Navigation Links
Compound Targets, Destroys Cancer Stem Cells in Mice
Date:8/13/2009

Therapeutic possibilities are uncertain, researchers say

THURSDAY, Aug. 13 (HealthDay News) -- Researchers have identified a chemical able to seek out and destroy the stem cells that scientists believe give rise to cancer recurrence after treatment.

A growing body of research is showing that cancer stem cells play a role in cancer metastasis and in causing cancer to reappear even after treatment seems to have eradicated the initial tumor.

"Evidence is accumulating rapidly that cancer stem cells are responsible for the aggressive powers of many tumors," including breast, prostate, lung and others, said study author Robert Weinberg, a member of the Whitehead Institute for Biomedical Research at Massachusetts Institute of Technology.

Yet studying cancer stem cells in the lab has proven problematic. The cells, already fewer in number than other types of tumor cells, tend to lose their stem cell-like properties when grown outside the body.

In the study, which appears in the Aug. 13 online issue of Cell, researchers were able to generate large numbers of cancer cells with stem cell-like qualities through a technique called "epithelial-to-mesenchymal transition," which causes the cells to take on characteristics similar to stem cells.

"A critical aspect of our work was to generate relatively homogenous and stable populations of cancer stem-like cells that could then be used for screening," said co-lead study author Tamer Onder, a former graduate student at the Whitehead Institute for Biomedical Research and now postdoctoral research fellow at Children's Hospital in Boston. "We were able to achieve this by inducing the cancer cells into an epithelial-to-mesenchymal transition using novel reagents that we had developed in the lab."

Researchers then analyzed thousands of chemical compounds to determine which ones were effective in killing breast cancer stem cells.

They found tha
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. First compound that specifically kills cancer stem cells found
2. New class of compounds discovered for potential Alzheimers disease drug
3. DSM Announces SafeBridge(R) Potent Compound Safety Certification
4. New Compounding Pharmacy Videos Provide Product Information, Teach Safety
5. Novel light-sensitive compounds show promise for cancer therapy
6. Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels
7. New antibiotics could come from a DNA binding compound that kills bacteria in 2 minutes
8. Natura Therapeutics and USF receive NIH grant to study green tea compound for Alzheimers
9. Bayer to Present Data on Development Compound BAY 73-4506 at 45th Annual Meeting of the American Society of Clinical Oncology
10. Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009
11. GADA Points to Safety of FDA Approved Generics in Wake of Wellington Polo Horse Deaths from Compounded Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Compound Targets, Destroys Cancer Stem Cells in Mice
(Date:1/22/2015)... Padre Murphy's and Owner Tom Boyle in ... Player Health Alliance (PPHA). The PPHA's passion for others' ... including NFL greats, treated for obstructive sleep apnea (OSA) has ... the cause in the valley. The most recent plans for ...
(Date:1/22/2015)... is a famous wedding dress company offering many trendy designs. ... Facebook, Twitter, and Pinterest. The fans will have an opportunity ... every week. , Moreover, the company has extended its 2015 ... homepage for more information. , Angelweddingdress is a ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 The ... ) in the U.S. District Court, Southern District of West ... Bard, Inc. in that proceeding’s first bellwether trial. In an ... for a new trial after finding that C.R. Bard had ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 ... after Fresenius Medical Care recalled its GranuFlo and NaturaLyte ... multidistrict litigation underway in U.S. District Court, District of ... dated January 20th, the Court has remanded a case ...
(Date:1/22/2015)... released a new blog post presenting the basic features of ... an accidental death and dismemberment rider for a car insurance ... benefits if the insured dies in an accident. Accidental death ... insurance. , AD&D is not expensive and can be ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2
... of Alabama at Birmingham (UAB) Department of Pathology have ... predict which patients are more likely to develop aggressive ... shed light on the genetics that result in worse ... researchers said. In data presented April 19 at ...
... can affect language development in children, and EEG registrations ... with severe language impairment to identify more readily those ... the Sahlgrenska Academy at the University of Gothenburg. ... divided into groups. The first group comprised children with ...
... smokers in smoke-free settings, but doctors have concerns, ... tobacco giant R.J. Reynolds launched Camel Orbs, dissolvable nicotine ... for use by smokers who find themselves in smoke-free ... online edition of Pediatrics warn that the ...
... , BIRMINGHAM, Ala. Researchers at the University of ... a set of four biomarkers that will help predict ... cancer and which are not. The findings also shed ... cancer-treatment outcomes for African-Americans, compared with Caucasians, the researchers ...
... ... learn to use bioinformatics and genomics resources with the extensive tutorial suite catalog from OpenHelix. ... (PRWEB) April 19, 2010 ... a subscription to OpenHelix ( www.openhelix.com ) giving NIH scientists and staff access ...
... , ... how to age gracefully and maintain healthy skin? Here are 35 articles that cover the ... at any age, makeup tips for mature skin and the details on effective ingredients. ... (PRWEB) April 19, 2010 -- ...
Cached Medicine News:Health News:UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis 2Health News:Language dysfunction in children may be due to epileptic brain activity 2Health News:Kids Could Overdose From Nicotine-Laced 'Candy' 2Health News:UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis 2Health News:National Institutes of Health subscribes to OpenHelix training portal 2Health News:National Institutes of Health subscribes to OpenHelix training portal 3Health News:Anti-Aging Handbook: Top 35 Articles on Treating and Preventing Signs of Aging 2Health News:Anti-Aging Handbook: Top 35 Articles on Treating and Preventing Signs of Aging 3Health News:Anti-Aging Handbook: Top 35 Articles on Treating and Preventing Signs of Aging 4
(Date:1/23/2015)...  iMD Companies, Inc. (ICBU) has repositioned itself as a holding ... a foothold in the hydroponic, hemp and medical marijuana sectors. ... in the sector, and recently partnering with the Chippewa Tribe ... medical marijuana, iMD is committing to bring its vision to ...
(Date:1/23/2015)... MONMOUTH JUNCTION, N.J. , Jan. 23, 2015 ... immunotherapy company commercializing its CytoSorb® extracorporeal cytokine adsorber ... surgery patients, announced the receipt of $385,642, net ... approved participant of the Technology Business Tax Certificate ...
(Date:1/23/2015)... Tianyin Pharmaceutical Inc. (NYSE Amex: TPI ), ... sale of patented biopharmaceutical medicine, modernized traditional Chinese medicine ... announced the business and development progress at its Jiangchuan ... the September 2014 JCM application (No. 51268) for the ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4
... Modulator Administered in Dual Cord Blood Transplant for Hematologic MalignancyLA ... announced today that the first patient has been ... small molecule Stem Cell Modulator (SCM) designed to increase hematopoietic ... key pathways that guide cell fate. The study, which ...
... delivers Germ-Free cleaning, extending life, efficiency and healthiness of ... are almost neurotic about washing their hands and using ... at their computer and put their hands all over ... ground for these persistent little bugs, which are known ...
Cached Medicine Technology:Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 2Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 3Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 4GreenBytes Wards Off Germs and Costly Computer Repairs 2GreenBytes Wards Off Germs and Costly Computer Repairs 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: