Navigation Links
Common Infections May Contribute to Strokes
Date:11/10/2009

But researchers not exactly sure how pathogens raise risk of brain attack

TUESDAY, Nov. 10 (HealthDay News) -- Exposure to several common pathogens may increase the risk of having a stroke, a new study shows.

Led by Dr. Mitchell Elkind, an associate professor of neurology at Columbia University Medical Center in New York City, the research team found that the pathogens Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus and herpes simplex virus 1 and 2 may be implicated in accelerating arterial disease, which in turn increases the risk of stroke.

The team's work appears in the Nov. 9 online edition of the Archives of Neurology, and will be published in the January 2010 print issue of the journal.

"These are infections that regularly pop up when we study heart disease," said Elkind. "They are very common in the population."

Scientists are not completely sure how the pathogens harm arterial function, but several theories offer suggestions. One possibility is that chronic infection leads to inflammation in the blood vessels, which can constrict blood flow. Another possibility, said Elkind, is that the pathogens disrupt the normal functioning of the arterial walls.

Strokes occur when there is a disruption in the blood supply to the brain, such as a blockage in an artery or other blood vessel. When this happens, brain cells begin to die, causing brain damage and even death. Common functions affected or lost during a stroke include speech, movement and memory.

Stroke is the third-leading cause of death in the United States, according to the National Stroke Association. Strokes have many causes, but it is widely known that certain risk factors increase the chances of having a stroke. These include high blood pressure, diabetes, high cholesterol, smoking and obesity.

In recent years, evidence has been uncovering the role of pathogens in cardiovascular disease, particularly the pathogens featured in Elkind's research. Scientists reported several years ago that untreated gum disease and other oral infections can spread and cause heart disease.

Elkind's study tracked 1,625 adults from a multi-ethnic community in Manhattan for 7.6 years. During that time, 67 patients suffered a first stroke. Even taking into account other risk factors, such as high blood pressure and diabetes, Elkind's team found that the majority of the patients tested positive for one or more of the suspected pathogens.

"Each individual infection was positively, though not significantly, associated with stroke risk after adjusting for other risk factors," the researchers wrote. "The infectious burden index was associated with an increased risk of all strokes after adjusting for demographics and risk factors."

It is too early to tell which pathogens contributed to the strokes, to what extent they contributed and how they contributed (through simple exposure or chronic infection), said Elkind. What's more, there may be other pathogens involved that were not included in the study, he added.

It is also too early to make any clinical recommendations. If scientists conclusively determine that pathogens are capable of causing strokes years after people come in contact with them, possible treatments may include wider and longer use of antibiotics, Elkind added.

Dr. Kishore Ranade, a neurologist affiliated with the Mount Kisco Medical Group in New York, said he was impressed with the findings. He suspects that pathogens work with other risk factors to cause strokes.

"Cumulative data have been suggesting that pathogens play a role in heart disease in general," said Ranade. "And what's bad for the heart is bad for the brain."

More information

The National Stroke Association has more on strokes, their causes and treatments.



SOURCES: Mitchell Elkind, M.D., Columbia University Medical Center, New York City; Kishore Ranade, M.D., Mount Kisco Medical Group, Mount Kisco, N.Y.; Nov. 9, 2009, Archives of Neurology, online


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Men leave: Separation and divorce far more common when the wife is the patient
2. The worlds most common operation
3. Common plants can eliminate indoor air pollutants
4. Smokers with common autoimmune disorder at higher risk for skin damage
5. Delays in Lung Cancer Care More Common in Public Hospitals
6. Epic Recording Brings Together Latin Artists Under a Common Cause
7. Caffeinated Cayenne Pepper Body Sprays Relieve Common Skin and Scalp Problems
8. Brisk Walk Can Help Leave Common Cold Behind
9. Common Knee Pain May Improve With Therapy
10. Inspired by Diabetes U.S. National Contest Winners Reveal Unique Challenges but Common Resolve in the Face of Diabetes
11. Common Antioxidant Might Slow Parkinsons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... , ... February 13, 2016 , ... The producers of ... of American businesses. , The increasingly modern world of instantaneous consumption proves very ... non-renewable energy sources such as oil and coal, which pollutes our air, water, and ...
(Date:2/13/2016)... ... February 13, 2016 , ... In the early or “honeymoon” stage ... to perfection, go out of their way to be romantic, and may exaggerate a ... look at any online dating profile. , A recent study from Queendom.com ...
(Date:2/12/2016)... ... , ... The law firm of Morrow, Morrow, Ryan & Bassett is offering ... scholarships is to encourage applicants to pursue a degree in their field of study ... , “We have available jobs in St. Landry and Evangeline Parishes that can ...
(Date:2/12/2016)... Falls Church, VA (PRWEB) , ... February 12, ... ... in Store?, Feb. 29, 2016 — 1:30 p.m. – 3:00 p.m. EST, ... burner issue in the life cycle of pharmaceutical products, garnering increased attention from ...
(Date:2/12/2016)... ... February 12, 2016 , ... T.E.N., a ... closed for the ISE Southeast Awards 2016. Finalists and winners of the ISE® ... Southeast Executive Forum and Awards Gala on March 15, 2016 at the Westin ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016 The primary ... and future adoption patterns on the usage of liquid ... the following: - Timeframe of liquid biopsy ... ctDNA, cfDNA and Evs—by organization type - Sample inflow ... types: blood, saliva, stool, serum, and so on. - ...
(Date:2/11/2016)... 11, 2016  Walgreens has committed to provide drug ... Washington, D.C. as part of a ... commended by shareholder advocacy organization As You Sow. ... "Many people hold on to unneeded drugs because they lack ... consequences." --> Conrad MacKerron , Senior Vice ...
(Date:2/11/2016)... Feb. 11, 2016  MiMedx Group, Inc. (NASDAQ: ... amniotic membrane and other birth tissues, human skin and ... and market advanced products and therapies, announced today that ... Global Healthcare Conference in New York ... Michael J. Senken , Chief Financial Officer and ...
Breaking Medicine Technology: