Navigation Links
Comparable patterns of failure between SBRT, lobectomy or pneumonectomy for stage I NSCLC
Date:1/15/2013

DENVER For patients with medically operable clinical stage I nonsmall-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy (SBRT) has become a standard of care. Researchers from the Washington University School of Medicine wanted to compare the patterns of failure (primary tumor control, local control, regional control, and distant control) between each method.

A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, concludes that there are comparable patterns of failure between treatments.

Researchers looked at 454 patients (336 surgery, 118 SBRT) treated at Washington University in St. Louis between January 2004 and January 2008. The results demonstrate that patterns of failure between optimal surgery (lobar resection) and optimally dosed SBRT are similar. However, their results also highlight the difficulties in making such comparisons, given the inherent imbalance in both patient and tumor-related factors. For example, lobar resection patients were younger, healthier, and had superior pulmonary function, while more patients in the SBRT group had smaller tumors.

While researchers were unable to control for factors predictive of overall survival, they were able to match 76 patients in each group based on tumor size. Researchers noted, "In a T-stage matched comparison of 152 patients, there was no significant difference in patterns of failure or cancer-specific survival"

They conclude that, "In this retrospective comparison, overall survival was superior for surgery, though cancer-specific survival was similar. Randomized trials are necessary to control for fundamental differences in co-morbidity that impact interpretation of both tumor control and survival."


'/>"/>

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related medicine news :

1. Infection data may not be comparable across hospitals, study shows
2. Cancer screening rates comparable for those with and without rheumatoid arthritis
3. Head-to-head study in RA shows that abatacept has comparable efficacy to adalimumab
4. Laser-light testing of breast tumor fiber patterns helps show whose cancer is spreading
5. New software helps reveal patterns in space and time
6. Birds Songs Reflect Changing Weather Patterns: Study
7. Menstrual Cycles May Affect Womens Shopping Patterns
8. Obesity genes may influence food choices, eating patterns
9. WSU researches patterns of heavy alcohol use and life commitments in at-risk young adults
10. US Drug Watchdog Now Urges Victims of a Transvaginal Mesh Product Failure To Get Some Meaningful Help From Women Attorneys Who Understand This Horrific Mess and the Costs
11. US Drug Watchdog Is Now Open All Weekends To Help Victims Of A Transvaginal Mesh Product Failures With A Service That Includes Naming Top Attorneys--Who Are All Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
Breaking Medicine Technology: