Common Data Elements in Radiologic Imaging of Traumatic Brain Injury
Ann-Christine Duhaime, MD, Alisa D. Gean, MD, E. Mark Haacke, PhD, Ramona Hicks, PhD, Max Wintermark, MD, Pratik Mukherjee, MD, PhD, David Brody, MD, Lawrence Latour, PhD, Gerard Riedy, MD, Common Data Elements Neuroimaging Working Group Members, Pediatric Working Group Members
Radiologic brain imaging is the most useful means of visualizing and categorizing the location, nature, and degree of damage to the central nervous system sustained by patients with traumatic brain injury (TBI). In addition to determining acute patient management and prognosis, imaging is crucial for the characterization and classification of injuries for natural history studies and clinical trials.
Common Data Elements for Traumatic Brain Injury: Recommendations from the Biospecimens and Biomarkers Working Group
Geoffrey T. Manley, PhD, Ramon Diaz-Arrastia, MD, PhD, Mary Brophy, MD, MPH, Doortje Engel, MD, PhD, Clay Goodman, MD, Katrina Gwinn, MD, Timothy D. Veenstra, PhD, Geoffrey Ling, MD, PhD, Andrew K. Ottens, PhD, Frank Tortella, PhD, Ronald L. Hayes, PhD
Human biospecimens and biofluids represent an important resource from which molecular data can be generated to detect and classify injury and to identify molecular mechanisms and therapeutic targets. To date, there has been considerable variability in biospecimen and biofluid collection, storage, and processing in traumatic brain injury (TBI) studies. To realize the full potential of this important resource, standardization and adoption of best practice guidelines are required to insure the quality and consistency of these specimens. With the adoption of these standards and best practices, future investigators will be able to obtain da
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Elsevier Health Sciences