merican Heart Association and a professor of cardiology at the University of California, Los Angeles, said the study findings may be an example of the "obesity paradox." This theory holds that obesity is a well-established risk factor for developing hypertension, heart disease and heart failure, while "among individuals with established hypertension, coronary heart disease, and heart failure, obesity has been unexpectedly associated with lower cardiovascular event rates and mortality."
These new findings suggest that an individual's BMI should be considered when selecting anti-hypertensive medications, he said.
"Treatment with calcium channel blockers appears preferable to treatment with diuretics in non-obese men and women with hypertension," Fonarow said.
The study was funded by Novartis Pharmaceuticals, maker of Lotensin.
For more information on high blood pressure, visit the American Heart Association.
SOURCES: Michael Weber, M.D., Downstate Medical Center, State University of New York, New York City; Franz Messerli, M.D., cardiologist, and director, hypertension program, St Luke's-Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York City; Gregg Fonarow, M.D., spokesman, American Heart Association, and professor, cardiology, University of California, Los Angeles; Dec. 6, 2012, The Lancet, online
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