Navigation Links
Computers make sense of experiments on human disease
Date:11/12/2008

useful analysis. This can be resolved by selecting a simpler model that corresponds only to the experimental data that actually exists. Delegates at the workshop heard how in the case of MS, selection of the model could be tuned to the data, to make best use of the actual experimental results obtained in a particular study, as explained by Jesper Tegner, another co-convenor of the ESF workshop, from the Atherosclerosis Research Unit at the Karolinska Institute Centre for Molecular Medicine (CMM) in Stockholm, Sweden.

"There was one exciting presentation on MS," said Tegner. "The immune system is clearly central for MS. However, the trick in the case of MS is to represent different aspects of the immune system according to the available data.The objective isn't to model the whole immune system. One interesting level of abstraction was the presentation of agent-based modelling of MS where individual cells operated as agents, thus omitting the intracellular machinery." In other words, the detailed interior workings of the cells could be ignored in this case because that would have made the model overcomplicated, with insufficient data at the different levels to produce any useful insights.

In other experiments, data about varying levels of gene expression was obtained, which required very different models with networks of graphs. These highlighted the patterns of gene expression associated with a particular disease, such as MS.

Yet another valuable application of computer-based mathematical disease models lies in studying the phenomenon of addiction to drugs such as nicotine and helping to reconcile conflicting theories, as Compte pointed out. "The neurobiology of nicotine addiction is a hotly debated field. In particular, there are two contending views on how neurons and their connections in subcortical nuclei are affected by nicotine. This computer model allows us to reconcile the apparently contradictory results obtained from in vitro
'/>"/>

Contact: Albert COMPTE
acompte@clinic.ub.es
34-932-275-400-4151
European Science Foundation
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Compromised US and Chinese Computers Launch Greatest Number of Cyber Attacks, According to SecureWorks Data
2. Heritage Victor Valley Medical Group to Donate Computers to Victorville Senior Citizen Club
3. Tongue Drive system lets persons with disabilities operate powered wheelchairs, computers
4. Idle computers offer hope to solve cancers mysteries through grid computing project
5. Computers as safe as medical experts in prescribing blood thinning drugs
6. General Dynamics Itronix Donates Computers to Humanitarian Expedition Fighting Malaria in Africa
7. Two Laptop Computers Missing From Lifebloods Main Office
8. Hand-held computers prod older adults to exercise more, Stanford study shows
9. U.S. Army Selects Cogon Systems to Develop Advanced Clinical Decision Support Tools for Hand Held Computers
10. Computers help chemists fight emerging infections
11. Renowned Kyudo (Zen archery) Master Kanjuro Shibata Sensei to Present in L.A.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... “Many people become overwhelmed by the ... issues and phone calls with insurance companies,” The Jones ... their free eBook on pedestrian and bicycle accidents ... and bicycle auto accident claims assures the injured individual ... professionally handling their case while they focus on recovering. ...
(Date:12/26/2014)... 26, 2014 Parker & Sons, ... best in heating, cooling and plumbing contractor services ... emergency services in 2014 with regard to air-conditioning ... Arizona is known for its incredibly hot summers. ... the intricacies and details of a wide variety ...
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) ... on the current treatment landscape, unmet needs, current ... market. Stivarga is a drug which is used ... Boehringer Ingelheim is developing nintedanib (BIBF-1120), an orally ... CRC in the US, Europe, and Japan. The ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of ... its new selection of black one-shoulder cocktail dresses . ... they are available at discounted prices, up to 70% off. ... last for three weeks only. You know, we have thousands ... interested in our new items can visit our website for ...
(Date:12/25/2014)... December 25, 2014 BambooFlooringChina.com sells many ... quality bamboo flooring. Today, the company announces big ... many styles and colors. , BambooFlooringChina.com is the world’s ... the promotion is valid until Jan. 20, 2015. , ... and woven with a natural thread. All the bamboo ...
Breaking Medicine News(10 mins):Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... ( Drosophila melanogaster ) males -- in which the activity ... -- show impairments in learning and memory as they age. ... deficits by treating the flies with drugs such as lithium, ... The research team -- Thomas A. Jongens, Ph.D., associate professor ...
... -- NewYork-Presbyterian Hospital, one of the country,s largest and most ... and #1 among ranked hospitals in the New York area, ... marks the 10th consecutive year that NewYork-Presbyterian has been listed ... Best Hospitals 2010-11 ranks 152 medical centers nationwide ...
... , THURSDAY, July 15 (HealthDay News) -- A study of ... than the recommended two hours of television a day. ... country," said study co-author Dr. John Oh, an epidemic intelligence ... and Prevention, working with Oregon Public Health. Experts have ...
... THURSDAY, July 15 (HealthDay News) -- For an hour after ... stroke increases, a small, preliminary study suggests. But even ... researchers noted that moderate drinking over the long-term might actually ... risk of ischemic stroke may be transiently elevated in the ...
... The Robert Wood Johnson Foundation, the nation,s largest philanthropy ... of all Americans, has chosen Dr. Paul Lipkin, Director ... for a highly coveted National Health Policy Fellowship. ... dramatic change, and the lives of millions are impacted ...
... of scientists, led by researchers at the University of California, ... responsible for a condition in which eye and brain development ... a potential remedy that would involve a simple, daily dietary ... disorders of glycosylation or CDG, a group of syndromes in ...
Cached Medicine News:Health News:Rescuing fruit flies from Alzheimer's disease 2Health News:Rescuing fruit flies from Alzheimer's disease 3Health News:Rescuing fruit flies from Alzheimer's disease 4Health News:NewYork-Presbyterian No. 6 hospital in nation, No. 1 in NY 2Health News:NewYork-Presbyterian No. 6 hospital in nation, No. 1 in NY 3Health News:Too Many Tots Watching Too Much TV: Study 2Health News:Too Many Tots Watching Too Much TV: Study 3Health News: Stroke Risk May Rise First Hour After Drinking 2Health News: Stroke Risk May Rise First Hour After Drinking 3Health News:Kennedy Krieger Institute's Dr. Paul Lipkin selected for national health policy fellowship 2Health News:UC San Diego researchers find cause of metabolic disease -- and possible cure 2Health News:UC San Diego researchers find cause of metabolic disease -- and possible cure 3
(Date:12/24/2014)... , Dec. 24, 2014  Conkwest, Inc., ... developing the proprietary Natural Killer (NK) cell-line platform, ... Dr. Patrick Soon-Shiong , NantWorks founder, physician ... definitive agreement to purchase approximately $48 million of ... with the investment, he will be named Co-Chairman ...
(Date:12/24/2014)... , Dec. 23, 2014 Echo Therapeutics, ... device company focused on skin permeation, continuous glucose ... Scott W. Hollander has been appointed Chief ... has more than 20 years of experience in ... and most recently served as Vice President, Business ...
(Date:12/24/2014)... Dec. 23, 2014   Assurex Health, a ... to healthcare providers for behavioral health and chronic ... $30 million in equity financing from new and ... , President and Chief Executive Officer. ... development of Assurex Health,s GeneSight ® ...
Breaking Medicine Technology:Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 2Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 3Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 4
... This programmable system automates the denaturation ... procedures, and provides walk-away convenience for ... cost unit accepts a wide range ... use, and reduces hands-on time by ...
... bucket rotor. ,The MicroPrep 2 is a ... bucket rotor and optional fixed angle rotor.,The ... of clinical, biomedical, industrial, and biotechnology applications. ... "swinging bucket centrifuge in a small, low ...
... StatSpin MP is a small, quiet, high-speed ... and suspension system which results in nearly ... rotors achieve both top speed and full ... easily be changed with a simple push-on/ ...
Used to provide drainage of urine from the bladder. All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open packages. Inte...
Medicine Products: