Navigation Links
Coma and general anesthesia demonstrate important similarities
Date:12/29/2010

o part of the circuit is the basal ganglia, within the front of the brain, which is used to control certain actions. It does this in part by setting up two feedback loops. One is a negative feedback release on behavior, and that part of the circuit is always active when overall brain activity is reduced, Dr. Schiff says. For example, it works to stop a sleeping person from physically acting out their dreams.

The second feedback loop, however, releases the brake imposed by the first feedback loop, the researchers say. Certain drugs, such as the sleep aid zolpidem (Ambien), and propofol, a powerful general anesthetic with similar pharmacologic properties, can trigger that loop to function, producing what is known as "paradoxical excitation."

This phenomenon described in transitions observed in the early stages of general anesthesia appears to be common across all three states, because the drugs are triggering this same feedback loop, the authors explain. Most people given propofol become agitated and confused shortly after falling unconscious. Some people who use Ambien walk, eat and carry out other complex behaviors in an altered state of consciousness arising from sleep. Surprisingly, Ambien has also been reported to restore communication and behavioral responsiveness in some severely brain injured patients. The linkage of these disparate observations within a common circuit model is one of the key insights in the authors' integrative review.

Eventually the brake is switched back on in these three states -- giving way to sedation and deeper sleep, or in the case of the severely brain patient, the return to a state of diminished responsiveness.

There is another phenomenon that results from this circuit, the authors say. "Emergence delirium is the flip side," says Dr. Brown. "For example, when bringing a person out of general anesthesia, the brain is woken up enough to be active, but it is not coherent or organized, which can explai
'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Allegheny General Hospital Study Demonstrates Safety and Potential Efficacy of Oral Allergy Treatment
2. Tyco International to Host 2010 Annual General Meeting of Shareholders
3. AppDynamics Announces General Availability of AppDynamics v2.0
4. Surgeon General with Microsoft HealthVault Expands Consumer Benefits for the My Family Health Portrait Offering
5. RNs Praise Attorney General Move to Subpoena Insurance Plans
6. U.S. Surgeon General Regina Benjamin to Address National Association of Black Journalists Conference on Health Disparities
7. Coffee Is Generally Heart-Friendly
8. General Nutrition Centers, Inc. Reports Fourth Quarter 2009 Results
9. United Nations Secretary-General Ban Ki-moon, President Bill Clinton, Launch MASSIVEGOOD, a Citizen Solution for Funding Global Health
10. Delphi Healthcare Parners Announces New General Surgery Hospitalist Program with CarolinaEast Health System in New Bern, North Carolina
11. AdvancedMD Appoints William Stone Vice President and General Manager of Billing Services Partner Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... Analysis to 2023” focuses on the current treatment landscape, ... colorectal cancer market. TS-1 is an anti-cancer drug which ... administered orally and is also used for treating gastric ... gimestat and otastat potassium. The drug was first approved ...
(Date:12/25/2014)... December 25, 2014 The short film “Color ... created in honor of a true 9/11 hero, Welles Remy ... festivals including the 24 hours of Nuremberg International Short Film ... , Actress, screenwriter and director Luciana Lagana ... film together with her husband, Gregory Graham - ...
(Date:12/25/2014)... 25, 2014 Recently, LunaDress.co.uk has updated its blog ... related accessories. Now, all of the models at LunaDress.co.uk come with ... groom lifts the wedding veil can turn out to be a ... A wedding veil can always bring surprise to a wedding. On ... how to choose veils for a big day . , ...
(Date:12/25/2014)... HealthDay Reporter WEDNESDAY, Dec. 24, ... a "fountain of youth" drug that can delay the effects ... new study suggests. Seniors received a significant boost to ... genetic signaling pathway linked to aging and immune function, researchers ... experimental medication, a version of the drug rapamycin, improved the ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Residents ... Retirement Community, recently showed their generous spirit by ... the Catawba County Parenting Network- Grandparents Raising Grandchildren ... children gathered around the largest Christmas tree on ... presents purchased by residents of the Abernethy Village ...
Breaking Medicine News(10 mins):Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Retirement Community Residents Make Impact During Holiday Season 2
... cancer treatment center in Houston stated yesterday that ultrasound is ... cancer in pregnant woman. // ,Dr. Wei ... are hoping to educate young women that the symptomatic breast ... treated while pregnant, and so they should not wait to ...
... launched by the UK Government has been blamed for putting ... process. The Department of Health had proposed to introduce a ... 69 year olds. ,A significant delay has been ... funding and preparation, according to reports of the Cancer Research ...
... neurologist, co-director of the Muscular Dystrophy Association (MDA) ... neurology and pathology at Ohio State University College ... Program and Gene Therapy Center at Columbus Children’s ... Biopharmaceutical Inc (AskBio’s) Biostrophin, which contains a functional ...
... Kartar Singh have been sentenced to two years in jail for ... it if it was female.// This is the first time that ... determination tests and abortions. ,The perpetrators were found out ... Sabani was caught on audio and video telling one of the ...
... the heart and making a correct diagnosis cardiologists are ... students, residents, and other practicing physicians at performing a ... sounds. This was revealed by the findings of two ... ,The study was performed by Dr. Jasminka M. Vukanovic-Criley, ...
... be used for easing the debilitating pain from arthritis. // ... Shulov Institute of Sciences (SIS) in Israel where the research ... snake venom could be on sale within five years. ... most common snake in Israel - and said people suffering ...
Cached Medicine News:Health News:Delay In Life-Saving Bowel Cancer Screening Programme In UK 2Health News:Trial Of DMD Gene Therapy Initiated At Ohio 2
(Date:12/24/2014)... Wis. , Dec. 23, 2014 PuraMed ... marketer of over-the-counter (OTC) medicinal and healthcare products, announced ... of MigraPure® H, a hemp-based, advanced headache relief product, ... dispensaries in Colorado , ... . With the MigraPure H Advanced headache ...
(Date:12/24/2014)... , Dec. 23, 2014  Advanced Medical Isotope ... engaged primarily in the development of brachytherapy devices ... today announced that it has filed a ... Drug Administration ("FDA") for marketing clearance for its ... of the U.S. Food, Drug and Cosmetic Act ...
(Date:12/24/2014)... , December 24, 2014 ... Report on Global Disposable Syringe Industry of ... its online business intelligence library. ... Disposable Syringe Industry is a professional and ... market.  For overview analysis, the report introduces ...
Breaking Medicine Technology:PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
... WOONSOCKET, R.I., Dec. 11 CVS Caremark (NYSE: ... Senior Vice President and Chief Human Resources Officer, effective January ... announced his retirement. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090226/NE75914LOGO ) ... Caremark, has more than 30 years of human resources experience. ...
... , OXFORD, England, December 11 ... Ii Clinical Results With cat,Allergy T-cell Vaccine , ... Into,Late-Stage Development , Circassia Ltd, a ... completed a GBP15 million ($25 million),fundraising. The investment round, which ...
Cached Medicine Technology:CVS Caremark Names New Chief Human Resources Officer 2Circassia Raises GBP15 Million ($25 Million) in Oversubscribed Investment Round 2
... The SourceLink™ Delivery System offers ... implants. It addresses the challenges associated ... as provides the flexibility of seed ... Seeds packaged per customers desired quantity ...
... EXPRESS Seeding Cartridge System is a single-use, ... seeds and spacers into a Bard BrachyStar ... has a(n): outer radiation safety shield, inner ... spacers, integrally molded fitting that connects the ...
... to bring efficiency and quality to routine ... superior technology of fluorescent flow cytometry with ... sampling or batch processing are easily accommodated ... in high volume laboratories. Fluorescent flow ...
... The Quinton Q-Track II Holter Monitoring System ... that produced the worlds first true 12-lead ... 12-lead presentation of any beat contained in ... analysis. , ,The preprocessing work done by ...
Medicine Products: