Navigation Links
Compounds Identified That Might Treat Nerve Diseases
Date:1/19/2010

Researchers aim to 'chaperone' proteins involved in diseases like Parkinson's

TUESDAY, Jan. 19 (HealthDay News) -- Researchers report that they've developed a new way to find compounds that could become treatments for degenerative nerve disorders such as Alzheimer's, Huntington's and Parkinson's diseases.

The diseases cause proteins in nerve cells known as neurons to "misfold." In the new research, scientists say they've found molecules that play a role in the body's efforts to "chaperone" the molecules that fix the broken proteins.

The scientists studied one of the molecules and used rat neurons to show that it does indeed serve as a protective chaperone. Research in fruit flies showed the same thing.

Researchers say the study could lead to treatments that manipulate the chaperone molecules, leading to repair of the broken proteins.

"We found a creative way to identify new molecules that can activate the body's natural protein-folding machinery," senior author Dennis J. Thiele, professor of pharmacology and cancer biology at Duke University Medical Center in Durham, N.C., said in a news release.

The research appeared in the Jan. 19 online issue of PLoS Biology.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more on Parkinson's disease.



-- Randy Dotinga



SOURCE: Duke University, news release, Jan. 19, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Prenatal exposure to flame-retardant compounds affects neurodevelopment of young children
2. Marijuana Compounds Could Beat Back Brain Cancer
3. Spice Compounds May Stem Tumor Growth
4. Amylin Pharmaceuticals and Takeda Enter into Worldwide Agreement to Co-Develop and Commercialize Compounds for Obesity
5. Study shows how to boost value of Alzheimers-fighting compounds
6. New class of compounds discovered for potential Alzheimers disease drug
7. Novel light-sensitive compounds show promise for cancer therapy
8. Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels
9. Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009
10. Newly Identified Compounds May Inhibit Strep Infection
11. PRA SPEAKING EVENT: Phase I Studies with Hepatitis C Compounds in Healthy Volunteers and Patients: Views from Inside
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... February 05, 2016 , ... Francisco Canales, MD and Heather ... Napa Valley office. The technique utilizes the body’s own healing abilities to quickly ... Furnas, are part of only a select few cosmetic surgeons bringing this procedure ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... devoted exclusively to funding innovative lymphoma research and serving the lymphoma community through ... poised to once again host, Swirl, A Wine Tasting Event at the La ...
(Date:2/5/2016)... York (PRWEB) , ... February 05, 2016 , ... Regular ... and find themselves having to wait longer to access the treadmills. It’s a predictable ... Year’s resolutions to lose weight and get in shape by joining gyms, starting new ...
(Date:2/5/2016)... New York, New York (PRWEB) , ... February 05, 2016 , ... ... (APDA) announced the election of Patrick McDermott as Chairman of the National Board of ... welcome Pat as Chairman of the Board,” stated Leslie A. Chambers , APDA ...
(Date:2/5/2016)... ... ... Colorize is a web theme package created exclusively for Final ... dynamic moving camera. Colorize is perfect for personal and web related videos and its ... to 5 focus points per scene, stage floor scene presets that are great for ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 France , Germany ... UK, and Israel ). It includes a 10-year epidemiology ... GD, segmented by age and sex in these markets. GD epidemiology report ... is in-depth, high quality, transparent and market-driven, providing expert analysis of disease ... Germany , Italy , Spain ...
(Date:2/4/2016)... LONDON , Feb. 4, 2016 ... to achieve significant growth as next generation systems ... and use radiology for cancer surgery. New systems ... radiological overdosing that has been such a problem ... be delivered. Radiosurgery robots take cancer surgery far ...
(Date:2/4/2016)... , Feb. 4, 2016 Summary ... common cancer and the most common cancer in women ... the disease exceedingly prevalent. The number of women diagnosed ... decades, but the number of deaths has declined due ... cancer treatment has been revolutionized in the past four ...
Breaking Medicine Technology: