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Colonoscopy screening reduces risk of advanced colorectal cancer
Date:3/5/2013

Philadelphia - A new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania adds support to current medical recommendations stating that screening colonoscopy substantially reduces an average-risk adults likelihood of being diagnosed with advanced colorectal cancer (CRC) in either the right or left side of the colon. In recent years, colonoscopy has begun to rapidly replace sigmoidoscopy a procedure used to detect abnormalities in the rectum and left side of the colon despite initially limited evidence of its efficacy and higher cost. In the new study, researchers noted an overall 70 percent reduction of advanced CRC diagnoses associated with receiving a screening colonoscopy. The results of the study suggest that colonoscopy has the ability to effectively identify tumors in both the left and right side of the colon before they progress to an advanced stage. The full results of the study appear online in the Annals of Internal Medicine.

Previous research has established that screening with sigmoidoscopy or fecal occult blood test reduces the risk of death from colorectal cancer. By contrast, the efficacy of the colonoscopy which examines the entire colon for precancerous and cancerous growths in average-risk adults has remained largely uncertain. Colonoscopys effectiveness in the right colon (where approximately 50 percent of new CRC cases in the U.S. are found) has remained in doubt.

Colorectal cancer is one of the most important cancers we face in this country. It was responsible for over 50,000 deaths in 2012, and the truth is, most of those deaths are preventable through screening, early detection, and treatment, said Chyke Doubeni, MD, MPH, presidential associate professor of Family Medicine and Community Health at Penn Medicine, and lead author on the study. Our goal with this study was
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Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine
Source:Eurekalert

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