Navigation Links
Commonly used medications associated with impaired physical function in older adults
Date:5/3/2008

WINSTON-SALEM, N.C. Older adults who take drugs designed to block the neurotransmitter acetylcholine including common medications for incontinence, high blood pressure and allergies are more likely to be dependent in one or more activities of daily living and to walk slower, according to new findings from researchers at Wake Forest University School of Medicine and colleagues.

The findings, which involve a class of drugs known as anticholinergic medications, are from the Ginkgo Evaluation of Memory Study (GEMS) and will be presented at the American Geriatrics Society Meeting in Washington, D.C., on May 3.

These results were true even in older adults who have normal memory and thinking abilities, said Kaycee M. Sink, M.D., M.A.S., lead author. For older adults taking a moderately anticholinergic medication, or two or more mildly anticholinergic medications, their function was similar to that of someone three to four years older.

In a separate study reported this month in the Journal of the American Geriatrics Society, Sink found that older nursing home residents who took medications for dementia and anticholingeric medications for incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia.

Over a years time, the decline would represent a resident going from requiring only limited assistance in an activity to being completely dependent, or from requiring only supervision to requiring extensive assistance in an activity.

Sink said that the two studies together suggest that physicians should carefully consider the implications when prescribing anticholingeric medications to older adults.

Because these medications are so commonly prescribed, older adults who take multiple medications are at increased risk of taking one or more anticholinergic-containing medications, said Sink. The potential effects on physical function represent a significan
'/>"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
Source:Eurekalert

1

GOOD

Page: 1 2

Related medicine news :

1. Phase III Trial of VELCADE(R) (Bortezomib) for Injection Showed Dramatic Fourfold Increase in Complete Remission Rates When Combined With the Most Commonly Used U.S. Regimen in Front-Line Multiple Myeloma
2. New U of C research examines commonly used toxin
3. Cells on path to becoming mature T-cells more flexible than commonly thought
4. AHRQ and FDA to Collaborate in Largest Study Ever of Possible Heart Risks with ADHD Medications
5. Diet and medications may assist prevention of prostate cancer
6. Cautious Optimism for New Alzheimers Medications, Reports the Harvard Mental Health Letter
7. Patients cant recall their medications to tell doctors
8. The American Pharmacists Association Supports Consumer Education About OTC Medications
9. Combining Medications Often Best Strategy to Battle Rheumatoid Arthritis
10. Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best
11. Cost of glaucoma medications may impact treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2008)...24 /PRNewswire/ -- MediVoice(R), LLC, the,world,s ...h and,e-Prescribing, has formed a strategic partne...teractive, web-based, patient-centered health reco...o integrate and market its,mobile voice-activation...OC) system., "MediVoice is pleased to develop a s...
(Date:7/23/2008)...wswire/ -- Philip J. Dwyer, president and CEO,of t...ny before the U.S.,Senate Health, Education, Labor... and Families today to call for increased funds fo...nted at YMCAs across the nation, that will,help re...e on behalf of the more than 2,600 YMCAs, that -- ...
(Date:7/23/2008)...migration and Naturalization ready at Passport ...uly 23 /PRNewswire/ -- New vaccine requirements wi...visa for entry into the U.S. and,anyone seeking ad...ants,must show proof of vaccinations against vacci.... Advisory Committee on Immunization Practices.,Pa...
(Date:7/23/2008)...008) Biodiversity has long been recognized by EPA ...rely on healthy ecosystems to provide food, clean ...he connection between disease and biodiversity (th...n a geographic region). Recent studies suggest th... diseases such as Lyme disease and West Nile encep...
Breaking Medicine News(10 mins):Health News:MediVoice(R) Partners With VisionTree(R) to Integrate Its Voice-Activated e-Prescribing Solution Into VisionTree's VTOC(TM) Web-Based Patient Management System 2Health News:MediVoice(R) Partners With VisionTree(R) to Integrate Its Voice-Activated e-Prescribing Solution Into VisionTree's VTOC(TM) Web-Based Patient Management System 3Health News:YMCA Calls on Senate to Fund Community-Based Solutions to Address Childhood Obesity Crisis 2Health News:YMCA Calls on Senate to Fund Community-Based Solutions to Address Childhood Obesity Crisis 3Health News:USCIS Tightens Vaccination Requirements 2Health News:Could preserving biodiversity reduce disease? 2
...ow dietary recommendations contained in tools like... been deveoped by researchers at the University of...erence to the recommendations decreases as the chi...of the study were to develop and test the potentia...
...icide permethrin can reduce the chances of malaria... conclusion was arrived at after Elizabeth Kimani ...er in Nairobi and other researchers studied Somali... in Kenya. The average household size in Kenya i...
...till fresh in the memory. There are a whole lot of...dequate measure’ is considered extremely crucial./... has extended this sentiment in evolving suitable ... onslaught. In the following week, Thai and Germa...
...wel complaint, now faces the risk of losing his le...l. // His left foot became infected when he was be...e was sent home, but returned four months later on... "I've been told I'm on the point of losing my le...
Other Medicine News:Health News:Adherence to Dietary Recommendations Measured 2Health News:Adherence to Dietary Recommendations Measured 3
(Date:7/23/2008)...uly print edition of Clinical ...23 /- A Roche Diagnostics-sponsored,p...type natriuretic peptide,(NT-proBNP) confirms the ...on in predicting the risk of cardiovascular advers...oidal anti-inflammatory drugs of,the COX inhibitor...
(Date:7/23/2008)... InCode BioPharmaceutics, Inc.,an emerging biopha...est,results demonstrating the utility of their lea...re chronic blood disorder paroxysmal nocturnal,hem...esented at the XXII,International Complement Works...he only treatment currently available for PNH pati...
(Date:7/22/2008)...onin Medical, a leading innovator,of physiological...entered,the clinical testing phase with its breakt...ation. Today,s most common application for this,te...nal blood oxygenation,in the brain -- cerebral oxi...ngoing clinical study at the,Duke University Medic...
(Date:7/22/2008)...idra(R) Resulted in Significant, Reductions in A1C...gorithm Used, BR...rom the "Adjust to,Target in Type 2 Diabetes: Comp...ing for Adjustment of Mealtime Insulin Glulisine" ...ociation,s (ADA) medical journal,Diabetes Care. T...
Breaking Medicine Technology:Study Reveals Potential for NT-proBNP as a Marker to Predict Cardiovascular Risks From Anti-Inflammatory Drugs 2Study Reveals Potential for NT-proBNP as a Marker to Predict Cardiovascular Risks From Anti-Inflammatory Drugs 3Study Reveals Potential for NT-proBNP as a Marker to Predict Cardiovascular Risks From Anti-Inflammatory Drugs 4InCode BioPharmaceutics, Inc. Announces Key Data Supporting New Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) 2Nonin Medical Inc. Announces Entry Into the Cerebral Oximeter Market 2Newly Published Study Results Showed That Two Mealtime Insulin Dosing Algorithms Were Effective for Patients with Type 2 Diabetes 2Newly Published Study Results Showed That Two Mealtime Insulin Dosing Algorithms Were Effective for Patients with Type 2 Diabetes 3Newly Published Study Results Showed That Two Mealtime Insulin Dosing Algorithms Were Effective for Patients with Type 2 Diabetes 4Study aims to improve sex education for deaf pupils 21604 1Study aims to improve sex education for deaf pupils 21604 2Study aims to improve sex education for deaf pupils 21604 3Lupin Launches Ramipril Capsules 21601 1Lupin Launches Ramipril Capsules 21601 2Lupin Launches Ramipril Capsules 21601 3CVS Caremark Launches the 2008 Season of the CVS Caremark All Kids Can 28TM 29 Baseball Camps at Fenway Park 21598 1CVS Caremark Launches the 2008 Season of the CVS Caremark All Kids Can 28TM 29 Baseball Camps at Fenway Park 21598 2Hunter Tylo of CBS The Bold and The Beautiful Joins Forces With the American Epilepsy Outreach Foundation in Public Awareness Campaign 21595 1Hunter Tylo of CBS The Bold and The Beautiful Joins Forces With the American Epilepsy Outreach Foundation in Public Awareness Campaign 21595 2Hunter Tylo of CBS The Bold and The Beautiful Joins Forces With the American Epilepsy Outreach Foundation in Public Awareness Campaign 21595 3
...HAMBURG, Germany, May 03, 2007 /PRNewswire/ -- At ... data which provide a sound,scientific basis for a...n patients. , Tumor tissue-derived primary cell li... testing. During their clonal selection and,expans...tterns,change significantly, thereby losing many o...
...BOSTON, May 03, 2007 /PRNewswire/ -- Bayer HealthC... three clinical,studies with Betaseron(R) (interfe...Academy of Neurology,s (AAN) 59th Annual Meeting,...ty, and high,patient satisfaction with treatment i...sis (MS). , "Collectively, these studies highlight...
Other Medicine Technology:Indivumed Study Provides Sound Scientific Basis for a Predictive,Drug Test- Platform 2Studies Presented at Neurology Conference Highlight Early Efficacy,Long-Term Tolerability, and High Patient Satisfaction with,Betaseron 2Studies Presented at Neurology Conference Highlight Early Efficacy,Long-Term Tolerability, and High Patient Satisfaction with,Betaseron 3Studies Presented at Neurology Conference Highlight Early Efficacy,Long-Term Tolerability, and High Patient Satisfaction with,Betaseron 4
...atory and a worldwide leader in innovative laborat...sive test menu of highly complex and unique medica...by the University of Utah, ARUP Laboratories' clie...ity teaching hospitals and children's hospitals, m...
...atory and a worldwide leader in innovative laborat...sive test menu of highly complex and unique medica...by the University of Utah, ARUP Laboratories' clie...ity teaching hospitals and children's hospitals, m...
...atory and a worldwide leader in innovative laborat...sive test menu of highly complex and unique medica...by the University of Utah, ARUP Laboratories' clie...ity teaching hospitals and children's hospitals, m...
...atory and a worldwide leader in innovative laborat...sive test menu of highly complex and unique medica...by the University of Utah, ARUP Laboratories' clie...ity teaching hospitals and children's hospitals, m...
Medicine Products: