Navigation Links
Compound found in common wart treatment shows promise as leukemia therapy
Date:10/26/2011

Arlington, Va. -- A new potential leukemia therapy targets only cancer cells, while leaving healthy cells alone. Many current chemotherapy treatments affect cancer cells and healthy cells, causing significant side effects, such as fatigue, hair loss, nausea, anxiety and depression. This research is being presented at the 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Washington, D.C., Oct. 23 27.

Leukemia is a cancer of the blood and bone marrow, the spongy center of bones where blood cells are formed. According to the Leukemia and Lymphoma Society, an estimated 43,050 people were diagnosed with leukemia in the U.S. in 2010.

Lead researcher and AAPS fellow, Peter A. Crooks, Ph.D., and his colleagues from the University of Arkansas for Medical Sciences have developed a potent compound that only impacts cancer cells, and starts killing them as early as four hours after treatment begins.

"This is one of the most potent and selective compounds I have ever seen during my more than 30-year career," said Crooks.

The molecules used to create this anti-leukemic agent are structurally similar to the compound found in many gout treatments and over-the-counter products used to treat warts, which also prevent cell growth. This agent is able to reach cancer cells before they mature, so catching the disease in its early stages will eradicate it quickly. This is especially vital for treating acute myeloid leukemia, which progresses rapidly without treatment.

"It's good to get excited in the early stages of research when you discover a treatment that could potentially be as outstanding as this," said Crooks. "However, the next phase is to test the treatment in animal models and pinpoint the most effective delivery method."


'/>"/>
Contact: Stacey May
MayS@aaps.org
703-459-7677
American Association of Pharmaceutical Scientists
Source:Eurekalert

Page: 1

Related medicine news :

1. Compound shows promise against intractable heart failure
2. Sigma-Aldrich Reaches Agreement to Sell Pfizers Bioactive Small Molecule Compounds
3. Chemotherapy plus synthetic compound provides potent anti-tumor effect in pancreatic cancers
4. New pyrimidine compounds may lead to improved treatments for childhood brain cancer
5. Researchers find compound effective in destroying antibiotic-resistant biofilms
6. Compound enhances cancer-killing properties of agent in trials
7. Concentration, timing and interactions are key when it comes to dietary compounds
8. Breast cancer cells regulate multiple genes in response to estrogen-like compounds
9. Plant compound resveratrol shown to suppresses inflammation, free radicals in humans
10. Compounds in non-stick cookware may be associated with elevated cholesterol in children and teens
11. New investigational compound targets pancreatic cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... , ... July 28, 2015 , ... Women fear developing ... reason is that cancer, heart attack, and stroke are treatable, but there is little ... can do is to take part in a clinical trial, reports the July 2015 ...
(Date:7/28/2015)... CA (PRWEB) , ... July 28, 2015 , ... ... of Acute Coronary Syndromes (ACS-Heart Attack, Sudden Death, or Angina), many of whom ... cardiology is the identification of individuals with active yet undetected sub-clinical disease, who ...
(Date:7/28/2015)... ... July 28, 2015 , ... ... for identifying Top Doctors, has based its selection process on the foundation of ... in their medical specialties, in any area of medicine and in any part ...
(Date:7/28/2015)... ... 2015 , ... One of the most common running related ... plantar fasciitis . Zensah, the Miami-based compression brand, offers a product that can ... the Zensah Ankle Support’s primary benefits include helping support the ankle, reduce swelling, ...
(Date:7/28/2015)... ... July 28, 2015 , ... Nurses across all settings ... up to 57 million Americans may need mental health services (SAMHSA, 2013) and the ... Psychiatric-mental health RNs are one of the largest workforces who provide care to ...
Breaking Medicine News(10 mins):Health News:Fight Alzheimer's By Taking Part in a Clinical Trial, From the July 2015 Harvard Women's Health Watch 2Health News:Fight Alzheimer's By Taking Part in a Clinical Trial, From the July 2015 Harvard Women's Health Watch 3Health News:Utility of a novel coronary artery disease biomarker algorithm in modifying physician adherence to guideline therapy presented at 20th World Congress on Heart Disease 2Health News:Fort Myers Plastic Surgeon Recognized as One of the America’s “Top Doctors®” by Prestigious Castle Connolly Medical Ltd. for 5 Years in a Row 2Health News:Fort Myers Plastic Surgeon Recognized as One of the America’s “Top Doctors®” by Prestigious Castle Connolly Medical Ltd. for 5 Years in a Row 3Health News:Zensah Releases Compression Sleeve To Relieve Ankle Pain and Plantar Fasciitis 2Health News:American Psychiatric Nurses Association Transitions in Practice Certificate Program to Improve Mental Health Care Through Continuing Nursing Education 2Health News:American Psychiatric Nurses Association Transitions in Practice Certificate Program to Improve Mental Health Care Through Continuing Nursing Education 3Health News:American Psychiatric Nurses Association Transitions in Practice Certificate Program to Improve Mental Health Care Through Continuing Nursing Education 4
... A novel gene called rumi regulates Notch signaling by ... Notch protein that extends outside a cell, said researchers ... Brook University in New York in a report that ... governed by the Notch protein determines cell fate determination ...
... works for allergic asthma, rhinitis, conjunctivitis or insect ... If you have allergic asthma, rhinitis, conjunctivitis or ... candidate for allergy shots, also known as immunotherapy. ... of Allergy, Asthma & Immunology. , "Immunotherapy is ...
... MYL ),today announced that it intends to appeal ... for the District of Columbia against Mylan and its ... of the,pending Lorazepam and Clorazepate antitrust cases. The first ... disclosed, in June 2005, a jury in the district ...
... Society of Plastic Surgeons (ASPS) today addressed concerns,regarding ... events following,a recent petition from a consumer group., ... U.S. Food and Drug,Administration (FDA) implement labeling changes ... one million people have been treated with BOTOX ...
... Unland, President of the,Chicago-based Health Capital Group, urged hospitals, ... their existing debt instruments, their,obligations and their capital and ... Problems with some major banks and bond insurers have ... do so for some time to come,resulting in both ...
... no medical benefit; heart expert calls it ,second-line, ... The controversy surrounding the highly promoted cholesterol-lowering drug ... they would review the medication,s effectiveness, but only ... debate began earlier this month when preliminary results ...
Cached Medicine News:Health News:Notch-ing glucose into place 2Health News:Allergy Shots Are Effective Treatment for Symptoms 2Health News:Mylan Provides Update Relating to Ongoing Lorazepam and Clorazepate Litigation 2Health News:ASPS Addresses Concerns Regarding BOTOX Treatments 2Health News:Health Capital Group Warns of Fallout to Hospitals From the Subprime Mortgage Crisis and Urges Hospitals to Immediately Reassess Existing Debt Structures and Capital Financing Plans 2Health News:FDA Will Wait for Trial Results on Vytorin 2Health News:FDA Will Wait for Trial Results on Vytorin 3
(Date:7/28/2015)... Ill. , July 28, 2015 Today,s ... on par with their levels of clinical excellence. Today ... Annual Meeting & Clinical Lab Expo, Sysmex is announcing ... a comprehensive and intuitive ecosystem that will help laboratories ... key areas, Sysmex aims to add even more value ...
(Date:7/28/2015)... 2015 Research and Markets ... "Global Post-traumatic Stress Disorder Therapeutics Market 2015-2019" ... therapeutics market to grow at a CAGR of 1.09% ... the present scenario and the growth prospects of the ... calculate the market size, the report considers revenue generated ...
(Date:7/28/2015)... , July 28, 2015   DigiPath Labs ... DIGP), is combining efforts with True North Laboratory of ... Romer Labs , a leading global supplier of diagnostic ... utilizing Romer Labs, rapid diagnostic test kits ... in cannabis. "This joint effort is expected ...
Breaking Medicine Technology:Sysmex Moves Beyond a Better Box 2Sysmex Moves Beyond a Better Box 3Sysmex Moves Beyond a Better Box 4Global Post-traumatic Stress Disorder Therapeutics Market 2015-2019 - Growing Number of Accidents and Violence Worldwide Drives the Market 2DigiPath Labs Partners with Romer Labs to Validate Food-Borne Pathogen and Mycotoxin Testing Solutions for Cannabis 2DigiPath Labs Partners with Romer Labs to Validate Food-Borne Pathogen and Mycotoxin Testing Solutions for Cannabis 3
... Get content from Novo Nordisk A/S at: ... Novo Nordisk announced on March 15 that the ... approved Victoza® for the treatment of type 2 ... the first once-daily human Glucagon-Like Peptide-1 (GLP-1) analogue ...
... patients in China will gain access to Varian,s state-of-the-art ... center is acquiring a GammaMed® brachytherapy afterloader from Varian ... high dose rate afterloader supplied to Chinese hospitals by ... Jilin University No. 1 Hospital in Jilin will ...
Cached Medicine Technology:Video from Novo Nordisk A/S available on thenewsmarket.com: Novo Nordisk Receives Approval for Victoza in China 2First Varian High Dose Rate Brachytherapy Afterloader Supplied to Leading China Cancer Hospital 2
... advanced 16 to 64 channel sleep diagnostic ... 16 to 64 channel sleep diagnostic collection ... sleep event recording or post recording. The ... recorded during sleep events including current number ...
Aurora is a powerful Windows-based digital PSG instrument providing complete data acquisition, recording and review capabilities in one flexible package. The Aurora offers the most feature-packed PSG...
... gold-ball electrodes in a double-horn assembly ... electrode is in a ball and ... Supporting bone clamp design simplifies three ... braided, Teflon-coated wires terminate in a ...
... Medelec Synergy N-EP provides total testing ... smaller instrument is driven by space ... testing equipment on the move ... 2, 5, or 10-channel Medelec Synergy ...
Medicine Products: