Navigation Links
Common Diabetes Drug Linked to Vitamin B-12 Deficiency
Date:5/21/2010

Type 2 patients taking metformin should get levels tested regularly, study suggests

FRIDAY, May 21 (HealthDay News) -- Diabetics who take the drug metformin over the long term should get their vitamin B-12 levels checked regularly to see if they are developing a vitamin deficiency, a new report suggests.

Metformin, also known by several brand names including Glucophage, is a common treatment for people with type 2 diabetes, but it can cause vitamin B-12 deficiency, according to the report published online May 21 in the journal BMJ.

Failing to check patients' vitamin levels may lead doctors to improperly diagnose the symptoms of B-12 deficiency, which include fatigue, mental changes, anemia and neuropathy. Doctors may mistakenly think these symptoms are caused by diabetes or aging, the study authors noted.

Researchers in the Netherlands led by Coen Stehouwer studied the effects of metformin treatment on 390 patients with type 2 diabetes. They prescribed either the drug (196 patients) or a placebo (194 patients) to be taken three times a day for more than four years.

Patients who took the drug had a 19 percent reduction in their vitamin B-12 levels compared to the other participants, who had little change. The reduction in B-12 levels continued and became more apparent over time in those taking metformin, the investigators found.

Meanwhile, the number of patients taking metformin who developed vitamin B-12 deficiency grew from three to 19, the authors reported.

"Our study shows that it is reasonable to assume harm will eventually occur in some patients with metformin-induced low vitamin B-12 levels," Stehouwer's team concluded. "Our data provide a strong case for routine assessment of vitamin B-12 levels during long-term treatment with metformin."

More information

The U.S. National Library of Medicine has more about metformin.



-- Randy Dotinga



SOURCE: BMJ, news release, May 21, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Happy Feet are Healthy Feet: Common Sense Tips on Taking Care of Your Feet to Survive the Holiday Season
2. Cracking the code on common wrist injury
3. Murtha Gallbladder Removal Complications Underscore Risk of Common Surgery
4. Sinovac Announces Closing of Common Share Offering
5. New model of skin cancer provides insights on second-most common type of cancer
6. Parkinsons More Common in Northeast, Midwest
7. Skipping Insulin May Not Be Uncommon
8. Common antidepressant drugs linked to lactation difficulties in moms
9. Complications common, often linked to trauma in children receiving cochlear implants
10. Deadly Choking Game Still Common Among Kids
11. New White Paper Details Six Common Bad Assumptions About Hearing Protection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... Ensuring ... two new videos highlight the importance of correctly using a meat thermometer. The ... has done extensive research on consumer food safety habits. Dr. Bruhn explains the ...
(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and South Asia Leaders Selected ... from government, business and civil society in 11 countries across the Middle East and ... in a transformative exchange of knowledge and ideas with the leading minds in their ...
(Date:6/23/2017)... ... 2017 , ... PureLife Dental is pleased to announce that California Dental Association ... part of the amalgam separator endorsement, all CDA members may purchase an ECO II ... retail value. This partnership between PureLife and CDA is especially timely as it coincides ...
(Date:6/23/2017)... ... , ... American Farmer, will feature Chr. Hansen, Inc (CHR Hansen) in an ... 2017. American Farmer airs Tuesdays at 8:30aET on RFD-TV. Check your local listings for ... Denmark in 1874 after a groundbreaking discovery of how to industrialize enzymes. Rooted in ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... and related services to families and business owners in and around Lackawanna County, ... benefit senior citizens in the area. , Meals on Wheels of NEPA provides ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... Texas , June 8, 2017 /PRNewswire/ ... a leading developer and manufacturer of diagnostic ... announced today that Cressey & Company LP ... firm, has completed a growth-focused investment in ... a majority ownership position from selling shareholder, ...
(Date:6/5/2017)... CINCINNATI , June 5, 2017 The ... a brand of Diplomat Pharmacy, Inc. (NYSE: DPLO), has been ... Cincinnati Enquirer . Results are based on ... specializing in organizational health and workplace improvement. The survey measures ... ...
(Date:6/1/2017)... June 1, 2017 Nutriceutical Holdings (NH), parent ... Solutions (VRS), and KD Pharma Group have decided to ... by KD Pharma Group. KD Pharma Group will become ... to acquire the entire company. "We believe ... are committed to growing the NH companies by providing ...
Breaking Medicine Technology: