Navigation Links
Comparable patterns of failure between SBRT, lobectomy or pneumonectomy for stage I NSCLC
Date:1/15/2013

DENVER For patients with medically operable clinical stage I nonsmall-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy (SBRT) has become a standard of care. Researchers from the Washington University School of Medicine wanted to compare the patterns of failure (primary tumor control, local control, regional control, and distant control) between each method.

A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, concludes that there are comparable patterns of failure between treatments.

Researchers looked at 454 patients (336 surgery, 118 SBRT) treated at Washington University in St. Louis between January 2004 and January 2008. The results demonstrate that patterns of failure between optimal surgery (lobar resection) and optimally dosed SBRT are similar. However, their results also highlight the difficulties in making such comparisons, given the inherent imbalance in both patient and tumor-related factors. For example, lobar resection patients were younger, healthier, and had superior pulmonary function, while more patients in the SBRT group had smaller tumors.

While researchers were unable to control for factors predictive of overall survival, they were able to match 76 patients in each group based on tumor size. Researchers noted, "In a T-stage matched comparison of 152 patients, there was no significant difference in patterns of failure or cancer-specific survival"

They conclude that, "In this retrospective comparison, overall survival was superior for surgery, though cancer-specific survival was similar. Randomized trials are necessary to control for fundamental differences in co-morbidity that impact interpretation of both tumor control and survival."


'/>"/>

Contact: Kristal Griffith
Kristal.Griffith@iaslc.org
720-325-2952
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related medicine news :

1. Infection data may not be comparable across hospitals, study shows
2. Cancer screening rates comparable for those with and without rheumatoid arthritis
3. Head-to-head study in RA shows that abatacept has comparable efficacy to adalimumab
4. Laser-light testing of breast tumor fiber patterns helps show whose cancer is spreading
5. New software helps reveal patterns in space and time
6. Birds Songs Reflect Changing Weather Patterns: Study
7. Menstrual Cycles May Affect Womens Shopping Patterns
8. Obesity genes may influence food choices, eating patterns
9. WSU researches patterns of heavy alcohol use and life commitments in at-risk young adults
10. US Drug Watchdog Now Urges Victims of a Transvaginal Mesh Product Failure To Get Some Meaningful Help From Women Attorneys Who Understand This Horrific Mess and the Costs
11. US Drug Watchdog Is Now Open All Weekends To Help Victims Of A Transvaginal Mesh Product Failures With A Service That Includes Naming Top Attorneys--Who Are All Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... ... Wellness (IFW) Program at Reproductive Medicine Associates of Connecticut (RMACT). McLaughlin brings nearly ... team of three acupuncturists to help patients realize their family building goals. ...
(Date:12/7/2016)... ... December 07, 2016 , ... “Walking With God: Inspirational Lessons from ... inspire the reader to be aware of God's direction in their lives. “Walking With ... Smith, retired teacher and active church leader. , Sanford says, “I enjoy ...
(Date:12/7/2016)... ... December 07, 2016 , ... The Business ... Summit in Reston, VA on March 21-22, 2017. This premier event features business ... experiences from a cross-section of industries such as financial services, insurance, healthcare, manufacturing, ...
(Date:12/7/2016)... York (PRWEB) , ... December 07, 2016 , ... "Hacking ... at Yale had described him as 'a genius.'" Thus begins "Margaret in Berlin," Book ... Rhyse and published by Wyston Books, Inc. These novels narrate the lives ...
(Date:12/6/2016)... ... December 06, 2016 , ... Men with gum disease are ... serious health problems, such as cardiovascular illness, according to research cited in a ... Periodontics & Dental Implant Center notes that the correlation between periodontal disease and ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... , Dec. 6, 2016 Eurofins ... accreditation from the College of American Pathologists (CAP) ... (CLIA) for its new laboratory in ... moved its North American headquarters. "Our ... sequencing -- which is still considered the ,Gold ...
(Date:12/6/2016)... , Dec. 6, 2016  BTL Aesthetics today ... that its BTL Vanquish ME device was effectively ... delivery to the targeted tissue. The result: Significantly ... higher, with BTL Vanquish ME versus BTL Vanquish. ... physician network and their patients with the most ...
(Date:12/6/2016)... 6, 2016   Sienna Biopharmaceuticals, Inc. ... and aesthetics company, today announced it has ... pharmaceutical company focused on developing first-in-class topical ... psoriasis, atopic dermatitis and pruritus (itch). Under ... make an undisclosed upfront payment in cash ...
Breaking Medicine Technology: