 2023 owing to patent expiries of blockbuster drugs. Even ... during the forecast period, the value is anticipated to decline ... --> Antibacterial Drugs Market - Global Industry Analysis, ...
(Date:2/10/2016)... 10, 2016  Silicon Biosystems Menarini Inc., a ... help uncover the biological complexities of disease at ... developer of innovative technologies for genomics research, today ... at enabling translational researchers to obtain high-quality sequencing ... tumor and normal cells in an optimized and ...
(Date:2/10/2016)... PUNE, India , February 10, 2016 ... to a new market research report "Pharmaceutical Packaging Equipment ... Packaging, Wrapping, Labeling & Serialization), by Product Type (Tablet, ... to 2020", published by MarketsandMarkets, studies the global market during ... is expected to grow at a CAGR of 6.9% ...
Breaking Medicine Technology: