Navigation Links
Compound found in common wart treatment shows promise as leukemia therapy
Date:10/26/2011

Arlington, Va. -- A new potential leukemia therapy targets only cancer cells, while leaving healthy cells alone. Many current chemotherapy treatments affect cancer cells and healthy cells, causing significant side effects, such as fatigue, hair loss, nausea, anxiety and depression. This research is being presented at the 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Washington, D.C., Oct. 23 27.

Leukemia is a cancer of the blood and bone marrow, the spongy center of bones where blood cells are formed. According to the Leukemia and Lymphoma Society, an estimated 43,050 people were diagnosed with leukemia in the U.S. in 2010.

Lead researcher and AAPS fellow, Peter A. Crooks, Ph.D., and his colleagues from the University of Arkansas for Medical Sciences have developed a potent compound that only impacts cancer cells, and starts killing them as early as four hours after treatment begins.

"This is one of the most potent and selective compounds I have ever seen during my more than 30-year career," said Crooks.

The molecules used to create this anti-leukemic agent are structurally similar to the compound found in many gout treatments and over-the-counter products used to treat warts, which also prevent cell growth. This agent is able to reach cancer cells before they mature, so catching the disease in its early stages will eradicate it quickly. This is especially vital for treating acute myeloid leukemia, which progresses rapidly without treatment.

"It's good to get excited in the early stages of research when you discover a treatment that could potentially be as outstanding as this," said Crooks. "However, the next phase is to test the treatment in animal models and pinpoint the most effective delivery method."


'/>"/>
Contact: Stacey May
MayS@aaps.org
703-459-7677
American Association of Pharmaceutical Scientists
Source:Eurekalert

Page: 1

Related medicine news :

1. Compound shows promise against intractable heart failure
2. Sigma-Aldrich Reaches Agreement to Sell Pfizers Bioactive Small Molecule Compounds
3. Chemotherapy plus synthetic compound provides potent anti-tumor effect in pancreatic cancers
4. New pyrimidine compounds may lead to improved treatments for childhood brain cancer
5. Researchers find compound effective in destroying antibiotic-resistant biofilms
6. Compound enhances cancer-killing properties of agent in trials
7. Concentration, timing and interactions are key when it comes to dietary compounds
8. Breast cancer cells regulate multiple genes in response to estrogen-like compounds
9. Plant compound resveratrol shown to suppresses inflammation, free radicals in humans
10. Compounds in non-stick cookware may be associated with elevated cholesterol in children and teens
11. New investigational compound targets pancreatic cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... 2014 (HealthDay News) -- Regularly checking the pulse of ... report. "Screening pulse is the method of choice ... 65 who have never had a stroke. Our study ... easy way to identify people who might need more ... author Dr. Bernd Kallmunzer, of Erlangen University in Germany. ...
(Date:7/23/2014)... Rich Dad® Education, a leader in financial ... yard sale to support Habit for Humanity of Lee and ... proceeds will be donated to Habitat for Humanity. Additionally, all ... to the Habitat for Humanity ReStore thrift store located at ... One of the highlights of the yard sale was a ...
(Date:7/23/2014)... 23, 2014 Bodybuilding.com, the Internet’s most-visited ... of nutritional supplements, has officially opened the polls for ... , the fastest growing sports nutrition company, is up ... of the Year, Best Tasting Protein of the Year- ... of the year - Whey-HD™, Pre-workout Supplement of the ...
(Date:7/23/2014)... PA (PRWEB) July 23, 2014 Four ... have been lauded in the latest ranking of the ... Report . Released online today and slated for ... Guide recognizes Allegheny General Hospital (AGH), Forbes Hospital, Saint ... medical centers across multiple clinical specialties. , ...
(Date:7/23/2014)... July 23, 2014 (HealthDay News) -- For patients infected ... therapy may help control both viruses, a small study ... to improve treatment strategies for people with the two ... with antiretroviral medications plays an important role in the ... said study leader Dr. Kenneth Sherman, a professor of ...
Breaking Medicine News(10 mins):Health News:Routine Pulse Check May Prevent Second Stroke, Study Says 2Health News:Rich Dad Education Charity Yard Sale Raises Over $650 for Habitat for Humanity of Lee and Hendry Counties 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 3Health News:Four Allegheny Health Network Hospitals Named High Performers by U.S. News 2Health News:Four Allegheny Health Network Hospitals Named High Performers by U.S. News 3Health News:HIV Meds May Also Help Control Hepatitis C, Study Finds 2
... cancer tumours change their hormonal status throughout the course ... treatment for the patient is usually only based on ... biopsy verifications of any relapse will be very important ... Swedish researcher will tell the 2011 European Multidisciplinary Cancer ...
... develop bone metastases, and controlling the pain these cause ... III trial of a bisphosphonate drug in these patients ... is as good for pain relief as single dose ... the trial were presented today (Sunday) at the 2011 ...
... firm evidence that giving radiotherapy between or during chemotherapy ... the risk of the cancer recurring in the breast ... has minimal adverse side-effects and no detrimental effect on ... the SEquencing of Chemotherapy and Radiotherapy in Adjuvant Breast ...
... Melanoma of the eye (ocular or uveal melanoma) frequently spreads ... no effective treatment and patients die within an average of ... live for a year. Now, final results from a phase ... the time patients can live without the disease progressing. ...
... FRIDAY, Sept. 23 (HealthDay News) -- Primary care and ... a patient to another doctor, a new study finds. ... after clinical expertise, primary care doctors consider issues such ... to base their decisions on their other patients, experiences ...
... Researchers have identified five new genes that play a role ... -- the most common cause of premature death and disability ... The international consortium said their discovery could help scientists predict ... condition. In conducting the study, published online Sept. 22 ...
Cached Medicine News:Health News:Breast cancer tumor make-up changes through the course of disease 2Health News:Breast cancer tumor make-up changes through the course of disease 3Health News:Bone-strengthening drug gives pain relief in prostate cancer bone metastases 2Health News:Bone-strengthening drug gives pain relief in prostate cancer bone metastases 3Health News:Radiotherapy between or during chemotherapy cycles reduces risk of breast cancer recurrence 2Health News:Radiotherapy between or during chemotherapy cycles reduces risk of breast cancer recurrence 3Health News:Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients 2Health News:Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients 3Health News:Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients 4Health News:Scientists ID More Genes Linked to Heart Disease 2
(Date:7/23/2014)... MINNEAPOLIS , July 23, 2014 ... they have added 14 new vendors so far ... Creekridge,s newest vendors are from both ... mid-size domestic organizations to large, well-known multi-national companies. ... Creekridge,s diversified suite of financing products including: standard ...
(Date:7/23/2014)... , July 23, 2014  Mezzion Pharma Co. ... to evaluate the use of udenafil to treat adolescents ... ventricle heart defects. The clinical program will follow protocols ... the Pediatric Heart Network (PHN), a multi-center clinical research ... Institute (NHLBI) of the National Institutes of Health (NIH). ...
(Date:7/23/2014)... , July 23, 2014  Lightlake Therapeutics ... addiction treatments based on its expertise in opioid ... investigational new drug application ("IND") with respect to ... also announced today that it has received an ... Abuse ("NIDA"), part of the National Institutes of ...
Breaking Medicine Technology:Creekridge Capital Signs Several New Vendor Partners 2Mezzion Pharma Initiates Clinical Development Program To Evaluate Udenafil In Adolescents With Single Ventricle Heart Defects 2Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 2Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 3
... Orthopedic Group, Inc. (NYSE: HGR ) announced that it continues ... Prosthetics of Texas , Nebraska Orthotic and Prosthetic Services, and Spectrum ... with annual revenues of $14.0 million . , ... "These companies are leaders in their communities ...
... June 22 Draeger Medical Canada, Inc. today announced ... System (AIMS) for the Capital District Health Authority and IWK Health Centre ... , , ... of the most comprehensive information technology solution for the safe delivery and ...
Cached Medicine Technology:Hanger Orthopedic Group, Inc. Announces Three Acquisitions With Annual Revenues of $14.0 Million 2Capital District Health Authority and IWK Health Centre to Implement Anesthesia Information Management System 2Capital District Health Authority and IWK Health Centre to Implement Anesthesia Information Management System 3
... achieves a secure clot, targeted to the ... hemostasis is needed, when control of bleeding ... and cautery, is ineffective or impractical., CROSSEAL* ... of human Biologically Active Component (BAC) and ...
Mastisol Liquid Adhesive is a clear, non-irritating, and non-water-soluble liquid adhesive that secures the most difficult dressings for an extended period of time. Mastisol is 7 to 10 times stickier...
... Indermil® tissue adhesive is indicated for ... laparoscopic incisions, and trauma-induced lacerations in areas ... thoroughly-cleansed, and have easily approximated skin edges. ... tissue adhesive may act as a barrier ...
The first Ethyl-2-Cyanoacrylate tissue adhesive in a tube that is more economical than sutures!...
Medicine Products: