Navigation Links
Commonly used drug can limit radiation damage to lungs and heart for cancer patients
Date:4/21/2013

Geneva, Switzerland: Unavoidable damage caused to the heart and lungs by radiotherapy treatment of tumours in the chest region can be limited by the administration of an ACE inhibitor, a drug commonly used in the treatment of cardiovascular disease, a group of Dutch researchers have found. [1]

Common cancers such as breast, oesophagus, lung, and Hodgkin's lymphoma are frequently treated with radiotherapy, but the radiation dose that can be given safely is limited by the sensitivity of the health lung tissue which is also irradiated.

The lung is a particularly complex and sensitive organ and strategies for protecting it from radiotherapy damage, apart from limiting the dose given and, therefore, the efficacy of the treatment, are few. Presenting the research to the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO) today (Sunday), Dr Sonja Van der Veen, MSc, from the University Medical Centre, Groningen, The Netherlands, said that she had set out with colleagues to see whether the use of an ACE inhibitor could protect against early radiation-induced lung toxicity (RILT). Previous studies had shown that damage to blood vessels can play an important role in the development of RILT [2], so the researchers irradiated the lungs, heart, or heart and lungs of rats and administered the ACE inhibiter captopril immediately after treatment. The rats' lung functions were then measured at two-weekly intervals.

"After eight weeks, when early lung toxicity is usually at its height, we found that captopril improved the rats' heart and lung functions, but we were surprised to find that this only occurred when the heart was included in the irradiation field," said Dr Van der Veen. "This was not due to protection of the lung blood vessels, which were equally damaged with or without captopril. So we investigated further and found that the captopril treatment improved the heart's function and decreased the level of fibrosis in the he
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society for Radiotherapy and Oncology (ESTRO)
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Commonly used cholesterol calculation underestimates heart disease danger for many
2. UV Flash Infection Control Unit Steps onto the Healthcare Market, with a Quick and Effective Way to Disinfect Virtually any Item Commonly Found in Medical Facilities
3. New UAlberta research shows commonly prescribed medications could have adverse effects
4. Condition Commonly Seen in Aging May Alter Brain Function
5. Commonly used painkillers may protect against skin cancer
6. Memory, the adolescent brain and lying: The limits of neuroscientific evidence in the law
7. Career Confidential Announces Their Cover Letter Podcast Viewing Complimentary for a Limited Time
8. Asia-Pacific Seasonal Influenza Vaccine Market to 2018 - Positive Impact of Government Support Offset by Limited Production Capacity : MarketResearchReports.biz
9. Ability to think about thinking not limited to humans
10. iPad Ultra Thin Aluminum Bluetooth Keyboard Case Released by iGearUnlimited
11. Kwiksure Discovers Uses and Limitations of Vehicle GPS in Hong Kong
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... (PRWEB) November 27, 2014 Blood-borne pathogens ... many medical precautions and procedures in place to counter ... and disposal of things tainted with menstrual blood are ... design a simpler, more sanitary way to handle tampons ... an inventor from Sonora, Calif. , He then created ...
(Date:11/27/2014)... Dotinga HealthDay Reporter , WEDNESDAY, ... pre-wired to acquire a second language, new research suggests. But ... likely gain a brain boost, the small study finds. ... said study co-author Ping Li, co-director of the Center for ... even more interesting, Li said, that "the brain networks of ...
(Date:11/27/2014)... PITTSBURGH, PA (PRWEB) November 27, 2014 In ... an inventor from Sharpes, Fla., designed an easy way to ... lowering it/them. , He then created a prototype of the ... lift or lower a toilet seat and/or lid in a ... which prevents the spread of germs. Overall, it promotes good ...
(Date:11/27/2014)... November 27, 2014 Tylenol lawsuits ( ... allegedly injured by the medication are continuing to move ... is looking ahead to a status conference in December, ... Scheduling Order issued earlier this year, a conference in ... at 10:00 a.m. Items likely to be discussed at ...
(Date:11/27/2014)... DC (PRWEB) November 27, 2014 “LAB.C” was ... which features the latest and coolest technology products available to ... conducted the product review and shared with viewers ... for iOS and Android devices. , Consumers love portability and ... Their Cable Case for the iPhone5 and 5S has ...
Breaking Medicine News(10 mins):Health News:Some People May Be Pre-Wired to Be Bilingual 2Health News:Some People May Be Pre-Wired to Be Bilingual 3Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:Top Mobile Friendly Accessories were Featured on NewsWatch Television on October 30, 2014 2
... be more effective than a "fat" tax for deterring overweight ... study has found. A survey of 364 shoppers in random ... people from reaching for junk food, shoppersincluding those with the ... high fat content and included a note that the item ...
... D.C. It is important that the United States begin to ... APS believes that as a nation we need to be smart ... a clear understanding of what it means for America,s future jeopardizes ... For more than half a century, science and technology have been ...
... (HealthDay News) -- A lack of leptin contributes to the ... of body fat, but treatment with a synthetic form of ... a new study indicates. Extremely low levels of body ... as runners and dancers, and in those with eating disorders. ...
... April 8, 2011 Increased levels of a protein ... a major cardiovascular event in high-risk patients, according to a ... Measuring the amount of the protein, known as plasma renin ... tool to assess a patient,s risk and help prevent a ...
... HealthDay Reporter , THURSDAY, April 7 (HealthDay ... stroke appears to promote arm strength and function, Canadian ... approaches -- including the use of virtual reality [gaming] ... social participation," said lead researcher Dr. Gustavo Saposnik, director ...
... 2011A growing body of research suggests that caffeine disrupts ... poor control of type 2 diabetes, a major public ... of Journal of Caffeine Research : The International ... from Mary Ann Liebert, Inc. publishers, examines the latest ...
Cached Medicine News:Health News:Warning labels better than a fat tax, University of Alberta study shows 2Health News:US House budget plans would jeopardize scientific research facilities 2Health News:Hormone Linked to Absence of Periods in Women With Low Body Fat 2Health News: Video Games Might Aid in Stroke Rehab 2Health News: Video Games Might Aid in Stroke Rehab 3Health News:Caffeine and diabetes -- helpful or harmful? 2
(Date:11/26/2014)... PORTLAND, Oregon , November 26, 2014 ... or fascia of the organ protrudes through the wall of ... weak muscle area at birth are some of the causes ... inguinal, umbilical, hiatal, femoral, and incisional. An inguinal hernia is ... area. An umbilical hernia is found in the area of ...
(Date:11/26/2014)... YORK , Nov. 26, 2014 ... growing at a rate of 4%, with world ... to Kalorama Information. MRI and other types of ... diagnosis and treatment of numerous medical conditions in ... technologies and techniques. Kalorama,s report, Medical Imaging ...
(Date:11/26/2014)... SAN FRANCISCO , Nov. 25, 2014  goBalto, ... solutions, has been recognized as a winner of Red ... received a Global Top 100 North America award in ... the international technology landscape. Red Herring,s Top ... for identifying promising new companies and entrepreneurs. Red Herring ...
Breaking Medicine Technology:Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 2Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 3Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 4Kalorama: Steady Growth in the Medical MRI Market 2Kalorama: Steady Growth in the Medical MRI Market 3goBalto Selected as a 2014 Red Herring Top 100 Global Company 2goBalto Selected as a 2014 Red Herring Top 100 Global Company 3
... SAN DIEGO, April 25, 2011 Pharmatek Laboratories, ... supporting the pharmaceutical industry, announced that it has ... manufacturing capabilities.  The company has purchased a Buchi ... and small-scale clinical manufacture.  This technology can be ...
... Uroplasty, Inc. (NASDAQ: ... manufactures and markets innovative proprietary products to treat ... clinical studies using Uroplasty,s Urgent® PC Neuromodulation System ... to be presented at three upcoming professional meetings. ...
Cached Medicine Technology:Pharmatek Laboratories Adds Spray Drying to Drug Development Services 2Clinical Studies Results of Uroplasty Products Scheduled for Presentation at Three Professional Meetings 2Clinical Studies Results of Uroplasty Products Scheduled for Presentation at Three Professional Meetings 3
SHIONORIA BNP,is a reagent used in the measurement of blood BNP. The blood BNP test allows accurate estimation of coronary functions....
... assay method for the semi-quantitative determination ... in human serum. The results of ... as an aid in the diagnosis ... associated with elevated anti-neutrophil cytoplasmic antibodies ...
... determination of Ang II is ... the pharmacological effect and efficiency ... angiotensin converting enzyme inhibitors (ACE ... antagonists as well as for ...
... The SAS RSV antigen ... rapid assay for the presumptive ... antigen directly from nasopharyngeal specimens ... This one-step 15 minute test ...
Medicine Products: