Navigation Links
Computers analyze environmental factors in diabetes
Date:5/20/2010

Like many complex diseases, diabetes results from the interplay of genetic and environmental factors. To examine genetic risk factors, scientists pore over the human genome sequence. Environmental factors have been trickier to pin down because there is no way to evaluate them comprehensively.

Now, researchers at Stanford University present what they call an environment-wide association study (EWAS) or to systematically examine the contributions of hundreds of factors in the development of Type 2 diabetes. This "enviromics" approach, which mirrors genome-wide association studies, harnesses high-speed computers and publicly accessible databases.

The first-of-its-kind study, which was funded by the National Institutes of Health (NIH), appears in the May 20, 2010, issue of PLoS One. The article is titled An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus.

The authors examined 226 separate environmental factors like nutrition and exposure to bacteria, viruses, allergens and toxins. They found that certain factors, notably a pesticide derivative and the environmental contaminant PCB, were strongly associated with the development of diabetes. Other factors, including the nutrient beta-carotene, served a protective role.

The scientists describe their work as a demonstration that computational approaches can reveal as much about environmental contributions to disease as about genetic factors. They posit that the technique could be applied to other complex diseases like obesity, hypertension and cardiovascular disorders.

The authors acknowledge that many challenges remain, including the fact that, unlike the genome, "the environment is boundless."


'/>"/>

Contact: Alisa Machalek
alisa.machalek@nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
Source:Eurekalert

Page: 1

Related medicine news :

1. Computers can effectively detect diabetes-related eye problems
2. Group Mobile adds Unitech Rugged Handheld Computers to its Product Offerings
3. Harnessing the Web and supercomputers to track pathogens as they evolve
4. Computers do better than humans at measuring some radiology images
5. ShowMyPC Provides First Online Service in the World to Access Personal Computers from Anywhere Using Microsoft Remote Desktop
6. MetaGeek Announces Chanalyzer Pro Spectrum Analysis Software for Wi- Spy, Adds Device Classification, Device Finder and Automated Reports
7. American Journal of Sports Medicine Study Analyzes Reliability of Pre-Season Concussion Testing
8. Heska Announces Installation of New Chemistry Analyzer
9. Rcadia COR Analyzer(R) System Demonstrates Potential in Emergency Department Triage of Chest Pain Patients at Low to Moderate Risk of Coronary Artery Disease
10. U.S. Must Do More to Cut Cases of Environmental Cancers
11. Twins Study Points to Environmental Cause for MS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... Woodinville, WA (PRWEB) , ... May 05, 2016 ... ... better user experience, adapted to people’s every day living patterns, Amerec, a Seattle-based ... easy-to-use computer and smart phone app. , The user interface of the app, ...
(Date:5/5/2016)... ... May 05, 2016 , ... In honor of National Nurses Week ... all over the United States to thank a nurse who's made a difference in ... $5 to the American Red Cross of San Diego/Imperial Counties (up to $10,000) every ...
(Date:5/5/2016)... ... May 05, 2016 , ... When stiff and achy joints ... the pain that’s a common osteoarthritis (OA) symptom. Yet, numerous clinical studies point ... arthritis. , “Physical therapy exercises are commonly prescribed to individuals with osteoarthritis ...
(Date:5/5/2016)... ... May 05, 2016 , ... Chronic stress can have a silent, yet ... weaken the immune system and increase inflammation, both of which raise the risk of ... congenital heart disease program at Harvard-affiliated Massachusetts General Hospital. Chronic stress also can lead ...
(Date:5/5/2016)... ... May 05, 2016 , ... VisualDx announced today ... VisualDx is the first point of care diagnostic support system to be widely ... system speeds diagnosis, therapy decisions and patient education for emergency physicians, hospitalists and ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... , May 4, 2016 According ... Research entitled "Brain Computer Interface Market - Global Industry Analysis, ... global brain computer interface (BCI) market  is expected to ... market is estimated to expand at a CAGR of ... 2024. A BCI device provides collaboration between ...
(Date:5/4/2016)... Yissum Research Development Company ... that it had signed an exclusive world-wide licensing and ... novel protein degradation and immunomodulatory drugs for cancer and ... candidates representing first-in-class therapy for hematologic and solid malignancies. ... The novel technology was developed by Yinon ...
(Date:5/4/2016)... , May 4, 2016 ... addition of the  "Global Acute Ischemic Stroke ...  report to their offering.       ... Global Acute Ischemic Stroke Market and ... into Acute Ischemic Stroke pipeline products, Acute ...
Breaking Medicine Technology: