Navigation Links
Common Skin Cancer a Chronic Condition, Study Says
Date:8/2/2012

By Barbara Bronson Gray
HealthDay Reporter

THURSDAY, Aug. 2 (HealthDay News) -- Here's yet another reason to go easy on the tanning this summer: A new study affirms that basal cell carcinoma, the most common form of skin cancer, should be viewed as a chronic disease.

That's because once most people have a single occurrence, they are at risk of getting another.

"Basal cell carcinoma has generally been viewed as something that comes up, is treated and cured," said Dr. Martin Weinstock, a study co-author and professor of dermatology at the Warren Alpert Medical School at Brown University in Providence, R.I. "For someone with an isolated lesion, that's a reasonable way of looking at it. But most people are constantly at risk of this and will be getting more."

The study confirmed what was commonly understood about the disease: a prior history of basal cell carcinoma is the greatest risk for another lesion. But the research found that eczema may also predict a recurrence among those at high risk for the disease. Those with a family history of eczema had a 1.54 times greater risk than those without.

Older age, sun sensitivity, intense sun exposure before age 30, and use of certain blood pressure-lowering medications (angiotensin-converting enzyme inhibitors or angiotensin receptor blockers) were also associated with increased risk.

Why would eczema, a chronic skin disorder that involves scaly and itchy rashes, be associated with basal cell carcinoma? Weinstock said it's unclear. "There may be some differences in these people's immune systems compared to people without eczema," he said, noting that other investigators need to confirm the findings.

Having other types of skin cancer or actinic keratoses (scaly or crusty growths caused by sun damage) did not appear to raise the chances for basal cell carcinoma.

The study was published online July 19 in the Journal of Investigative Dermatology and funded by the U.S. Department of Veterans Affairs. It involved more than 1,100 people, nearly all men, all veterans, with a median age of 72.

On average, each participant had more than three instances of basal cell cancer or squamous cell cancer (another type of skin cancer) before participating in the research. During the study period, 44 percent developed new basal cell cancers, and those with the most basal cell cancers in the five years before the study had the most recurrences.

Study participants with more than five prior basal cell cancers were nearly four times as likely to develop a new one as those with one or no prior skin cancers. And their risk was twice as high as those with three previous skin cancers, the study found.

Now the most common cancer in the United States, basal cell carcinoma begins in the outer layer of the skin, often as a small white or flesh-colored bump that grows slowly and sometimes bleeds. While these cancers rarely spread, they must be removed or treated, usually in a physician's office with local anesthetic.

Weinstock said researchers are eager to find a preventive medication to guard against the recurrence of basal cell carcinoma. Last year a team he led concluded that topical tretinoin did not prevent new basal cell cancers in high-risk patients. Now he is involved in a study looking at whether 5-Fluorouracil, a compound used to treat actinic keratoses, may prevent basal cell cancer when given intravenously.

Dr. Jean Tang, an assistant professor in the department of dermatology at Stanford University School of Medicine who is familiar with the study, said the most important thing for patients to know is that if you have had a basal cell carcinoma, you have a 44 percent chance of getting another.

"This study doesn't change any clinical guidelines or recommendations," she added. Current advice still stands: "Get an annual skin assessment by your dermatologist," she said.

More information

To learn more about skin cancer, visit the U.S. National Cancer Institute.

SOURCES: Martin Weinstock, M.D., Ph.D., professor, dermatology, Warren Alpert Medical School, Brown University, Providence, R.I.; Jean Tang, M.D., assistant professor, department of dermatology, Stanford University School of Medicine, Palo Alto, Calif.; July 19, 2012, Journal of Investigative Dermatolog, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Texting in College Classrooms Common, Distracting
2. Recovery from propofol anesthesia may be sped by use of common stimulant
3. Long-term neuropsychological impairment is common in acute lung injury survivors
4. Overuse Injuries Common Among Female College Athletes
5. Common Blood Pressure Drug Safe for Heart Failure: Study
6. Test links strains of common parasite to severe illness in US newborns
7. Common Plastics Chemical Might Boost Diabetes Risk
8. Off-Label Drug Use Appears Common
9. Global, common approach to pharmaceutical supply chain integrity the focus of workshop
10. Slow-growing babies more likely in normal-weight women; Less common in obese pregnancies
11. Common Blood Pressure Drugs May Not Cut Colon Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Common Skin Cancer a Chronic Condition, Study Says
(Date:2/22/2017)... ... February 22, 2017 , ... Doctors on Liens is continuing its ... Dr. Steven H. Rauchman, practicing at North Valley Eye Medical Group in Mission ... premise liability and other personal injury cases. These injuries have a major impact ...
(Date:2/22/2017)... ... February 22, 2017 , ... The ... today, as organizations, advocates, and individuals join together to increase recognition about the ... ultimately save lives. , “Today we mark a nationwide movement to raise awareness ...
(Date:2/22/2017)... ... February 22, 2017 , ... Bellus Medical, a leader in ... the delivery of Platelet Rich Plasma (PRP). PRP systems are used by physicians ... tissue synthesis and provide a faster and more efficient healing process. There are ...
(Date:2/22/2017)... ... February 22, 2017 , ... The SeniorCare Investor will ... Forecast —on Thursday, February 23, 2017, at 1:00 PM ET. A recording of the ... of the Interactive Webinar Series. , If you want to find out what really ...
(Date:2/22/2017)... ... February 22, 2017 , ... FPS is ... combat-related PTSD. , Established in 1977, our organization was at the forefront in ... returning to civilian life were evident and served as the catalyst for the ...
Breaking Medicine News(10 mins):
(Date:2/21/2017)... Patient Monitoring Equipment ... monitor physiological signs. These devices are either used as ... monitoring is one of the key factors for the ... market. Hence, vendors are developing technologically advanced products that ... send test results on time and provide better patient ...
(Date:2/21/2017)... Feb. 21, 2017 Micro Guide Catheters ... http://www.reportlinker.com/p04711314-summary/view-report.html Micro Guide Catheters ... hospitals, specialty clinics and ambulatory surgery centers etc. ... tip. The selection of micro guide catheter depends ... in human body. Micro guide catheters are available ...
(Date:2/21/2017)... IBM ) Research has today announced new research developments ... retina. The Melbourne based IBM researchers ... in retina images, which could in the future offer doctors ... who may be at risk of eye diseases – such ... world. The research began in 2015 and ...
Breaking Medicine Technology: