Navigation Links
Combo Therapy Shows Promise in Treating Brain Tumors
Date:1/18/2008

Radiation seeds, chemo wafers slowed disease, boosted survival

FRIDAY, Jan. 18 (HealthDay News) -- Implantation of radioactive seeds and chemotherapy wafers following surgery shows promise in treating malignant brain tumors, a new study finds.

The early-phase clinical trial, led by researchers at The Neuroscience Institute at the University of Cincinnati and University Hospital, included 34 patients who had the combination therapy after surgery to remove recurrent glioblastoma multiforme (GBM).

The study, designed to assess the safety and effectiveness of simultaneous use of radioactive seeds and chemotherapy wafers, found that median patient survival was 69 weeks. Almost 25 percent (eight) of the patients survived two years. Patients with recurrent GBM who receive conventional treatment (chemotherapy) have a median survival of about 26 weeks.

About 25 percent of patients developed brain tissue death, which was treated with surgery or hyperbaric oxygen and did not affect survival. That rate of brain tissue death appeared to be higher than what's seen in patients treated with either seeds or wafers alone.

"Treatment of recurrent GBM presents a major challenge to neurosurgeons and neuro-oncologists," study author Dr. Ronald Warnick, a professor of neurosurgery, said in a prepared statement.

"Glioblastoma is an aggressive, highly malignant tumor with unclear boundaries. Because of its diffuse nature, surgeons are unable to remove it completely, and it regrows in the majority of patients. Our aim is to find a way to keep the infiltrating glioblastoma cells from growing into adjacent, health tissue," he said.

The radiation seeds, each about the size of a grain of rice, deliver radiation to the targeted area for six months. The chemotherapy wafers, which are about the size of a nickel, are placed along the surface of the brain.

Compared with the use of either one alone, the combination of the seeds and wafers appeared to further delay disease progression and increase length of patient survival, Warnick said.

However, he noted that the effectiveness of the combination therapy is not definitive, because this study did not include a control group.

The study was published in the February issue of the Journal of Neurosurgery.

More information

The U.S. National Cancer Institute has more about brain tumors.



-- Robert Preidt



SOURCE: University of Cincinnati, news release, Jan. 18, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Combo Treatment Best for Elderly Lymphoma Patients
2. Combo Therapy Cuts Prostate Cancer Death Rates
3. Drug Combo Halves Death Risk for Severe COPD Patients
4. Aspirin, Hormone Therapy Combo Can Shorten Lives of Prostate Cancer Patients
5. New Combo Treatment Extends Kidney Cancer Survival
6. Drug Combo With Antibiotic May Slow MS Progression
7. Combo PET/CT Scan Helps Spot Breast Cancers Spread
8. Drug Combos Effective Against Rheumatoid Arthritis
9. Drug Combo Boosts Multiple Myeloma Survival
10. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
11. Two-Drug Combo Fights Brain Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Combo Therapy Shows Promise in Treating Brain Tumors
(Date:5/31/2016)... ... May 31, 2016 , ... In his latest video, ... traits in humans. Using presidential candidate Donald Trump as an example, Kalsi describes ... “AstroNumerology is not about adding numbers up,” says Kalsi. “It is about looking ...
(Date:5/31/2016)... , ... May 31, 2016 , ... Phynd Technologies, Inc. ... GA; Houston Methodist – Houston, TX and Shore Medical Center – Somers Point, NJ. ... three different, leading EHR solutions, demonstrating the breadth of Phynd’s solution and its interoperability. ...
(Date:5/31/2016)... ... May 31, 2016 , ... Dr. Charles A. Ditta ... of New Jersey in the class of 1986, where he graduated in the top ... his current location in Livingston since 1989. He has been a member in good ...
(Date:5/31/2016)... ... ... Super Powder, a supplement produced by Prox Formulas for providing protein ... to transform the nutritional supplement industry by providing a safe, natural approach to enhanced ... (BCAA), alkaline minerals, wheat grass, digestive enzymes, Omega 3’s, Vit D3, Vit A, B1, ...
(Date:5/30/2016)... ... May 30, 2016 , ... ... Shaolin warrior 8-day-8 and 8-night special intensive summer training camp starts on June ... summer camp offers families and children a fun and unique experience with an ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... 2016 According to the 2016 ... driving ambulatory blood pressure monitoring system market growth. With ... ability to respond to different pressure rates, leading to ... to various cardiovascular disorders such as heart failure, stroke, ... are growing in prevalence each year. WHO estimates that ...
(Date:5/26/2016)... May 26, 2016 According to a ... Management Market - U.S. Industry Analysis, Size, Share, Growth, Trends, ... in the U.S. was valued at US$ 5.89 Bn in ... 3.4% from 2015 to 2023 to reach US$ 7.99 Bn ... current and emerging needle free drug delivery devices and the ...
(Date:5/25/2016)... May 25,2016 FDA 510(k) ... Cellvizio platform for urological and surgical applications ... inventor of Cellvizio®, the multidisciplinary confocal laser endomicroscopy ... in the US with the 12 th ... Administration (FDA). This new FDA clearance covers Confocal ...
Breaking Medicine Technology: