Navigation Links
Common Diabetes Drug Linked to Vitamin B-12 Deficiency
Date:5/21/2010

Type 2 patients taking metformin should get levels tested regularly, study suggests

FRIDAY, May 21 (HealthDay News) -- Diabetics who take the drug metformin over the long term should get their vitamin B-12 levels checked regularly to see if they are developing a vitamin deficiency, a new report suggests.

Metformin, also known by several brand names including Glucophage, is a common treatment for people with type 2 diabetes, but it can cause vitamin B-12 deficiency, according to the report published online May 21 in the journal BMJ.

Failing to check patients' vitamin levels may lead doctors to improperly diagnose the symptoms of B-12 deficiency, which include fatigue, mental changes, anemia and neuropathy. Doctors may mistakenly think these symptoms are caused by diabetes or aging, the study authors noted.

Researchers in the Netherlands led by Coen Stehouwer studied the effects of metformin treatment on 390 patients with type 2 diabetes. They prescribed either the drug (196 patients) or a placebo (194 patients) to be taken three times a day for more than four years.

Patients who took the drug had a 19 percent reduction in their vitamin B-12 levels compared to the other participants, who had little change. The reduction in B-12 levels continued and became more apparent over time in those taking metformin, the investigators found.

Meanwhile, the number of patients taking metformin who developed vitamin B-12 deficiency grew from three to 19, the authors reported.

"Our study shows that it is reasonable to assume harm will eventually occur in some patients with metformin-induced low vitamin B-12 levels," Stehouwer's team concluded. "Our data provide a strong case for routine assessment of vitamin B-12 levels during long-term treatment with metformin."

More information

The U.S. National Library of Medicine has more about metformin.



-- Randy Dotinga



SOURCE: BMJ, news release, May 21, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Happy Feet are Healthy Feet: Common Sense Tips on Taking Care of Your Feet to Survive the Holiday Season
2. Cracking the code on common wrist injury
3. Murtha Gallbladder Removal Complications Underscore Risk of Common Surgery
4. Sinovac Announces Closing of Common Share Offering
5. New model of skin cancer provides insights on second-most common type of cancer
6. Parkinsons More Common in Northeast, Midwest
7. Skipping Insulin May Not Be Uncommon
8. Common antidepressant drugs linked to lactation difficulties in moms
9. Complications common, often linked to trauma in children receiving cochlear implants
10. Deadly Choking Game Still Common Among Kids
11. New White Paper Details Six Common Bad Assumptions About Hearing Protection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... , ... June 27, 2016 , ... TopConsumerReviews.com recently awarded ... Eyeglasses . , Millions of individuals in the United States and Canada wear ... a way to both correct vision and make a fashion statement. Even celebrities use ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media ... give their videos a whole new perspective by using the title layers in ... Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: DHRM ) ... medical devices and wearable sleep respiratory products in ... with Hongyuan Supply Chain Management Co., Ltd. (hereinafter referred ... to develop Dehaier,s new Internet medical technology business. ... Hongyuan Supply Chain,s sales platform to reach Dehaier,s dealers ...
Breaking Medicine Technology: