Navigation Links
Computers analyze environmental factors in diabetes
Date:5/20/2010

Like many complex diseases, diabetes results from the interplay of genetic and environmental factors. To examine genetic risk factors, scientists pore over the human genome sequence. Environmental factors have been trickier to pin down because there is no way to evaluate them comprehensively.

Now, researchers at Stanford University present what they call an environment-wide association study (EWAS) or to systematically examine the contributions of hundreds of factors in the development of Type 2 diabetes. This "enviromics" approach, which mirrors genome-wide association studies, harnesses high-speed computers and publicly accessible databases.

The first-of-its-kind study, which was funded by the National Institutes of Health (NIH), appears in the May 20, 2010, issue of PLoS One. The article is titled An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus.

The authors examined 226 separate environmental factors like nutrition and exposure to bacteria, viruses, allergens and toxins. They found that certain factors, notably a pesticide derivative and the environmental contaminant PCB, were strongly associated with the development of diabetes. Other factors, including the nutrient beta-carotene, served a protective role.

The scientists describe their work as a demonstration that computational approaches can reveal as much about environmental contributions to disease as about genetic factors. They posit that the technique could be applied to other complex diseases like obesity, hypertension and cardiovascular disorders.

The authors acknowledge that many challenges remain, including the fact that, unlike the genome, "the environment is boundless."


'/>"/>

Contact: Alisa Machalek
alisa.machalek@nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
Source:Eurekalert

Page: 1

Related medicine news :

1. Computers can effectively detect diabetes-related eye problems
2. Group Mobile adds Unitech Rugged Handheld Computers to its Product Offerings
3. Harnessing the Web and supercomputers to track pathogens as they evolve
4. Computers do better than humans at measuring some radiology images
5. ShowMyPC Provides First Online Service in the World to Access Personal Computers from Anywhere Using Microsoft Remote Desktop
6. MetaGeek Announces Chanalyzer Pro Spectrum Analysis Software for Wi- Spy, Adds Device Classification, Device Finder and Automated Reports
7. American Journal of Sports Medicine Study Analyzes Reliability of Pre-Season Concussion Testing
8. Heska Announces Installation of New Chemistry Analyzer
9. Rcadia COR Analyzer(R) System Demonstrates Potential in Emergency Department Triage of Chest Pain Patients at Low to Moderate Risk of Coronary Artery Disease
10. U.S. Must Do More to Cut Cases of Environmental Cancers
11. Twins Study Points to Environmental Cause for MS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... VA (PRWEB) , ... August 18, 2017 , ... More ... the Democratic Republic of Congo (DRC) thanks to an ambitious venture that conjoined the ... well as the generous support of the Liberty community. These shoes will save lives ...
(Date:8/18/2017)... (PRWEB) , ... August 18, ... ... d/b/a Quick International, LLC (“Quick”), a highly specialized asset-light logistics provider of ... entered into a definitive agreement to purchase Unitrans International Corporation, a division ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... of “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... , ... August 18, 2017 , ... ... handling handheld devices. Through an educational webinar, they will present the line of ... chance to learn how easy you can automate everyday pipetting tasks. , Ideal ...
(Date:8/18/2017)... ... August 18, 2017 , ... Hernandez ... consultations to communities throughout the greater DC region, is inaugurating a “New Leash ... rescuing local animals and training them to be companions for veterans in need. ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... 15, 2017  Axium Pharmaceuticals Inc., the creator of the drug ... the beginning stages of an IPO. The United ... the average cost of a prescription epilepsy drug being $450.00-$1200.00 for a ... AXIUM PHARMACEUTICALS, INC ... Another staggering figure is the fact that Americans spent $42 ...
(Date:8/15/2017)...  AOTI Inc. announced today that its fully owned ... a New York City Office in Yonkers, New York ... Wound Oxygen (TWO 2 ) homecare therapy. This new East Coast ... Care (ACHC) under the company,s DMEPOS accreditation for Home/Durable Medical Equipment ... Advanced Oxygen Therapy ...
(Date:8/11/2017)... Israel , Aug. 11, 2017 DarioHealth ... with mobile health and big data solutions, today announced ... on Monday, August 14 and host a conference call ... quarter 2017 operating and financial results and its strategy ... will be hosted by Erez Raphael , Chief ...
Breaking Medicine Technology: