Navigation Links
Compound found in common wart treatment shows promise as leukemia therapy
Date:10/26/2011

Arlington, Va. -- A new potential leukemia therapy targets only cancer cells, while leaving healthy cells alone. Many current chemotherapy treatments affect cancer cells and healthy cells, causing significant side effects, such as fatigue, hair loss, nausea, anxiety and depression. This research is being presented at the 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Washington, D.C., Oct. 23 27.

Leukemia is a cancer of the blood and bone marrow, the spongy center of bones where blood cells are formed. According to the Leukemia and Lymphoma Society, an estimated 43,050 people were diagnosed with leukemia in the U.S. in 2010.

Lead researcher and AAPS fellow, Peter A. Crooks, Ph.D., and his colleagues from the University of Arkansas for Medical Sciences have developed a potent compound that only impacts cancer cells, and starts killing them as early as four hours after treatment begins.

"This is one of the most potent and selective compounds I have ever seen during my more than 30-year career," said Crooks.

The molecules used to create this anti-leukemic agent are structurally similar to the compound found in many gout treatments and over-the-counter products used to treat warts, which also prevent cell growth. This agent is able to reach cancer cells before they mature, so catching the disease in its early stages will eradicate it quickly. This is especially vital for treating acute myeloid leukemia, which progresses rapidly without treatment.

"It's good to get excited in the early stages of research when you discover a treatment that could potentially be as outstanding as this," said Crooks. "However, the next phase is to test the treatment in animal models and pinpoint the most effective delivery method."


'/>"/>
Contact: Stacey May
MayS@aaps.org
703-459-7677
American Association of Pharmaceutical Scientists
Source:Eurekalert

Page: 1

Related medicine news :

1. Compound shows promise against intractable heart failure
2. Sigma-Aldrich Reaches Agreement to Sell Pfizers Bioactive Small Molecule Compounds
3. Chemotherapy plus synthetic compound provides potent anti-tumor effect in pancreatic cancers
4. New pyrimidine compounds may lead to improved treatments for childhood brain cancer
5. Researchers find compound effective in destroying antibiotic-resistant biofilms
6. Compound enhances cancer-killing properties of agent in trials
7. Concentration, timing and interactions are key when it comes to dietary compounds
8. Breast cancer cells regulate multiple genes in response to estrogen-like compounds
9. Plant compound resveratrol shown to suppresses inflammation, free radicals in humans
10. Compounds in non-stick cookware may be associated with elevated cholesterol in children and teens
11. New investigational compound targets pancreatic cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... 2014 Ale Gicqueau, President and Chairman ... Data Visualization for Clinical Trials at the upcoming ... Francisco on Friday, September 26, 2014. , PhUSE ... its inception, PhUSE has expanded from its roots as ... platform for the discussion of topics encompassing the work ...
(Date:9/23/2014)... 23, 2014 With the emergence of ... of all tobacco products, retail chains are transforming the ... to patients, customers, and shoppers. In this capacity, Inside ... retail pharmacy healthcare to share their knowledge on patient ... know to coordinate care with other colleagues inside the ...
(Date:9/23/2014)... Published by Nationwide Lifts, the book is designed to inspire ... mobility in a new way, using equipment that is affordable, ... that equipment and can bring mobility and freedom back ... business, I’ve seen so many people struggle with what to ... mobility issues,” said Andy Darnley, co-founder and president of Nationwide ...
(Date:9/23/2014)... Dallas-based luxury linen purveyor Peacock Alley ... as vice president of product development. Eades will be responsible ... primary lead on global sourcing for the company. In her ... product development group and sourcing group and will be the ... notes, "Peacock Alley is a brand I have admired for ...
(Date:9/23/2014)... Positioning themselves as the leading provider ... Tactical products to their basket which customers can ... good name in the market and customers believe in ... products and now customers will get a myriad of ... MilSpec Tactical Safe which uses an authentic military specification ...
Breaking Medicine News(10 mins):Health News:Clinovo Sponsors and Presents at Pharmaceutical Users Software Exchange (PhUSE) SDE in San Francisco 2Health News:Retail Pharmacies at the Forefront of Primary Care Innovation 2Health News:Nationwide Lifts, America’s Leader in Home Elevators, Is Proud to Announce the Release of Its First Book, “Stair Lifts: Move Up, Not Out!” 2Health News:Luxury Linen Purveyor Peacock Alley Announces New Vice President of Product Development 2Health News:GunSafes.com Now Offers Secure Tactical Range of Gun Safes 2
... of pesto sold in Ontario and Quebec following the warning ... not to eat two kinds of pesto – not to ... Sundried Tomatoes pesto - sold in Ontario and Quebec. ... affected products were sold in 200 ml glass jars in ...
... According to New York health officials, condoms would have more ... process of considering various options of casing the condoms. ... colourful subway theme. A novel way of wrapping the condom ... the same by the people. , ,On an ...
... created the world's first canine clone, have cloned another breed ... the water and bird hunting// skills. ,A ... College of Veterinary Medicine of Seoul National University (SNU) cloned ... team, formerly led by the nation's disgraced stem cell scientist ...
... an intranasal influenza vaccine using a novel adjuvant ... the first tablet// flu vaccine formulation. ... recently completed a preclinical study on intranasal formulation, ... start this autumn, and the vaccine will follow ...
... hope for treating those with nicotine addiction, scientists have come out ... brain called the insula can result in a person not wanting ... of the brain and is thought to translate information from other ... cravings for a drug. , The study published in ...
... points to folic acid being able to prevent facial clefts; ... British study//. , Pregnant women have been prescribed folic ... been understood to reduce the risk of babies being born ... a study conducted by Allen Wilcox of the National Institute ...
Cached Medicine News:Health News:Seoul Lab Clones Poodle 2Health News:Oral Flu Vaccine On The Horizon In Russia 2Health News:Chain-Smokers can Kick the Habit –A ‘brainy’ I 2
(Date:9/22/2014)... Sept. 22, 2014 Children,s National Health ... Sept. 29 at 5 p.m. EDT for its ... in response to continued strong interest from inventors.  ... will be awarded to the winning presentations at ... Symposium hosted by Children,s National in October. For ...
(Date:9/22/2014)... and SHANGHAI , Sept. ... (BHG), a global knowledge leader in healthcare technology, ... to support healthcare innovation in China ... connected health technologies. Continua and BHG announced this ... being held this week in Washington, ...
(Date:9/22/2014)... , Sept. 22, 2014 ... of the "Global Ablation Technologies (Radiofrequency, Ultrasound, ... 2019" report to their offering. ... the global ablation technologies market has been divided ... ultrasound, microwave, cryotherapy, hydrothermal, and hydromechanical ablation technologies. ...
Breaking Medicine Technology:Calling all medical innovators: Submit your pediatric medical device pitch for Children's National competition by Sept. 29 2Calling all medical innovators: Submit your pediatric medical device pitch for Children's National competition by Sept. 29 3Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 2Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 3Continua and Borderless Healthcare Group Form Strategic Partnership, Launch the Healthcare Technology Innovation Center in Shanghai 4Global Ablation Technologies (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave) Market - Forecasts to 2019 2Global Ablation Technologies (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave) Market - Forecasts to 2019 3
... ventricular drainage set (EVD set) ... for external ventricular drainage. It ... with a ventricular catheter or ... probe from the Aesculap Spiegelberg ...
... The Trippi-Wells and Universal tongs were ... are needed than can be safely provided ... ring. Titanium construction. Kit complete with four ... or four pin application. Skull pins at ...
... neuro and skull base surgery. Complete ... surgery, pediatric neurosurgery, bony defects of ... base regions, neuro trauma. Dedicated neuro/skull ... in one compact kit. MRI and ...
Hand Drill, with two-position Handle, with Jacob three-jaw chuck, wrench-locked for changing twist drills up to 6 mm...
Medicine Products: