Navigation Links
Combined arterial imaging technology reveals both structural and metabolic details
Date:11/6/2011

ration with colleagues at the Technical University of Munich, and uses special imaging agents to detect cells and molecules involved in vascular processes like clotting and inflammation. Recognizing the potential advantage of combining both technologies, the Wellman researchers worked with the MGH-CVRC team, led by Farouc Jaffer, MD, PhD, of the MGH Heart Center to develop an integrated OFDI-NIRF imaging system incorporated in the same intravascular probe used for OFDI alone.

The team first confirmed that the system could provide detailed structural images of a stent implanted in a cadaveric human coronary artery and could accurately identify the presence of fibrin on the stent. In a series of experiments in living rabbits, the OFDI-NIRF system was able to detect fibrin on implanted stents including areas where it was not detected by OFDI alone and to identify the presence of both atherosclerotic plaques and enzymatic activity associated with inflammation and plaque rupture. The enzyme signal detected by NIRF was not uniform throughout the imaged plaques, indicating biological differences that could be relevant to prognosis and treatment planning.

"At present we are not able to predict which patients may develop stent thrombosis, but integrated OFDI-NIRF can assess many key factors linked to the risk of clot formation," says Jaffer, co-senior author of the Nature Medicine report. "If OFDI-NIRF is validated in clinical studies, patients at risk for stent thrombosis could undergo a 'stent checkup' to determine how well the stent is healing. Patients with unhealed stents could be advised to take or continue taking specific anti-clotting medications. Patients with well-healed stents, on the other hand, could potentially discontinue anti-clotting medications, which can cause excess bleeding." Clinical adoption of the integrated technology will require FDA approval of the molecular contrast agents used in NIRF.


'/>"/>
Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Combined mammography and breast MRI useful for some high-risk women
2. Combined drug therapy to treat TB and HIV significantly improves survival
3. ACCORD: Intensive BP, combined lipid therapies do not help adults with diabetes
4. Promega Maxwell 16 IVD System CE Marked to the European Union IVD Directive Delivers Combined Solution for Infectious Disease
5. Singapore Performs Asia's First Combined Heart and Liver Transplant
6. New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers
7. Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
8. Combined BRAF-targeted and immunotherapy shows promise for melanoma treatment
9. Combined imaging technologies may better identify cancerous breast lesions
10. Ultrasound combined with pre-operative MRI is cost effective in evaluating rotator cuff tears
11. Novel combined therapy extends life, diminishes pain in brain cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Combined arterial imaging technology reveals both structural and metabolic details
(Date:7/30/2015)... ... ... connection between a healthy head of hair and a feeling of confidence is a powerful ... can have a devastating impact on the daily life of a person. From increased ... of hair loss are not to be taken lightly. , The skilled staff at Parsa ...
(Date:7/30/2015)... New York, NY (PRWEB) , ... July 30, ... ... with Setria®Glutathione and Sustamine® L-Alanyl-L-Glutamine for people on the go. With no water ... Zaca Recovery Chewable as a simple way to get the natural ingredients that ...
(Date:7/30/2015)... ... July 30, 2015 , ... ... to protect victims in San Diego, California’s Gaslamp Quarter Plaza for five years ... Quarter Plaza actively monitor the area for any suspicious activity. These cameras are ...
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... scientific program at ATA’s 21st Annual Meeting and Tradeshow focused exclusively on telemedicine, ... than 300 cutting-edge health care technology vendors, will take place May 14-17, 2016 ...
(Date:7/30/2015)... ... July 30, 2015 , ... ... into one of the largest, family-owned low cost service and repair companies. For ... applications, as well as growing their company to meet the demands of the ...
Breaking Medicine News(10 mins):Health News:New Study Shows the Link between Hair Restoration and Healthy Self-Image 2Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 2Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 3Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 4Health News:Eyepartner Software Helps Victims in Gaslamp Quarter Plaza 2Health News:Eyepartner Software Helps Victims in Gaslamp Quarter Plaza 3Health News:Presentation Proposals for ATA 2016 are Now Being Accepted Online at ATA2016.com 2Health News:Presentation Proposals for ATA 2016 are Now Being Accepted Online at ATA2016.com 3Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 2Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 3
... , , , ... Corporation (ZixCorp(R)), (Nasdaq: ZIXI ), the leader in email encryption ... latest agreement is a two-year extension of Humana,s original agreement which has ... number of ZixCorp licenses bringing the total to 36,000. , ...
... , FARMINGDALE, N.Y., Sept. 2 ... of minimally invasive ultrasonic medical device technology, which in Europe ... other acute health conditions, today announced the restructuring and expansion ... have been created; one for sales and service of the ...
... PHILADELPHIA (September 2, 2009) The Fox Chase Cancer ... National Center for Research Resources of the National Institutes ... facility. The new facility will support advanced ... the way for the development of new treatments. The ...
... While the total mortality rate from unintentional injury increased in ... larger increases were seen in some subgroups analyzed by age, ... Johns Hopkins Bloomberg School of Public Health,s Center for Injury ... 45 and 64 years old experienced a 230 percent increase ...
... models to comb through thousands of injury reports in ... automatically classify them based on specific words or phrases. ... causes of injuries so that efforts could be directed ... Mark Lehto, an associate professor in Purdue University,s School ...
... approximately 20% of U.S. soldiers returning from Iraq and ... number with post-traumatic stress disorder (PTSD), and the high ... to Army commanders and the soldiers, families. Thanks ... will now be able to forecast a soldier,s chances ...
Cached Medicine News:Health News:Zix Corporation and Humana Renew and Expand Exclusive Agreement 2Health News:Misonix Restructures and Expands Sales Organization in Europe 2Health News:Misonix Restructures and Expands Sales Organization in Europe 3Health News:Misonix Restructures and Expands Sales Organization in Europe 4Health News:Fox Chase Cancer Center receives $8 million NIH grant to expand laboratory animal research facility 2Health News:Deaths from unintentional injuries increase for many groups 2Health News:New computer models aim to classify, help reduce injury accidents 2Health News:Keeping the suicidal soldier alive 2
(Date:7/30/2015)... , July 30, 2015 ... research report with market overview, trends, DRO ... porter analysis, recent developments, competitive scenario and ... Industry Insight: Biosensors Market Development and Demand ... http://photos.prnewswire.com/prnh/20150727/756778 ) Explore more ...
(Date:7/30/2015)... , July 30, 2015 Vermillion, ... on gynecologic disease, announced today it will ... after the market close on Thursday, August ... call and webcast at 4:30pm Eastern.Conference Call ... at 4:30pm Eastern/1:30pm Pacific  Domestic: ...
(Date:7/30/2015)... What can be expected from the ... grow at the fastest rates? Visiongain ,s brand ... data, trends, opportunities and prospects there. Our ... graphs. Discover the most lucrative areas in the industry ... you assess forecasted sales at overall world market and ...
Breaking Medicine Technology:Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 2Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 3Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 4Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 5Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 2Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 4Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 5Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 6
... 2011 The University of California, Los Angeles (UCLA) ... soon become the third oncology research center in the ... a privately held medical device company. ViewRay,s new research ... patented combination of radiotherapy delivery and simultaneous magnetic resonance ...
... Nearly three quarters of the medical ... from developed markets, but the next wave of growth is ... unique needs of the India market, according to preliminary findings ... which were presented today at AdvaMed 2011, the annual MedTech ...
Cached Medicine Technology:UCLA Health System - Jonsson Comprehensive Cancer Center to Acquire ViewRay Radiation Therapy Research System 2Made in India, for India, is Next Wave of Growth for Region's Medical Technology Sector 2Made in India, for India, is Next Wave of Growth for Region's Medical Technology Sector 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: