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Common medications can contribute to lower urinary tract symptoms in men
Date:10/11/2011

scribe an additional medication or suggest surgery. Clinically, the findings from this study suggest that an important step in evaluation of LUTS would be to review the medications the patient is already taking. When necessary, doctors should consider changing the medications which may be causing LUTS before adding new medications or invasive therapy," said Dr. Wuerstle.

The Kaiser Permanente study found:

  • antidepressants account for 4 % of LUTS
  • diuretics account for 3 % of LUTS
  • bronchodilators account for 2 % of LUTS
  • antihistamines account for 1% of LUTS

Medication use varied by race/ethnicity, with more Asian men using antihistamines (16%) and African Americans using proportionately more diuretics (31%). African Americans had a greater proportion of moderate to severe LUTS while Asian Americans had a greater prevalence of mild LUTS.

This study is part of Kaiser Permanente's ongoing research into health disparities in an effort to eliminate them. A Kaiser Permanente study last year in the Journal of General Internal Medicine found that people with diabetes who have limited health literacy are at higher risk for hypoglycemia. Another Kaiser Permanente study last year in the Journal of Community Health found that community intervention can help American Indian families change behavior related to early childhood weight gain, obesity and behavior change. More information on Kaiser Permanente's health disparities work can be found here: kp.org/healthdisparities

Medication use also increased with age, especially bronchodilators, anticholinergics, and diuretics. The strongest age-related increase was observed with diuretic use, from 8 percent in men aged 45 to 49 years to 23 percent in men aged 70 to 74 years. This drug in particular, can cause more frequent urination which could be mistaken for prostate disease.


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Contact: Sandra Hernandez-Millett
sandra.d.hernandez-millett@kp.org
626-405-5384
Kaiser Permanente
Source:Eurekalert

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