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Colonoscopy screening markedly reduces colorectal cancer incidence and death
Date:7/24/2012

OAK BROOK, Ill. JULY 24, 2012 A study from researchers in Switzerland found that colonoscopy with polypectomy significantly reduces colorectal cancer incidence and colorectal cancer-related death in the general population. A total of 12 colorectal cancer cases were identified in the screening group of 1,912 patients and 213 cases of colorectal cancer were found in the non-screened group of 20,774 patients. One of the 12 persons of the screened individuals with a colorectal cancer and 51 of the 213 persons of the non-screened individuals with a colorectal cancer died because of their cancers. The study appears in the July issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

Colorectal cancer (CRC) has a very high incidence in Switzerland as well as in other European countries and is the second most frequent cause of cancer-related deaths in Europe. It is detected in approximately 413,000 people in Europe every year, half of whom die because of the disease. Therefore a need exists for efficient strategies for prevention and early detection of CRC. Colonoscopy with the possibility of an immediate polypectomy is a recommended and preferred screening method because polyps (growths in the colon) can turn into cancer over the course of years to decades. Removing polyps during a colonoscopy prevents that polyp from becoming cancerous.

"In contrast to earlier CRC screening studies that used colonoscopy, this population-based closed cohort observational study aimed to obtain complete and comparable data on CRC incidence and CRC-related mortality after a single screening colonoscopy compared with no screening, while taking into account the potential differences in risk profiles between the screened and non-screened participants," said study lead author Urs A. Marbet, Cantonal Hospital of Uri, Altdorf, Switzerland. "We found that colorectal cancer s
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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