Navigation Links
Common osteoporosis drugs are associated with a decrease in risk of breast cancer
Date:3/2/2010

SEATTLE Women who take some types of bone-building drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a study by U.S. researchers published today in the British Journal of Cancer.

The study found that women who used bisphosphonate drugs, such as Fosamax, Boniva and Zomita, for more than two years had a nearly 40 percent reduction in risk as compared to those who did not, according to lead author Polly Newcomb, Ph.D., M.P.H., head of the Cancer Prevention Program at Fred Hutchinson Cancer Research Center.

"This large study provides new evidence that the use of bisphosphonates is associated with a potentially important reduction in breast cancer risk," Newcomb said.

The protective effect was observed only among women who were not obese. "Obese women may have elevated estrogen levels, so underlying hormones may influence the ability of bisphosphonates to reduce breast cancer risk," Newcomb said.

The way in which these drugs may prevent breast cancer is not known, but several research observations may be relevant. "These drugs may affect cell function and be important in cell growth and death specifically the death of tumors or even premalignant disease," Newcomb said. Researchers have found that some kinds of bisphosphonates directly cause tumor apoptosis (cellular suicide), inhibit angiogenesis (prevent tumors from establishing a blood supply) and prevent tumor-cell adhesion (the ability of cancer cells to bind to one another).

The study involved nearly 6,000 Wisconsin women, aged 20 to 69. Half had been diagnosed with invasive breast cancer and, for comparison purposes, half had not. The women were interviewed about their bone health their history of fractures, whether they'd been diagnosed with osteoporosis and their history of bisphosphonate use.

Breast cancer risk factors such as first-degree family history of the disease, age at first birth, postmenopausal hormone use and body m
'/>"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
2. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
3. Contrast-enhanced MRI could play a key role in differentiating between common types of arthritis
4. Migraine More Common in Women with MS
5. New therapeutic target for most common solid cancer in childhood?
6. US21, Inc. is Granted a Wholesale Distributor Permit from the Commonwealth of Virginia Board of Pharmacy
7. U.S. National Guard Connects Nationwide with Desktop Alert's Command and Control Mass Notification Systems and Common Alerting Protocol (CAP)
8. A common cholesterol drug fights cataracts, too
9. Adapting to clogged airways makes common pathogen resist powerful drugs
10. Metabolite common among cancers
11. Nutrition Management Services Company Announces Decision to Deregister its Class A Common Stock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... October 01, 2014 Insuranceragents.info has ... a good life insurance plan for vulnerable family members. ... vulnerable family members. Providers in the family should always ... cause financial hardships for the rest of the family. ... policies. Families can benefit more from temporary coverage or ...
(Date:10/1/2014)... October 01, 2014 Phoseon Technology, the ... continues to expand the business worldwide. This rapid growth ... additional capacity for manufacturing efforts. The company has experienced ... five years and expects this growth to continue in ... technology gains worldwide adoption. , “We are very ...
(Date:10/1/2014)... A new genetic finding from Duke Medicine suggests that ... depression might also be hard-wired to gain weight when ... disease. , An estimated 13 percent of people, all ... and knowing this could help them reduce heart disease ... and stress management. , "Genetic susceptibility, psychosocial stress and ...
(Date:10/1/2014)... Jersey City, NJ (PRWEB) October 01, 2014 ... sticking with their intentions to lose weight and their dieting ... in unhealthy, fatty foods. Including hormone diet treatments ... not only allows patients to see fast and effective weight ... diet and begin forming healthy habits to maintain their weight ...
(Date:10/1/2014)... 2014 On Sept. 9, Chapín Coffee ... the Martha Stewart American Made Awards (MSAMAs), an annual ... country in the fields of crafts, design, food and ... a finalist in the MSAMAs, which celebrates entrepreneurs and ... improving local communities and changing the way we shop, ...
Breaking Medicine News(10 mins):Health News:Life Insurance for Families - Clients Can Compare Affordable Rates Online! 2Health News:Phoseon Technology Continues to Drive Growth Worldwide 2Health News:Gene interacts with stress and leads to heart disease in some people 2Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 2Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 3Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 4Health News:Chicago Coffee Start-up Makes a Big Impact, Earns National Recognition 2
... experimental vaccine developed by researchers at Cedars-Sinai Medical Center,s ... aggressive brain tumors and improves length of survival in ... presented in a poster session at the 47th Annual ... Patients with newly diagnosed glioblastoma multiforme, the most ...
... biologists at Cold Spring Harbor Laboratory (CSHL) have obtained ... an allosteric inhibitor in a subtype of the NMDA ... The newly discovered binding site -- a ... it is a potential target for drugs that can ...
... By Maureen Salamon HealthDay Reporter ... research in Illinois reveals that medical specialists refuse ... conditions six times more often than privately insured ... mothers of children with seven common health conditions ...
... , WEDNESDAY, June 15 (HealthDay News) -- Medical ... look beyond survival and plan for the future. But for ... researchers say. In fact, researchers from Penn State found ... each year in medical care costs than people who have ...
... 15, 2011 A University of Houston (UH) chemist who ... published papers in two high-impact journals this month. ... colleagues have developed two different materials that are both equally ... June issues of Chemical Communications ( ChemComm ) ...
... the journal Nature , scientists discovered an entirely new ... are significant because they may ultimately help researchers alter the ... dystrophy and many forms of cancer. The genetic ... tell a cell how to make a specific protein. Central ...
Cached Medicine News:Health News:Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors 2Health News:Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors 3Health News:CSHL structural biologists reveal novel drug binding site in NMDA receptor subunit 2Health News:Specialists Often Turn Away Kids With Public Insurance: Report 2Health News:Specialists Often Turn Away Kids With Public Insurance: Report 3Health News:Cancer Survivors Face High Health Costs Over Long Term: Report 2Health News:UH chemist developing materials to detect, repel E. coli 2Health News:Changing genetic 'red light' to green holds promise for treating disease 2Health News:Changing genetic 'red light' to green holds promise for treating disease 3
(Date:10/1/2014)...   Cypher Genomics, Inc., the genome informatics ... Ravenel as chief technology officer. Ravenel has more ... and a proven track record of designing and architecting ... has been recognized as a top designer and architect ... industry-wide for delivering innovative products that operate at scale ...
(Date:10/1/2014)... 1, 2014   Royal Philips (NYSE: ... its eCareCoordinator and eCareCompanion telehealth applications have received ... Administration (FDA). A part of Philips Hospital to ... and eCareCompanion are focused on patient care within ... to be available through the cloud-based digital health ...
(Date:10/1/2014)... 1, 2014  CVS Health is thanking its 26,000 ... in changing the way health care is delivered to ... Company,s retail pharmacies, mail service pharmacies and specialty pharmacies ... company name to CVS Health to reflect our broader ... innovations needed to shape the future of health," said ...
Breaking Medicine Technology:Cypher Genomics Appoints J. Patrick Ravenel Chief Technology Officer 2Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 2Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 3Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 4CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 2CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 3
... Aug. 30 Brothers blow the numbers away. ... short years ago and have never looked back. ... (Logo:   http://photos.prnewswire.com/prnh/20100817/INC5000LOGO ) (Logo:  http://www.newscom.com/cgi-bin/prnh/20100817/INC5000LOGO) ... provider of low cost ultrasound systems in the ...
... FALLS, N.Y., Aug. 30 Laerdal Medical has ... training since the company launched its famous Resusci ... extensive experience to bear as it launches its ... (Photo: http://photos.prnewswire.com/prnh/20100830/NY56743 ) (Photo: ...
Cached Medicine Technology:National Ultrasound Makes the Inc 5000 List for Third Year in a Row 2Laerdal Introduces SimMan Essential 2Laerdal Introduces SimMan Essential 3
... sensitivity (threshold) testing provides clinically beneficial ... ophthalmic conditions. Dark adaptometry is useful ... retinal degenerations, senile miosis, high myopia, ... conditions, while whole-field scotopic sensitivity has ...
... The MFERG is available in conjunction with ... UTAS-E3000mf or EPIC-4000 or as a stand-alone ... visual electrodiagnostic test uses a software controlled ... to stimulate many areas of the retina ...
... Amplifier (UBA-4204) from LKC Technologies, ... amplification and complete electrical isolation ... problems of DC drifting, 50/60Hz ... make the amplifier ideal for ...
... to facilitate an arthrodesis, either by an ... cages allowing radicular compression by restoring the ... of the foramina, which in turn enhances ... major lumbar instabilities.,CC cages are made of ...
Medicine Products: