Navigation Links
Common osteoporosis drugs are associated with a decrease in risk of breast cancer
Date:3/2/2010

SEATTLE Women who take some types of bone-building drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a study by U.S. researchers published today in the British Journal of Cancer.

The study found that women who used bisphosphonate drugs, such as Fosamax, Boniva and Zomita, for more than two years had a nearly 40 percent reduction in risk as compared to those who did not, according to lead author Polly Newcomb, Ph.D., M.P.H., head of the Cancer Prevention Program at Fred Hutchinson Cancer Research Center.

"This large study provides new evidence that the use of bisphosphonates is associated with a potentially important reduction in breast cancer risk," Newcomb said.

The protective effect was observed only among women who were not obese. "Obese women may have elevated estrogen levels, so underlying hormones may influence the ability of bisphosphonates to reduce breast cancer risk," Newcomb said.

The way in which these drugs may prevent breast cancer is not known, but several research observations may be relevant. "These drugs may affect cell function and be important in cell growth and death specifically the death of tumors or even premalignant disease," Newcomb said. Researchers have found that some kinds of bisphosphonates directly cause tumor apoptosis (cellular suicide), inhibit angiogenesis (prevent tumors from establishing a blood supply) and prevent tumor-cell adhesion (the ability of cancer cells to bind to one another).

The study involved nearly 6,000 Wisconsin women, aged 20 to 69. Half had been diagnosed with invasive breast cancer and, for comparison purposes, half had not. The women were interviewed about their bone health their history of fractures, whether they'd been diagnosed with osteoporosis and their history of bisphosphonate use.

Breast cancer risk factors such as first-degree family history of the disease, age at first birth, postmenopausal hormone use and body m
'/>"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
2. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
3. Contrast-enhanced MRI could play a key role in differentiating between common types of arthritis
4. Migraine More Common in Women with MS
5. New therapeutic target for most common solid cancer in childhood?
6. US21, Inc. is Granted a Wholesale Distributor Permit from the Commonwealth of Virginia Board of Pharmacy
7. U.S. National Guard Connects Nationwide with Desktop Alert's Command and Control Mass Notification Systems and Common Alerting Protocol (CAP)
8. A common cholesterol drug fights cataracts, too
9. Adapting to clogged airways makes common pathogen resist powerful drugs
10. Metabolite common among cancers
11. Nutrition Management Services Company Announces Decision to Deregister its Class A Common Stock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... August 01, 2015 , ... On March 19, 2015 Phil Valentine – the Executive Director ... Appalachian Trail by stepping off Springer Mountain and heading north. Since that day, ... Phil reached Connecticut and was greeted by friends and family. He visited CCAR and ...
(Date:7/31/2015)... Clara, CA (PRWEB) , ... August 01, 2015 , ... Super Bowl 50 ... The National Football League’s biggest day each year is the Super Bowl. In the two ... that takes place from the host venue. The 2016 Super Bowl game will mark the ...
(Date:7/31/2015)... ... 31, 2015 , ... The 2nd annual Ride to Fight On will start ... 3, 2015. The Ride to Fight On is a cycling fundraiser that benefits the ... West Clinic and The University of Tennessee Health Science Center. A health and wellness ...
(Date:7/31/2015)... , ... July 31, 2015 , ... Coco Libre announced ... judges, media, and VIPs at the 2015 Vans US Open of Surfing, July 25 ... that can claim “no added sugar” on the market, is a natural choice given ...
(Date:7/31/2015)... ... July 31, 2015 , ... Well-known for its unique pastries ... wedding cakes with custom designs, making life just a little bit sweeter for ... cakes for each customer who orders one. , The bakery provides a full line ...
Breaking Medicine News(10 mins):Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2
... , DURHAM, N.C., Sept. 22 Oxygen Biotherapeutics, ... Chris Stern, will present at an investor conferences in Zurich on Sept. ... the Zurich Airport Radisson Hotel and is scheduled for 7:00 p.m. The ... interested investors. , , About Oxygen Biotherapeutics, ...
... , , WILMINGTON, ... ), a dermatology company that is developing and marketing Levulan(R) Photodynamic ... conditions, announced that Bob Doman, President and Chief Executive Officer, will ... Conference on Tuesday, September 29, 2009 at 10:30 a.m. ET at ...
... FALLS CHURCH, Va., Sept. 22 ... the successful implementation of the first phase of Fletcher Allen ... Record and Information Systems Management), after a 15-month planning and ... areas as well as the Emergency Department, Walk-In Care Center, ...
... have boosted seniors, sexually transmitted infection rates, researchers say ... who recently lost their wives are more likely to ... are still married, a new study has found. ... like Viagra could boost the risk, noting the widowers ...
... , Changes Reflect Provisions in NAIC Model Act ... URAC , a leading health care accreditation and education organization, ... changes to its Independent Review Organization (IRO) Standards, Version 4.1. Purchasers, policy ... to provide their comments on t he proposed URAC standards ...
... , SAN DIEGO, Sept. 22 ... a Benefit Concert for Dystonia on Saturday, October 3, 2009 at ... , , Dystonia is a devastating neurological ... in various muscle groups of the body. Some forms are focal ...
Cached Medicine News:Health News:CSC Helps Fletcher Allen Health Care Implement Phase One of Electronic Health Records System in 15 Months 2Health News:CSC Helps Fletcher Allen Health Care Implement Phase One of Electronic Health Records System in 15 Months 3Health News:Sex With New Partners Raises Widowers' Disease Risk 2Health News:URAC Open Public Comment Period for New Independent Review Organization Standards 2Health News:URAC Open Public Comment Period for New Independent Review Organization Standards 3Health News:Juice Newton Performs Benefit Concert to Support Dystonia Research 2
(Date:7/31/2015)... LAKE, N.J. and SAN DIEGO ... today that its parent company Eisai Co., Ltd. (Headquarters: ... Haruo Naito , "Eisai") and Halozyme Therapeutics, Inc. (Headquarters: ... CEO: Dr. Helen Torley , "NASDAQ: HALO") have ... mesylate (brand name: Halaven ® , "eribulin") in combination ...
(Date:7/31/2015)... 2015 Magnaquest, a leading ... and cloud computing operators has signed a Proof ... for Internet of Things (IoT) related initiative. The ... subscription model.      (Logo: http://photos.prnewswire.com/prnh/20140807/700645 ... for business innovations to make healthcare services more ...
(Date:7/30/2015)... DIEGO , July 30, 2015 /PRNewswire/ ... it has signed a definitive agreement to ... of non-invasive ventilation and sleep-disordered breathing medical ... clinical, innovation and market reputation in China, combined with ResMed,s global leadership in ... people in China ...
Breaking Medicine Technology:Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 2Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 3Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 4Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 5Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 6Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... Remedi SeniorCare®, one of the nation,s largest ... innovative solution for the long-term care industry -- ... long-term care facilities to more efficiently and ... This includes complex medication orders, electronic health ...
... 2012 Span-America Medical Systems, Inc. (NASDAQ:  SPAN) will ... conference call on Friday, February 3, 2012, covering results ... released after the regular close of trading the preceding ... call will be available online at www.spanamerica.com ...
Cached Medicine Technology:Connexit™ Launch Aims to Reshape Business of Long-Term Care 2Connexit™ Launch Aims to Reshape Business of Long-Term Care 3
... unique fiberoptic laryngoscope blade that can give ... needed during difficult intubations. The articulating tip ... to be raised by squeezing a lever ... produces a more complete exposure of the ...
... laryngoscope handles can be used with Portex® ... sturdy chrome blades with long-lasting bronze fiber-optic ... for continuous routine use., ,The laryngoscope ... of sizes, from infant to large adult, ...
... handles can be used with Portex® reusable ... chrome blades with long-lasting bronze fiber-optic bundles ... continuous routine use., ,The laryngoscope blades ... sizes, from infant to large adult, and ...
... an innovative intubation system. Providing an unobstructed ... is ideal for many types of intubations., ... embedded within the patented Glidescope blade. Clear ... displayed on a monitor screen. An LED ...
Medicine Products: