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Computing the best high-resolution 3-D tissue images
Date:4/23/2012

combining their computational adaptive optics with graphics processors, looking forward to real-time in-vivo applications for surgery, minimally invasive biopsy and more.

For example, computational adaptive optics could be very useful for ophthalmologists. Boppart's group previously has developed various handheld optical tomography devices for imaging inside the eye, particularly retinal scanning. Aberrations are very common in the human eye, making it difficult to acquire clear images. But adaptive optics hardware is too expensive or too complicated for most practicing ophthalmologists. With a computational solution, many more ophthalmologists could more effectively examine and treat their patients.

"The effectiveness is striking," Boppart said. "Because of the aberrations of the human eye, when you look at the retina without adaptive optics you just see variations of light and dark areas that represent the rods and cones. But when you use adaptive optics, you see the rods and cones as distinct objects."

In addition, the ability to correct data post-acquisition allows the researchers to develop microscope systems that maximize light collection instead of worrying about minimizing aberrations. This could lead to better data for better image rendering.

"We are working to compute the best image possible," said Boppart, who also is affiliated with the Institute for Genomic Biology at the U. of I.


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Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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