Navigation Links
Computers analyze environmental factors in diabetes

Like many complex diseases, diabetes results from the interplay of genetic and environmental factors. To examine genetic risk factors, scientists pore over the human genome sequence. Environmental factors have been trickier to pin down because there is no way to evaluate them comprehensively.

Now, researchers at Stanford University present what they call an environment-wide association study (EWAS) or to systematically examine the contributions of hundreds of factors in the development of Type 2 diabetes. This "enviromics" approach, which mirrors genome-wide association studies, harnesses high-speed computers and publicly accessible databases.

The first-of-its-kind study, which was funded by the National Institutes of Health (NIH), appears in the May 20, 2010, issue of PLoS One. The article is titled An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus.

The authors examined 226 separate environmental factors like nutrition and exposure to bacteria, viruses, allergens and toxins. They found that certain factors, notably a pesticide derivative and the environmental contaminant PCB, were strongly associated with the development of diabetes. Other factors, including the nutrient beta-carotene, served a protective role.

The scientists describe their work as a demonstration that computational approaches can reveal as much about environmental contributions to disease as about genetic factors. They posit that the technique could be applied to other complex diseases like obesity, hypertension and cardiovascular disorders.

The authors acknowledge that many challenges remain, including the fact that, unlike the genome, "the environment is boundless."


Contact: Alisa Machalek
NIH/National Institute of General Medical Sciences

Page: 1

Related medicine news :

1. Computers can effectively detect diabetes-related eye problems
2. Group Mobile adds Unitech Rugged Handheld Computers to its Product Offerings
3. Harnessing the Web and supercomputers to track pathogens as they evolve
4. Computers do better than humans at measuring some radiology images
5. ShowMyPC Provides First Online Service in the World to Access Personal Computers from Anywhere Using Microsoft Remote Desktop
6. MetaGeek Announces Chanalyzer Pro Spectrum Analysis Software for Wi- Spy, Adds Device Classification, Device Finder and Automated Reports
7. American Journal of Sports Medicine Study Analyzes Reliability of Pre-Season Concussion Testing
8. Heska Announces Installation of New Chemistry Analyzer
9. Rcadia COR Analyzer(R) System Demonstrates Potential in Emergency Department Triage of Chest Pain Patients at Low to Moderate Risk of Coronary Artery Disease
10. U.S. Must Do More to Cut Cases of Environmental Cancers
11. Twins Study Points to Environmental Cause for MS
Post Your Comments:
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of the ... offering. The current unmet ... for MedImmune to enter. The US ageing population creates a ... considerable growth for effective anti-influenza medications. The introduction of a ... development is still in its infancy. Key ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Volumes: Global Analysis (United States, China, Japan, Brazil, United ... to their offering. ... healthcare business planners, provides surgical procedure volume data in ... with an in-depth analysis of growth drivers and inhibitors, ...
Breaking Medicine Technology: