Navigation Links
Common bowel problem linked to chili pepper pain receptor
Date:6/10/2008

People with irritable bowel syndrome have a higher than usual number of chilli pepper pain receptors, according to a new study published tomorrow (Wednesday 11 June).

The research, published in the journal Gut, could lead to new therapies for the estimated one in five UK adults who have irritable bowel syndrome (IBS), a painful condition which is poorly understood. Symptoms of IBS include abdominal pain, bloating, and bowel problems such as constipation or diarrhoea.

The new research shows that people with IBS have higher than usual levels of nerve fibres expressing the pain receptor TRPV1, responsible for causing a burning sensation when people eat chilli peppers. The study's authors, from Imperial College London, hope that doctors could treat the pain that people with IBS experience by targeting and blocking this receptor.

People with severe pain from IBS are currently treated with opiates, which can have serious side-effects. Painkillers such as paracetamol and ibuprofen tend to offer little relief. New painkillers to target TRPV1 are currently being developed by pharmaceutical companies and the new findings suggest that such drugs could tackle some of the symptoms of IBS.

The researchers believe their findings may explain why some people's IBS symptoms worsen after eating spicy food. They also suggest that the presence of more nerve fibres expressing the TRPV1 pain receptors might mean that people with IBS are more susceptible to pain.

Professor Subrata Ghosh, one of the authors of the study from the Division of Medicine at Imperial College London, said: "IBS can seriously affect people's quality of life and our new study could explain some of its symptoms. At the moment patients don't have a lot of options for managing their condition and the treatments we can offer can give disappointing results. We hope that our findings will lead to better treatments to help people with IBS."

Professor
'/>"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Finding the source: Cells that initiate a common infant tumor identified
2. Inflammation, depression and antidepressant response: Common mechanisms
3. American Heart Association Survey Reveals Americans Lack Confidence in Lifesaving Skills for Common Cardiac Emergency
4. Common Genetic Variant Tied to Lung Cancer Risk
5. A common denominator of inflammations and fatty liver
6. Mayo Clinic researchers find common gene disorder doubles risk of lung cancer, even among nonsmokers
7. PA ABC Will Benefit Commonwealths Small Businesses, DCED Secretary Says
8. Incidental adrenal masses commonly seen on CT are usually benign; no follow-up needed
9. Smallpox Drug May Protect Against Common Cold
10. Womens Health Crisis: GI Problems Common in Women
11. Study finds 21st birthday binge drinking extremely common; can pose serious health hazards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Experience Mayan heritage and enjoy the spirit ... the luxury all-inclusive AAA Five Diamond Grand Velas Riviera ... ecological family tour where guests learn about local flora ... Tour at the Mayan archeological site of Coba. Guests ... the Yucatan and the only pyramid people are still ...
(Date:7/11/2014)... Steven Reinberg HealthDay Reporter ... hostility and depression may increase the risk for stroke, a ... to raise the risk of a stroke or a ... that stress apparently raised stroke or TIA risk by 59 ... TIA is a mini-stroke caused by a temporary blockage of ...
(Date:7/11/2014)... exercise as medicine, according to a QUT study ... essential to reducing the risk of death in ... Institute of Health and Biomedical Innovation, said that ... mental health, health professionals should be prescribing tailored ... and QUT,s Dr Charlotte Seib co-authored a paper ...
(Date:7/11/2014)... July 11, 2014 Bedros Keuilian is known ... title he’s earned by founding the fast-selling fitness franchise in ... their businesses. He works with successful boot camp owners on ... on the traits of the most successful boot camp owners ... important qualities. , “I’ve worked with and coached some of ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 Recently, iFitDress.com, ... special occasion outfits, has released its new collection of ... that, the company has announced that all these beautiful ... off. The deadline of the special offer is July ... its major officials pay close attention to customer satisfaction. ...
Breaking Medicine News(10 mins):Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 2Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 3Health News:Stress, Depression May Boost Stroke Risk, Study Finds 2Health News:Stress, Depression May Boost Stroke Risk, Study Finds 3Health News:Exercise is the best medicine: QUT study 2Health News:Fitness Boot Camp Marketing Expert Bedros Keuilian Shares the Top Three Traits of Successful Boot Camp Owners 2Health News:Fitness Boot Camp Marketing Expert Bedros Keuilian Shares the Top Three Traits of Successful Boot Camp Owners 3Health News:Worldwide Chic Ladies Can Buy Cheap Evening Dresses at iFitDress.com 2
... the cause of Women’s Heart Health by setting up 100 ... needs. These clinics will be spread across the country. ... chairman, Apollo Hospitals, spoke of Apollo’s plan to set up ... for Women (ACE), as it is called, will comprise of ...
... Eating a healthy die is very essential to maintain ... rich in nutrients such as fruits and vegetables along ... prevents chronic diseases like cancer, diabetes, obesity and hypertension. ... present in lean meats, eggs, beans, nuts and they ...
... attempt to spread awareness about AIDS/HIV, the Rotarians of ... organized a health awareness program// ('One step for awareness ... at barbers. ,The local barbers, under the ... special AIDS/HIV awareness session was conducted at Rotary Bhawan. ...
... well known fact that whole-grain foods keep triglycerides in their ... a study by Agricultural Research// Service scientists in California provides ... ,According to ARS chemist Nancy L. Keim, "Lipoproteins are the ... for energy, or to fatty tissue, where they're stored as ...
... after it was suggested that , one of the ... cabin air quality//.DVT is not caused by mere sitting in ... that cabin air quality may also play a key role. ... to throw up plausible risk factors risk factors. ,Low ...
... role in reducing the bad cholesterol. For example food like ... said that by combining these food substances one can get ... as they are at a higher risk of getting a ... cholesterol (LDL) as effectively as a commonly prescribed medication. ...
Cached Medicine News:Health News:A Complete Diet for Kids 2Health News:Fat fighters’: Whole-grain foods’: under the microsco 2Health News:Poor Quality of Cabin Air in the Plane Can Cause DVT, After A Long Flight 2Health News:Choose Foods That Keep Bad Cholesterol at Bay 2
(Date:1/15/2014)... 15, 2014 Sono-Tek Corporation (OTC BB: SOTK) today announced ... 2013, compared to sales of $2,202,000 for the prior year ... quarter has also shown growth over the preceding quarter,s sales, ... this fiscal year. Markets that experienced sales increases over the ...
(Date:1/15/2014)... RAPIDS, Mich. , Jan. 15, 2014 As health ... the flu virus, select Meijer pharmacies in Michigan ... strep throat to eligible patients, enabling Meijer pharmacists to administer ... strict protocol set by a physician participating in the study. ...
(Date:1/15/2014)... THOUSAND OAKS, Calif. , Jan. 15, 2014 ... and Amgen (NASDAQ: AMGN ) announced ... to jointly discover and validate new therapeutic targets ... (IBD), a chronic disorder that affects millions worldwide. ...
Breaking Medicine Technology:Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4
... makers of PharmASSIST® pharmacy automation solutions, today announced that ... OPTIx™, at Cardinal Health,s Retail Business Conference (RBC) in ... NACDS Pharmacy & Technology Conference in Boston, MA on ... imaging technology that enables pharmacies to automate the counting ...
... Better You from Blue, the Health ... Florida (BCBSF), is the first health insurer sponsored wellness ... the National Committee for Quality Assurance (NCQA) accreditation. NCQA ... accreditation that evaluates how well a health and wellness ...
Cached Medicine Technology:Innovation to Unveil New Pharmacy Automation Product at Key Pharmacy Industry Trade Shows 2Blue Cross and Blue Shield of Florida's Better You from Blue Program Awarded NCQA Accreditation 2
Adson bipolar forceps, 12 cm, straight....
Straight, blunt and pointed tips....
Angulated, blunt and pointed tips....
Blunt, 20 cm long....
Medicine Products: