Navigation Links
Combo Therapies to Lower Cholesterol Don't Work
Date:9/2/2009

Review shows evidence doesn't support using other treatments with statins

WEDNESDAY, Sept. 2 (HealthDay News) -- Despite their popularity, so-called "combination therapies" may not be the most effective treatment for high cholesterol, Canadian researchers report.

In their review, the scientists analyzed data from 102 studies that tested combination therapies involving ezetimibe, niacin, bile acid sequestrants and omega-3 fatty acids. They concluded that there is little evidence to support the widespread use of combination therapies to lower cholesterol.

The results of this comprehensive review of clinical studies are important, as lowering cholesterol has been shown to decrease the risk of heart attack and stroke, and more than 35 million Canadians and Americans are prescribed cholesterol-lowering drugs each year, according to a news release from the Ottawa Hospital Research Institute.

In the new study, stroke specialist Dr. Mukul Sharma and colleagues from the Ottawa Hospital Research Institute and the University of Ottawa looked for evidence that supported the use of combination therapies vs. high-dose statin therapy.

Although statins are the most commonly used class of cholesterol-lowering drugs, some people don't respond to the standard dose. For these people, statins are increasingly being prescribed at higher doses or in combination with other types of drugs, according to the report published online Sept. 1 in the Annals of Internal Medicine.

"Our review shows that so far, there is not enough evidence to support the widespread use of combination therapies over high-dose statin therapy," Sharma said in the news release. "For most patients who don't respond to a low dose of statin, it would make sense to try a higher dose of statin before trying a combination therapy. If the high-dose statin does not work or is not well-tolerated, or if there are other special circumstances, a combination therapy may be a good option, but until more research is done, this is not recommended for most patients."

More information

Learn more about high blood cholesterol from the U.S. National Heart, Lung, and Blood Institute.



-- Dennis Thompson



SOURCE: Ottawa Hospital Research Institute, news release, Aug. 31, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Radiation and drug combo helps boost efficacy of lung cancer treatment
2. Aerobic, Weight Training Combo Best Against Diabetes
3. New antibiotic drug combo to speed up treatment of tuberculosis
4. Drug Combo Helps Fight Marfan Syndrome
5. Drug Combo Blocks Pain Without Impairing Movement
6. Two-Drug Combo Fights Brain Tumors
7. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
8. Drug Combo Boosts Multiple Myeloma Survival
9. Drug Combos Effective Against Rheumatoid Arthritis
10. Combo PET/CT Scan Helps Spot Breast Cancers Spread
11. Drug Combo With Antibiotic May Slow MS Progression
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Combo Therapies to Lower Cholesterol Don't Work
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & Associates ... special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to date ... elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded by ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association ... Featuring a collection of specialty vendors and unique items from across the nation, this ... health and wellness services offered by the VNA. The boutique will be open ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 2017  EpiVax, Inc., a leader in the ... today announced the launch of EpiVax Oncology Inc., ... therapeutic cancer vaccines. EpiVax has provided $500,000 in ... enabling technologies to the new precision immunotherapy venture. ... Oncology as Chief Executive Officer. Gad brings over ...
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
(Date:9/13/2017)... Sept. 13, 2017   OrthoAtlanta has been named ... Football Host Committee (AFHC) for the 2018 College Football Playoff ... 2018, at Mercedes-Benz Stadium in Atlanta, Georgia ... AFHC "I,m In" campaign, participating in many activities leading up ... ...
Breaking Medicine Technology: