Navigation Links
Cone snails and plants used to develop oral drug for pain
Date:4/16/2008

Molecules from cone snail venom and African plants are being used by Queensland researchers as a blueprint to develop an oral drug to treat chronic pain.

Professor David Craik and Dr Richard Clark from the Institute for Molecular Bioscience have received $218,275 from the National Health and Medical Research Council (NHMRC) to aid in translating their research into a product available for Australians to use.

Studies on the molecule they have developed have shown that it is effective in relieving neuropathic pain in animals.

Neuropathic pain is one of the most severe forms of chronic pain, and very difficult to treat, Dr Clark said.

Regular pain occurs when the nervous system is stimulated by, for example, an injury, whereas neuropathic pain occurs when the nervous system itself is damaged.

Current treatments in neuropathic pain only provide meaningful relief for one in three patients, and all of the current market-leading drugs have serious side effects, as well as taking up to three weeks to begin to take effect.

Peptides (small proteins) from cone snail venom have attracted recent attention from scientists, as they can target receptors with a high degree of accuracy, thus eliminating severe side effects.

But peptides also degrade rapidly in the body. Professor Craik and Dr Clark have overcome this problem by engineering a circular peptide, using a circular protein backbone discovered by Professor Craik and found in plants such as violets.

The NHMRC Development grant will allow the researchers to further test their molecule to fully establish its therapeutic potential.

Successful outcomes from this project will provide additional confirmation of the suitability of our molecule as a treatment for neuropathic pain, Dr Clark said.

Armed with these data, we will be able to secure a commercial partner and develop this molecule into a tablet for sufferers of chronic pain.


'/>"/>

Contact: Bronwyn Adams
communications@uq.edu.au
61-733-462-134
Research Australia
Source:Eurekalert

Related medicine news :

1. New Technology Promises Safer Organ Transplants and Soft Tissue Surgeries
2. Lung transplants in cystic fibrosis patients with life-threatening bacteria sparks debate at ISHLT
3. Parkinsons Disrupts Stem Cell Therapy Transplants
4. Lung transplants not dangerous for children with cystic fibrosis, after all
5. Study shows lifetime effects of pediatric liver transplants
6. ABC and NMDP Partner to Meet Growing Need for Stem Cell and Cord Blood Transplants, Assure Funding for Cord Blood Network, Encourage Minority Donor Recruitment
7. New technique improves outcome for living donor liver transplants
8. New Interventional Radiology Treatment Shows Hope for People With Complications from Bone Marrow, Stem Cell Transplants
9. NIH grant to Emory and pediatric partners aims to improve kidney transplants for children
10. Boston Scientific Announces First European Implants of New Devices to Treat Heart Failure and Sudden Cardiac Death
11. Small-Diameter Dental Implants Increasingly Popular In the US
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Los Angeles, CA (PRWEB) , ... May 03, 2016 , ... ... Massage Chair with its user friendly Samsung tablet and exclusive Smart Application. The ... truly unbeatable massage. Starting each massage with a customized user profile and specialized massage ...
(Date:5/3/2016)... ... 03, 2016 , ... Intrigma, the leading provider of vital ... expanding its use of Intrigma’s cloud-based physician scheduling solution, Efficient Scheduler (a part ... The Portland, Oregon based health system conducted a one-year pilot of the Efficient ...
(Date:5/3/2016)... ... May 03, 2016 , ... Octo ... solutions and digital consulting services to the federal government, has been awarded a ... / Indefinite Quantity (ID/IQ) contract in support of the U.S. Army Program Executive ...
(Date:5/3/2016)... CA (PRWEB) , ... May 03, 2016 , ... ... a special type of surgical procedure that can be used to diagnose and treat ... instruments can be inserted. These instruments include a special lighting system and lens that ...
(Date:5/3/2016)... ... 2016 , ... Branches, Inc. is proud to have been selected as a ... in South Miami. Macy’s is a wonderful community partner and has helped to support ... mentoring, enrichment and academic support to elementary students 5 days a week. Summer Shade, ...
Breaking Medicine News(10 mins):
(Date:5/2/2016)... May 2, 2016  Deerfield announced today it ... Graybug Vision, Inc. Graybug Vision is an early ... may transform care for ocular diseases including wet ... technology was first developed at Johns Hopkins University ... venture. Graybug Vision is developing ...
(Date:5/2/2016)... , May 2, 2016 ... to reach USD 11.1 billion by 2024, according ... Research, Inc. Major drivers of the sonography market ... areas and government recommendations for periodic ultrasound screenings ...      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) ...
(Date:4/29/2016)... New Jersey , April 29, 2016 /PRNewswire/ ... Software Suite for Life Sciences, Product Development Capabilities ... Global Life Science Customer Base . ... solutions provider, today announced the acquisition of Skura ... a global leader in adaptive sales enablement technology ...
Breaking Medicine Technology: