Navigation Links
Common Painkillers Might Boost Odds for 2nd Heart Attack
Date:9/11/2012

By Steven Reinberg
HealthDay Reporter

MONDAY, Sept. 10 (HealthDay News) -- People who've already suffered a heart attack may face higher odds of death or subsequent heart attack if they regularly take a common form of painkiller, Danish researchers report.

The painkillers are known as nonsteroidal anti-inflammatory drugs (NSAIDs), and include over-the-counter drugs such as ibuprofen (Advil, Motrin) and naproxen (Aleve), as well as prescription drugs such as Celebrex (celecoxib), the researchers noted.

"These results support previous findings that NSAIDs have no apparent safe treatment window among patients with a [prior] heart attack," said lead researcher Dr. Anne-Marie Schjerning Olsen from the department of cardiology at the University of Copenhagen. "Long-term caution with use of NSAIDs is advised in all patients after a heart attack," she said.

Olsen added that "it is important to get the message out to clinicians taking care of patients with cardiovascular disease that NSAIDs are harmful, even several years after a heart attack."

The report was published in the Sept. 10 issue of Circulation.

For the study, researchers collected data on almost 100,000 people who had experienced a heart attack between 1997 and 2009. They found that 44 percent of these patients had filled at least one prescription for an NSAID.

Compared to non-users, people who took the painkillers had a 59 percent higher risk of dying from any cause within a year after their heart attack, and a 63 percent higher risk within five years, the researchers found.

In addition, the risk of having another heart attack or dying from heart disease increased 30 percent within one year, and 41 percent after five years, the Danish team said.

These findings were the same for men and women regardless of age and income, the researchers found, and the study also accounted for factors such as other illnesses or medications.

Still, the data comes from what's known as an observational study, so it cannot prove that NSAIDs helped cause the deaths and heart attacks -- only that there was an association.

Nevertheless, the use of these drugs should be limited and the ability to buy them over-the-counter should be reconsidered, the researchers concluded.

"It has been shown in multiple prior studies that regular use of NSAIDs, including those that are available over the counter, is associated with increased risk of cardiovascular events," noted Dr. Gregg Fonarow, a spokesman for the American Heart Association and a professor of cardiology at the University of California, Los Angeles, who was not involved with the study.

"Even short-term use in patients after a heart attack or with heart failure has been associated with excess risk," he said.

Since 2007, American Heart Association guidelines have warned of the potential cardiovascular risk of NSAIDs in patients with established cardiovascular disease and after a heart attack and discouraged their use in these patients, Fonarow noted.

"This study highlights that substantial caution is necessary when considering NSAIDs in patients after a heart attack no matter how long ago the heart attack occurred," he said.

"Patients with a history [of heart attack] should consult with their physicians before taking NSAIDs, including those that are available over the counter," Fonarow added.

After a heart attack patients are usually prescribed aspirin, which is also an NSAID. However, "these findings do not apply to aspirin, which is a protective therapy after a heart attack," Fonarow stressed.

More information

For more information on heart attack, visit the American Heart Association.

SOURCES: Anne-Marie Schjerning Olsen, M.D., department of cardiology, University of Copenhagen, Denmark; Gregg Fonarow, M.D., spokesman, American Heart Association, and professor, cardiology, University of California, Los Angeles; Sept. 10, 2012, Circulation


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Texting in College Classrooms Common, Distracting
2. Recovery from propofol anesthesia may be sped by use of common stimulant
3. Long-term neuropsychological impairment is common in acute lung injury survivors
4. Overuse Injuries Common Among Female College Athletes
5. Common Blood Pressure Drug Safe for Heart Failure: Study
6. Test links strains of common parasite to severe illness in US newborns
7. Common Plastics Chemical Might Boost Diabetes Risk
8. Off-Label Drug Use Appears Common
9. Global, common approach to pharmaceutical supply chain integrity the focus of workshop
10. Slow-growing babies more likely in normal-weight women; Less common in obese pregnancies
11. Common Blood Pressure Drugs May Not Cut Colon Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Common Painkillers Might Boost Odds for 2nd Heart Attack
(Date:8/18/2017)... CARMEL, IN (PRWEB) , ... August 18, 2017 , ... ... 36th annual list, the most prestigious ranking of the nation's fastest-growing private companies. This ... in the exclusive Inc. 5000 ranking . This year’s ranking reflects ASH’s 76 ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Beyond Our Imaginations: The ... “Beyond Our Imaginations: The Infinite God” is the creation of published author, Mark Lawrence, ... country. , Lawrence shares, “The problem with becoming a greater man of God is ...
(Date:8/18/2017)... ... ... the Snake”: an entertaining and moral-based short story about an unkind snake learning a ... Jr., a husband, father and grandfather who served as a U.S. Marine, U.S. Army ... for children and teens. My goal is to teach kids to use good judgement ...
(Date:8/17/2017)... Delaware (PRWEB) , ... August 17, 2017 , ... When ... well actually, stretcher side nurse, she took with her a dream to make nursing ... of healthcare. Specifically, ensuring communication skills were integrated into healthcare provider education. ...
(Date:8/17/2017)... ... August 17, 2017 , ... Brookfield, ... for healthcare, hospitality and education, is celebrating its 30th year in business this ... begun at manufacturing companies Square D, Allis Chalmers and Johnson Controls. Following his ...
Breaking Medicine News(10 mins):
(Date:7/28/2017)... Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today announced financial results ... and updated its financial outlook for fiscal 2017. ... third quarter, Hill-Rom reported earnings of $0.09 per diluted ... prior-year period. These results reflect after-tax special items, including ... to the non-cash write-down of assets associated with the ...
(Date:7/27/2017)... Pa., July 27, 2017  West Pharmaceutical Services, Inc. ... results for the second-quarter 2017 and updated financial guidance ... Second-Quarter 2017 Highlights Reported net ... over the prior-year quarter. Net sales at constant currency ... reported-diluted EPS was $0.51, compared to $0.60 in the ...
(Date:7/26/2017)... , July 26, 2017 Sancilio Pharmaceuticals ... of our clinical trial evaluating Altemia TM , an ... (SCA) and Sickle Cell Disease (SCD). The SCOT Trial, ... the efficacy and safety of Altemia TM in ... conducted under US IND 125274. ...
Breaking Medicine Technology: