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Colorectal cancer screening works
Date:9/27/2013

in exactly the same way as is happening with cervical cancer screening. We would also like to investigate the cost-effectiveness of CRC screening, since we believe that it has the potential to bring about economic gains associated with averted CRC cases and deaths, and hence to more than pay for its initial cost," says Prof Autier.

"If two-thirds of eligible people in each country attend screening, we believe that we could see a considerable reduction in CRC mortality in a minimum of ten years. National healthcare services need to put more effort into organising screening programmes based on FOBT or endoscopy, and into informing people aged 50 and over about the availability of these tests so that they can make a choice."

The evidence for the reduction in mortality from CRC screening programmes is just as strong as it is for cervical cancer, the researchers say. It is strengthened by the fact that there are major differences between countries where health care is of similar quality, which can only be attributed to the differences in screening rates. For example, 34% of men in France aged 50 or more and 12% of men in the same age group in The Netherlands had an endoscopic screening during the period studied. Between 1996 and 2009, CRC mortality decreased by 31% in men in France but the decrease in men in The Netherlands was only 4% over the same period. A similar pattern was seen in women from the two countries.

"There is a clear relationship between randomised trials showing the ability of any type of CRC screening to reduce the risk of death from the disease, data from cancer registries showing declines in the incidence of advanced CRC, and declines in CRC mortality over time. In breast cancer, there is no such smooth logical sequence between randomised trials and these population statistics. It seems to us that there is now an irrefutable case for devoting some of the resources from breast and prostate cancer screening to the early det
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Contact: Mary Rice
mary.rice@riceconseil.eu
ECCO-the European CanCer Organisation
Source:Eurekalert

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