Navigation Links
Combined imaging technologies may better identify cancerous breast lesions
Date:11/9/2010

OAK BROOK, Ill. By combining optical and x-ray imaging, radiologists may be better able to distinguish cancer from benign lesions in the breast, according to a new study published in the online edition and January issue of Radiology.

Researchers at Martinos Center for Biomedical Imaging at Massachusetts General Hospital in Boston helped develop a combined optical/x-ray imaging system capable of obtaining both structural and functional information of the breast.

The two technologies used were digital breast tomosynthesis (DBT), a three-dimensional application of digital mammography, and diffuse optical tomography (DOT), which measures levels of hemoglobin concentration, oxygen saturation and other cellular characteristics, based on how light from a near-infrared laser is absorbed and scattered within tissue.

"By co-registering optical and x-ray data, radiologists are able to map suspicious findings and analyze the functional characteristics of those areas," said lead researcher Qianqian Fang, Ph.D., a radiology instructor at Harvard Medical School.

In the study, combined DBT and DOT was performed on 189 breasts from 125 women with an average age of 56 years. To perform the procedure, an optical source and detector probes were attached to a DBT unit and, with the breast compressed, optical data was acquired. The optical probes were then removed without altering the breast compression and a DBT scan was performed.

"We are very excited about adding optical imaging to DBT, because it is low-cost, safe, noninvasive and fast," Dr. Fang said.

Of the 189 imaging studies, 138 were negative, and 51 showed evidence of lesions. As determined by breast biopsy, 26 lesions of the 51 lesions were malignant, and 25 were benign.

In the 26 malignant tumors, total hemoglobin concentration (HbT) was significantly greater than in the normal glandular tissue of the same breast. Solid benign lesions and cysts had significantly lower HbT contrast compared to the malignant lesions.

"By providing additional differentiation of malignant and benign lesions, combined optical and x-ray imaging could potentially reduce unnecessary biopsies," Dr. Fang said.

In the study, oxygen saturation levels were significantly lower in cysts compared to those in malignant and solid benign lesions and glandular breast tissue.

"Although cysts are easy to diagnose using ultrasound, distinguishing cysts from malignant or benign lesions during a mammogram would save women the anxiety and costs associated with a second procedure," Dr. Fang said. "We are hopeful that this combined system may help improve the efficiency and diagnostic accuracy of breast screening."


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Combined mammography and breast MRI useful for some high-risk women
2. Combined drug therapy to treat TB and HIV significantly improves survival
3. ACCORD: Intensive BP, combined lipid therapies do not help adults with diabetes
4. Promega Maxwell 16 IVD System CE Marked to the European Union IVD Directive Delivers Combined Solution for Infectious Disease
5. Singapore Performs Asia's First Combined Heart and Liver Transplant
6. New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers
7. Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
8. Combined BRAF-targeted and immunotherapy shows promise for melanoma treatment
9. Neuroimaging study may pave way for effective Alzheimers treatments
10. SNMs Conjoint Mid-Winter Meetings continue to advance molecular imaging
11. Medical Imaging Northwest Completes Phase I of Its Healthcare IT Integration to Maintain Patient Care Improvements
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 09, 2016 , ... Ross A. Clevens, MD, ... to welcome a new addition to their growing practice. Beginning this month, Teresa ... nurse practitioner performing cosmetic procedures including injectables, fillers and laser treatments. ...
(Date:2/9/2016)... ... February 09, 2016 , ... Steven Douglas Associates is a ... Florida Event, an upscale fundraiser held in South Florida. The Inaugural What’s Your Taste ... This year the event will be held in a new, more causal format at ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... production of its newest mobility device, the StandUp Walker. Made entirely in the ... in the last 50 years. , StandUp Walker’s novel patent-pending design offers 2-in-1 ...
(Date:2/9/2016)... Springs, FL (PRWEB) , ... February 09, 2016 ... ... leading innovative specialty pharmacies, announces today the continuation of the ‘Pay It Forward’ ... for each prescription referral received at our specialty pharmacy. , “Since our ...
(Date:2/9/2016)... ... February 09, 2016 , ... The Bon-Ton Stores, Inc. (NASDAQ: ... stores, announced it has raised $176,000 to benefit the Breast Cancer Research Foundation, ... at the University of Iowa, The Lynn Sage Cancer Research Foundation, and Masonic ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... , Feb. 9, 2016 On ... Administration (FDA) met with its Arthritis Advisory ... biosimilar of Johnson & Johnson,s Remicade and ... approved in the U.S. The Biologics Prescribers ... groups - Alliance for Patient Access, American ...
(Date:2/9/2016)... Calif. , Feb. 9, 2016 /PRNewswire/ - Nevro ... company that is providing innovative evidence-based solutions for the ... release financial results for the fourth quarter and full ... 29, 2016. Company management will host a conference call ... Time) on Monday, February 29, 2016. www.nevro.com ...
(Date:2/9/2016)... 9, 2016  Sangamo BioSciences, Inc. (NASDAQ: ... today reported its fourth quarter and full year ... vivo therapeutic genome editing," said Edward Lanphier, ... finger nuclease (ZFN) technology leads the therapeutic genome ... competencies necessary to move our ground-breaking genome editing ...
Breaking Medicine Technology: