Navigation Links
Computer-aided design used for breast tissue reconstruction
Date:9/7/2011

A technology usually reserved for designing buildings, bridges and aircraft has now been used to aid breast tissue reconstruction in cancer patients.

In a study published today, Thursday 8 September, in IOP Publishing's journal Biofabrication, researchers used computer-aided design (CAD) to create an extremely accurate mould of a breast that was used as a visual aid to surgeons in tissue reconstruction operations.

Furthermore, CAD was used to design and produce patient-specific physical scaffolds that could potentially be used in conjunction with one of the most promising areas of medicine - tissue engineering.

In theory, patients' own cells could be harnessed and grown onto the highly specific scaffold and then transferred to the affected area, avoiding the need to transfer tissue from other parts of the body which can cause large scars, result in considerable blood loss and require five to ten hours of anaesthesia.

Study co-author, Professor Dietmar Hutmacher, said, "We would take a laser scan of the healthy breast and use the CAD modeling process to design a patient-specific scaffold in silico. We would then produce a scaffold of very high porosity and load it with the patient's own cells in combination with a hydrogel. The construct would then be implanted."

CAD the use of computer technology in the process of design holds several advantages over traditional pen and paper approaches including the ability to work to full scale, examine the design from all angles and maintain absolute accuracy.

After informed consent, 3D laser scanning was performed on three female patients who suffered from breast cancer. The images were then fed into a piece of CAD-software which produced a single image representing the patient's breast and surrounding thorax region.

This image was then "printed" to form a 3D mould which was used as an operative aid for surgeons who performed autologous tissue reconstructions the transferring of tissue from another part of the patient's body on each of the patients.

After each of the operations, the surgeons observed a more perfect shape with a higher degree of symmetry between the breasts whilst, more importantly, the patients reported a higher satisfaction of the surgery outcomes than the control group, again with respect to shape and symmetry of their breasts.

The long-term aim of the study, however, was on the development of a material that could be used in tissue engineering and it showed that CAD could be an effective way of achieving this.

A function was created using the CAD software that enabled the creation of a mould for any scanned tissue with the ability to independently tailor the porosity and pore size a property that is essential to the seeding and diffusing of cells throughout the structure and something that limits modern technologies.

Professor Hutmacher continued, "The development of a clinically translatable method of engineering adipose tissue for soft tissue reconstruction requires investigation of several components.

"There must be coordination between all key aspects of the tissue engineering process, including the selection of cell source, scaffold material, cellular environment, and means of device delivery in order for the engineering of any tissue to be successful."

An Institute of Physics spokesperson said, "This advance offers hope to women who have undergone mastectomies. It's enlightening to see how a technique, first designed for the construction of buildings, bridges and aircraft, is now being used in medicine."


'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Related medicine news :

1. Computer-aided detection does not improve mammogram accuracy
2. Computer-Aided Mammography Doesnt Improve Breast Cancer Detection: Study
3. Computer-Aided MRI Might Help Predict Alzheimers
4. Computer-aided detection is increasingly being used in screening and diagnostic mammography
5. Improved stepladder design may decrease injuries
6. TGen, Tecan and ASU Biodesign Institute develop sample preparation solution for proteomic research
7. NTU wins Platinum Award from BCA for sustainable design
8. Scientists design new anti-flu virus proteins using computational methods
9. Autism Speaks and Core77 Magazine name winners of Autism Connects design challenge
10. Experts Call for Twist on Football Helmet Design
11. Northwestern Medicine multiple sclerosis program earns national designation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... April 21, 2017 , ... Contrary to popular perception, ... is declining—and at noteworthy rates. Between 2002 and 2014, Salas-Wright and his colleagues ... violence in the United States. The study, Trends in Fighting and Violence ...
(Date:4/21/2017)... SALT LAKE CITY, Utah (PRWEB) , ... April ... ... leading provider of wilderness therapy treatment for adolescents and young adults, has kicked ... Thursday, April 20th-Sunday, April 23rd. This year’s theme is “Attachment Informed Therapy ...
(Date:4/21/2017)... ... 2017 , ... Young Asset Protection, an insurance provider and ... greater Pittsburgh metropolitan region, is joining forces with the local chapter of the ... , Variety the Children’s Charity is a national organization dedicated to empowering, enabling, ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... The adage ... Flex House, the next project in the company’s esteemed VISION House demonstration project series. ... use exactly the amount of resources they need to live affordably and abundantly without ...
(Date:4/21/2017)... ... April 21, 2017 , ... The ... of Record (AOR) for Theravent, Inc. , the makers of a revolutionary ... Foundation Consumer Healthcare, is now working to expand distribution in anticipation of a ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Eyevensys, a private biotechnology company developing its ... that enables the safe, local, sustained production of therapeutic ... of ophthalmic diseases, announces it has received approval from ... to advance its technology into clinical development. ... The EyeCET platform uses ...
(Date:4/19/2017)... The Mobile X-Ray product segment is the most ... the forecast period Mobile X-Ray segment is the ... X-Ray devices market, which is estimated to be valued at ... CAGR of 7% over the forecast period. Mobile X-Ray segment ... US$ 100 Mn in 2017 over 2016. The segment,s revenue ...
(Date:4/19/2017)... 19, 2017 The Global Effective Microorganisms ... 2022 report has covered and analysed the potential of Global ... market size, shares and growth factors. The report identifies and ... opportunities in the global market. ... Browse 152 Tables and Figures, 6 Major Company Profiles, ...
Breaking Medicine Technology: