Navigation Links
Cone snails and plants used to develop oral drug for pain
Date:4/16/2008

Molecules from cone snail venom and African plants are being used by Queensland researchers as a blueprint to develop an oral drug to treat chronic pain.

Professor David Craik and Dr Richard Clark from the Institute for Molecular Bioscience have received $218,275 from the National Health and Medical Research Council (NHMRC) to aid in translating their research into a product available for Australians to use.

Studies on the molecule they have developed have shown that it is effective in relieving neuropathic pain in animals.

Neuropathic pain is one of the most severe forms of chronic pain, and very difficult to treat, Dr Clark said.

Regular pain occurs when the nervous system is stimulated by, for example, an injury, whereas neuropathic pain occurs when the nervous system itself is damaged.

Current treatments in neuropathic pain only provide meaningful relief for one in three patients, and all of the current market-leading drugs have serious side effects, as well as taking up to three weeks to begin to take effect.

Peptides (small proteins) from cone snail venom have attracted recent attention from scientists, as they can target receptors with a high degree of accuracy, thus eliminating severe side effects.

But peptides also degrade rapidly in the body. Professor Craik and Dr Clark have overcome this problem by engineering a circular peptide, using a circular protein backbone discovered by Professor Craik and found in plants such as violets.

The NHMRC Development grant will allow the researchers to further test their molecule to fully establish its therapeutic potential.

Successful outcomes from this project will provide additional confirmation of the suitability of our molecule as a treatment for neuropathic pain, Dr Clark said.

Armed with these data, we will be able to secure a commercial partner and develop this molecule into a tablet for sufferers of chronic p
'/>"/>

Contact: Bronwyn Adams
communications@uq.edu.au
61-733-462-134
Research Australia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Technology Promises Safer Organ Transplants and Soft Tissue Surgeries
2. Lung transplants in cystic fibrosis patients with life-threatening bacteria sparks debate at ISHLT
3. Parkinsons Disrupts Stem Cell Therapy Transplants
4. Lung transplants not dangerous for children with cystic fibrosis, after all
5. Study shows lifetime effects of pediatric liver transplants
6. ABC and NMDP Partner to Meet Growing Need for Stem Cell and Cord Blood Transplants, Assure Funding for Cord Blood Network, Encourage Minority Donor Recruitment
7. New technique improves outcome for living donor liver transplants
8. New Interventional Radiology Treatment Shows Hope for People With Complications from Bone Marrow, Stem Cell Transplants
9. NIH grant to Emory and pediatric partners aims to improve kidney transplants for children
10. Boston Scientific Announces First European Implants of New Devices to Treat Heart Failure and Sudden Cardiac Death
11. Small-Diameter Dental Implants Increasingly Popular In the US
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... , ... August 27, 2015 , ... Mesa Community ... than 2,100 applicants worldwide, selected based on academic rigor, leadership and engagement, to receive ... a baccalaureate degree. , Sypher will receive a medallion and a $7,500 scholarship to ...
(Date:8/27/2015)... Billings, Montana (PRWEB) , ... August 27, 2015 ... ... Disorders Association, the average annual cost to treat a patient with hemophilia is ... engaged in finding a cure and improving treatment. The RMHBDA exists to help ...
(Date:8/27/2015)... , ... August 27, 2015 , ... According to an ... Conference on Abdominal Wall Hernia Surgery involved many conversations between hernia experts surrounding the ... there, the article notes that many different experts have different ideas about which is ...
(Date:8/27/2015)... ... August 27, 2015 , ... In an article published July ... the city of New Orleans, highlighting a security firm that is tasked with providing ... tech oriented entrepreneur who worked with the city to provide private security when it ...
(Date:8/27/2015)... ... August 27, 2015 , ... Allegheny General Hospital (AGH), part ... medical centers in the United States to receive international recognition for an advanced, ... Extracorporeal Life Support Organization (ELSO) , an international consortium of healthcare institutions dedicated ...
Breaking Medicine News(10 mins):Health News:Mesa Community College Graduate Andrew Sypher Receives Hites Transfer Scholarship 2Health News:Mesa Community College Graduate Andrew Sypher Receives Hites Transfer Scholarship 3Health News:Avitus Group Encourages Business & Employee Community Involvement; Senior Level Staff Leads Way With Support of Rocky Mountain Hemophilia & Bleeding Disorders Association 2Health News:Avitus Group Encourages Business & Employee Community Involvement; Senior Level Staff Leads Way With Support of Rocky Mountain Hemophilia & Bleeding Disorders Association 3Health News:Avitus Group Encourages Business & Employee Community Involvement; Senior Level Staff Leads Way With Support of Rocky Mountain Hemophilia & Bleeding Disorders Association 4Health News:Recent Article on Hernia Mesh Developments Highlights Viable Options, But Shows a Need for Further Research, notes Dr. Shirin Towfigh 2Health News:Article on New Orleans Security Force Highlights the Abilities and Flexibility of Private Security, says Spear Security Inc. 2Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 2Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 3Health News:International Organization Honors Allegheny General Hospital's Advanced Lifesaving Program for Cardiac and Respiratory Failure 4
... Flomax Is Case Study of How Costly Drugs Drive Up ... According to a new report by Consumer Reports Best Buy ... widely advertised drug Flomax for treating the symptoms of enlarged prostate, and ... the 20 most commonly prescribed drugs in 2008. , ...
... 15 AMDL Inc. (NYSE ... China, announced today the second closing of a private placement offering ... The exclusive placement agent for the offering is Cantone Research ... 2009, AMDL sold $1,327,250 of 12% Series 2 convertible notes at ...
... gives a talk about his research, he begins with the ... supermodel died from severe sepsis in January after amputation of ... Martin, who is a fellow in allergy, pulmonary and ... Vanderbilt University that has come up with a high-tech approach ...
... yeast rice does well in small trial, but there are ... new study revives a running controversy about the purported cholesterol-lowering ... , Red yeast rice is produced when a yeast, ... used in Asian countries for more than a thousand years ...
... infections, heart problems, new advisory says , MONDAY, ... undergoing surgery are at greater risk of heart ... complications, according to a Scientific Advisory from the ... anesthesiologists and other health-care providers underestimate the seriousness ...
... This release is available in French . ... (BWF) has announced the recipients of the 2009 Investigators in ... Saleh was one of six recipients granted $500,000 over a ... of NLR-mediated innate immunity." "We are studying how the body ...
Cached Medicine News:Health News:Consumer Reports 'Best Buy Drug' for Enlarged Prostate Could Save Consumers Nearly $3,000 a Year 2Health News:Consumer Reports 'Best Buy Drug' for Enlarged Prostate Could Save Consumers Nearly $3,000 a Year 3Health News:Consumer Reports 'Best Buy Drug' for Enlarged Prostate Could Save Consumers Nearly $3,000 a Year 4Health News:AMDL Inc. Announces Second Closing of Private Placement of Series 2 Senior Notes 2Health News:AMDL Inc. Announces Second Closing of Private Placement of Series 2 Senior Notes 3Health News:Vanderbilt researchers pioneer an advanced sepsis detection and management system 2Health News:Vanderbilt researchers pioneer an advanced sepsis detection and management system 3Health News:Vanderbilt researchers pioneer an advanced sepsis detection and management system 4Health News:Vanderbilt researchers pioneer an advanced sepsis detection and management system 5Health News:A Substitute for Those Who Can't Take Statins? 2Health News:A Substitute for Those Who Can't Take Statins? 3Health News:Heart Association Warns of Surgery Risks in Obese 2Health News:MUHC researcher awarded $500,000 to study pathogenesis of infectious disease 2
(Date:8/27/2015)... Md. , Aug. 27, 2015  BioElectronics Corporation (OTC ... announced today that three abstracts featuring the use of ... at the 9 th Congress of the European ... 2-5 th September 2015. The Company will also ... Dr Gianluca Bagnato , department clinical and ...
(Date:8/27/2015)... 27, 2015  PinnacleHealth CardioVascular Institute enrolled the first patient ... the United States in a trial assessing ... for blockages in the main artery of the leg. The ... potentially less risk for stent fracture or re-narrowing after the ... multicenter clinical trial of the BioMimics 3D Stent System and ...
(Date:8/27/2015)... , Aug. 27, 2015   Americord Registry ... tissue , and placenta tissue banking company, ... blood banking e-commerce website. This new website makes the ... with an interactive shopping cart and checkout process. ... "Most cord blood banking websites make this service difficult ...
Breaking Medicine Technology:BioElectronics Selected to Present its Pain Research and Devices at the European Pain Federation Conference 2First Pennsylvania Patient Treated in Landmark Vascular Study 2Cord Blood Bank Revolutionizes Process of Online Cord Blood Banking 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: