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Combination vaccines okay for infants, study shows
Date:10/3/2007

ws slow, and the programs, one by one, begin to terminate, Pichichero said. But those fears are unfounded; we have found no evidence that a childs body is at any point approaching a maximum threshold as far as learning to produce immune responses.

When you administer more vaccines, you expect more symptoms, more fevers, he said. Fever, swelling, redness are all indicators that the vaccine is working, that the body is busy creating the right immunity to prevent disease.

So long as they are mild, they pale in comparison to benefits of convenience to the parent, the fewer number of pokes to the infant, and of course, the severity of the diseases we are preventing, he said.

Perhaps most importantly, the study showed the Combination Vaccine Group enjoyed at least as good immunogenicity as the Separate and Staggered Groups, for all criteria including the criterion for protecting against whooping cough, for which previous, smaller-scale studies had yielded inconsistent results.

If pediatricians were holding out on making the switch to a combined vaccine for fear that its protection might be inferior, they no longer need be concerned, Pichichero said. It seems the clinical relevance of any previously observed differences with regard to whooping cough immunity have been dispelled.


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Contact: Becky Jones
rebecca_jones@urmc.rochester.edu
585-275-8490
University of Rochester Medical Center
Source:Eurekalert

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