Navigation Links
Common vein condition increases risk for developing life-threating blood clots

(WASHINGTON, August 17, 2011) Patients with clinically diagnosed superficial vein thrombosis (SVT), a blood clot in the veins just beneath the skin that commonly resolves on its own without treatment, are four to six times more likely to develop venous thromboembolism (VTE), a dangerous, often life-threatening condition, according to study results published today in Blood, the Journal of the American Society of Hematology (ASH).

Recent studies have shown that patients diagnosed with SVT using ultrasound to confirm the presence of a clot showed increased risk of VTE; however, it was unclear whether patients with "clinically diagnosed" (without the use of ultrasound) SVT also had an increased risk for VTE.

"While current literature defines 'real' SVT as a disorder diagnosed both clinically and through an ultrasound, in reality, clinical practice does not necessarily follow this model. In fact, most physicians are able to identify SVT by the presence of a red, painful, palpable cord in the course of a patient's superficial vein, for which additional testing with ultrasound is not necessary," said Suzanne C. Cannegieter, MD, PhD, senior study author and Senior Clinical Researcher in the Department of Clinical Epidemiology at Leiden University Medical Center in Leiden, Netherlands.

VTE is a clotting disorder that includes both deep-vein thrombosis (DVT) and pulmonary embolism (PE). DVT is a blood clot that typically forms in the deep veins of the leg and can develop into PE when the clot breaks free and becomes lodged in a major artery in the lung, blocking blood flow. Symptoms of PE can include sharp chest pain, rapid pulse, shortness of breath, fever, and, in extreme cases, sudden death. While symptoms of DVT can include sudden pain, swelling, and tenderness in the limbs, not everyone with DVT experiences them.

"If an undiagnosed DVT progresses to a PE, the situation can become serious very quickly. Therefore, it is extremely important to understand and recognize the risk factors for DVT," said Dr. Cannegieter.

To determine whether patients with clinically diagnosed SVT are at risk for VTE, study authors from Leiden University Medical Center analyzed questionnaire responses from 4,290 patients with VTE and 5,644 controls without VTE. Study participants were previously enrolled in the MEGA study, a large, population-based, case-control study that assessed VTE risk in nearly 5,000 patients with over 6,000 controls from six anticoagulation clinics in the Netherlands between March 1999 and September 2004. In this particular study, the authors also assessed patients on VTE risk, particularly whether they had SVT before VTE diagnosis or prior to study enrollment. Results from the study analysis revealed that SVT was prevalent in 10 percent of the VTE patients, and in two percent of the control group. All patients with prior SVT were found to be six times more likely to develop DVT and four times more likely to develop PE than controls.

"Our results, which are in line with recent studies that regard SVT diagnosed by ultrasonographs as a precursor of VTE, show that a history of clinically diagnosed SVT is a risk factor for future VTE," said Dr. Cannegieter. "We recommend that clinicians should actively ask patients for a history of clinically diagnosed SVT and use this information in their risk stratisfication analysis. Furthermore, people who experience symptoms of SVT are advised to see a doctor, particularly when these symptoms do not pass or grow worse, as SVT appears not to be a separate and benign form of venous thrombosis, as previously thought."


Contact: Lindsey Love
American Society of Hematology

Related medicine news :

1. Common themes emerge in hospitals anti-MRSA efforts: Study
2. Outbreak C. difficile strain common in Chicago hospitals, investigation finds
3. Common class of pain drugs reduces severity of postpartum breast cancers
4. Peak oil and public health: Political common ground?
5. Johns Hopkins scientists map genes for common form of brain cancer
6. Scientists May Have Found Missing Link to Common Brain Cancer
7. Common Swimming Injuries Often Avoidable
8. University of Maryland researchers discover possible drug targets for common non-Hodgkins lymphoma
9. RI Hospital researchers find common test may be unnecessary for bariatric surgery candidates
10. No increase in commonest preventable cause of intellectual disability over 20 years
11. Exposure to Common Chemicals May Affect Thyroid Function
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... Element Blue ... introduced a new company, RightSensor™ LLC, an Internet of Things (IoT) hardware supplier ... provides a fully-managed approach for customers requiring sensor hardware for critical data environments. ...
(Date:10/13/2015)... ... 13, 2015 , ... Relay (, a technology company that ... significant contract that will provide its award-winning private messaging solution to Independence Blue ... success of its Relay program, IBX Wire™, which now has over 550,000 members ...
(Date:10/13/2015)... ... October 13, 2015 , ... e-con Systems Inc., a leading embedded design ... the industry’s first RGB-IR pixel format camera with a USB 3.0 interface and ... See3CAM family of UVC USB 3.0 cameras, is based on the 1/3-inch OV4682 - ...
(Date:10/13/2015)... Tenn. (PRWEB) , ... October 13, 2015 , ... A ... and that’s why SmileCareClub , the leading remote invisible aligner system, has joined ... who would otherwise go without it. For each aligner treatment plan purchased, SmileCareClub will ...
(Date:10/13/2015)... ... October 13, 2015 , ... Protein is essential to good health. You ... and blood. But how much protein does the average man need in order to ... to the October 2015 issue of Harvard Men's Health Watch . Most Americans ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... , Oct. 13, 2015   Micell Technologies ... DESSOLVE I and II trials of its MiStent Sirolimus ... ® ) were presented at the 27th Annual ... San Francisco , October 11-15. TCT ... cardiovascular medicine. MiStent SES was designed to optimize vessel ...
(Date:10/13/2015)... -- Health Gorilla ( ) today announced the launch ... secure platform for clinical data and communications poised to change ... healthcare in the US. The launch follows the closing of ... of $4.4M raised to date, with Data Collective ... Harris Barton , Orfin Ventures and ...
(Date:10/13/2015)... 2015 China Jo-Jo Drugstores, Inc. ... "), a leading China-based retail, wholesale and online distributor ... online and retail pharmacies, announced preliminary half year fiscal ... pharmacy through , growing 438% year over ... China Jo-Jo,s online sales are ...
Breaking Medicine Technology: