Navigation Links
Common Blood Pressure Drugs May Not Cut Colon Cancer Risk
Date:5/14/2012

MONDAY, May 14 (HealthDay News) -- Widely used blood pressure medications called beta blockers do not cut a person's odds of developing colon cancer, a new study contends.

Beta blockers, which include drugs such as alprenolol, carvedilol, propranolol and atenolol, are commonly prescribed to older adults for high blood pressure and heart conditions.

Prior research has also linked use of the drugs to a decreased risk of cancer. This theory is based on animal and laboratory studies that found that the stress hormone norepinephrine can promote the growth and spread of cancer cells. Beta blockers inhibit this hormone's action.

"One of the holy grails in the war on cancer is preventing angiogenesis, which is the growth of new blood vessels to feed tumor cells," explained Dr. David Robbins, associate chief of the Center for Advanced Therapeutic Endoscopy at Lenox Hill Hospital in New York City.

"Some investigators have speculated that an indirect benefit of certain blood pressure medicines may be to help curb the growth of new blood vessels in breast and perhaps colon cancer," said Robbins, who was not involved in the new study.

In this study, published online May 14 in the journal Cancer, a team led by Michael Hoffmeister, of the German Cancer Research Center in Heidelberg, compared the beta blocker use of more than 1,700 colon cancer patients to that of about the same number of cancer-free people.

After accounting for weight, smoking status and other patient factors, the researchers found no link between beta blocker use and colon cancer risk.

The finding held true even after the researchers broke down their analyses by duration of beta blocker use, specific types of beta blockers, and sites within the colon or rectum where colorectal cancer developed in patients.

The authors conclude that their findings do not support the theory that using beta blockers cuts colon cancer risk.

That didn't surprise Robbins. "The few studies on this matter have been contradictory and it's unlikely that we'll ever see this sort of protective effect, since cancer is an incredibly complex disease driven by a myriad of unique biologic pathways," he said.

Another expert added that even though beta blockers might not help prevent colon tumors, people have other means of doing so.

"Men and women at average risk should start getting screened at age 50," said Dr. Mark Pochapin, director of the division of gastroenterology at NYU Langone Medical Center in New York City. "Those with certain risk factors, such as a family history of colorectal polyps or cancer, should talk to their doctors about screening at a younger age."

Pochapin also added that "lifestyle modifications -- such as quitting smoking, avoiding excess intake of red or processed meats, ensuring adequate vitamin D intake, and maintaining a healthy body weight and regular exercise -- can be very beneficial in reducing one's risk for colorectal cancer."

More information

The U.S. National Cancer Institute has more about colorectal cancer risk factors and prevention.

-- Robert Preidt

SOURCES: David H. Robbins, M.D., associate chief, Center for Advanced Therapeutic Endoscopy, Lenox Hill Hospital, New York City; Mark B. Pochapin, M.D., director, division of gastroenterology, NYU Langone Medical Center, New York City; Cancer, news release, May 14, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Adapting to clogged airways makes common pathogen resist powerful drugs
2. A common cholesterol drug fights cataracts, too
3. U.S. National Guard Connects Nationwide with Desktop Alert's Command and Control Mass Notification Systems and Common Alerting Protocol (CAP)
4. US21, Inc. is Granted a Wholesale Distributor Permit from the Commonwealth of Virginia Board of Pharmacy
5. New therapeutic target for most common solid cancer in childhood?
6. Migraine More Common in Women with MS
7. Contrast-enhanced MRI could play a key role in differentiating between common types of arthritis
8. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
9. Six "Common Sense" Points Not Included In The Health Care Discussion? Should They Be?
10. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
11. Commonwealth Leverage Group and Helium Interactive Form HIE Go-To-Market Partnership
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Common Blood Pressure Drugs May Not Cut Colon Cancer Risk
(Date:6/26/2016)... , ... June 26, 2016 , ... On June 10-11, ... of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, ... the city’s history as home to some of the world’s leading providers of cereal ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. ... his M.D from the David Geffen School of Medicine at UCLA. He trained in ... to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
Breaking Medicine Technology: