Navigation Links
Common Diabetes Drug Linked to Vitamin B-12 Deficiency
Date:5/21/2010

Type 2 patients taking metformin should get levels tested regularly, study suggests

FRIDAY, May 21 (HealthDay News) -- Diabetics who take the drug metformin over the long term should get their vitamin B-12 levels checked regularly to see if they are developing a vitamin deficiency, a new report suggests.

Metformin, also known by several brand names including Glucophage, is a common treatment for people with type 2 diabetes, but it can cause vitamin B-12 deficiency, according to the report published online May 21 in the journal BMJ.

Failing to check patients' vitamin levels may lead doctors to improperly diagnose the symptoms of B-12 deficiency, which include fatigue, mental changes, anemia and neuropathy. Doctors may mistakenly think these symptoms are caused by diabetes or aging, the study authors noted.

Researchers in the Netherlands led by Coen Stehouwer studied the effects of metformin treatment on 390 patients with type 2 diabetes. They prescribed either the drug (196 patients) or a placebo (194 patients) to be taken three times a day for more than four years.

Patients who took the drug had a 19 percent reduction in their vitamin B-12 levels compared to the other participants, who had little change. The reduction in B-12 levels continued and became more apparent over time in those taking metformin, the investigators found.

Meanwhile, the number of patients taking metformin who developed vitamin B-12 deficiency grew from three to 19, the authors reported.

"Our study shows that it is reasonable to assume harm will eventually occur in some patients with metformin-induced low vitamin B-12 levels," Stehouwer's team concluded. "Our data provide a strong case for routine assessment of vitamin B-12 levels during long-term treatment with metformin."

More information

The U.S. National Library of Medicine has more about metformin.



-- Randy Dotinga



SOURCE: BMJ, news release, May 21, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Happy Feet are Healthy Feet: Common Sense Tips on Taking Care of Your Feet to Survive the Holiday Season
2. Cracking the code on common wrist injury
3. Murtha Gallbladder Removal Complications Underscore Risk of Common Surgery
4. Sinovac Announces Closing of Common Share Offering
5. New model of skin cancer provides insights on second-most common type of cancer
6. Parkinsons More Common in Northeast, Midwest
7. Skipping Insulin May Not Be Uncommon
8. Common antidepressant drugs linked to lactation difficulties in moms
9. Complications common, often linked to trauma in children receiving cochlear implants
10. Deadly Choking Game Still Common Among Kids
11. New White Paper Details Six Common Bad Assumptions About Hearing Protection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... While it’s often important to take certain medications during the night, finding ... identified a solution. , She developed a prototype for MOTION LIGHT-UP PILL BOX to ... the need to turn on a light when taking medication during the night, allowing ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which ... evacuation of the facility as part of a disaster drill on October 3rd. , ... and Shelton City Emergency Manager, as well as the Connecticut Long Term Care ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, ... formed by Walgreens and pharmacy benefit manager Prime Therapeutics ... new brand, which included the unveiling of new signage ... , as well as at a few other company-owned ... new brand to patients, some of whom will begin ...
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: