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Combating the C. diff terrorists on the loose in hospitals
Date:5/19/2011

diff can naturally live with normal gut flora that aid in digestion and the production of vitamin K in the intestines.

But after a dose of broad-spectrum antibiotics that can destroy the good along with the bad bacteria in the intestines, C. diff has an opportunity to latch on to the walls of the gastrointestinal tract and start reproducing and releasing toxins.

As C. diff becomes heartier in its evolution, it has two particularly virulent toxins, known as A and B, which can cause bloating and severe diarrhea.

Many hospitals have antibiotic review boards to monitor antibiotic use to prevent over prescribing the drugs where not needed or to make recommendations to give an antibiotic that targets a specific bacteria instead of all bacteria.

Kenneley calls for these monitoring committees to become standard for all hospitals.

Instituting standard practices for all hospitals can be one way to stop this opportunistic infection from spreading to uninfected patients, she said.


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Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

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