Navigation Links
Colonoscopy prevents deaths from colon cancer
Date:2/23/2012

For the first time, a new study has shown that removing polyps by colonoscopy not only prevents colorectal cancer from developing, but also prevents deaths from the disease. Patients in the study were evaluated for up to 23 years after having the procedure, providing the longest follow-up results to date. The collaborative study, led by researchers at Memorial Sloan-Kettering Cancer Center, will be published in the February 23, 2012 issue of The New England Journal of Medicine.

"Our findings provide strong reassurance that there is a long-term benefit to removing these polyps and support continued recommendations of screening colonoscopy in people over age 50," said the study's lead author Ann G. Zauber, PhD, a biostatistician at Memorial Sloan-Kettering.

Tumor-like growths called adenomatous polyps are the most common abnormality found during colonoscopy screening and have the potential to become cancerous. Previous research from these investigators showed that removal of these polyps prevented colorectal cancer but it was not known whether the cancers prevented were potentially lethal. This study assessed whether removal of adenomatous polyps reduced colorectal cancer mortality a finding that would indicate that the polyps removed had the potential to progress and cause cancer death.

Researchers evaluated the long-term results of 2,602 patients enrolled in the National Polyp Study (NPS, the largest study of its kind) who had precancerous polyps removed during colonoscopy. They found that the detection and removal of these lesions resulted in a 53 percent reduction in colorectal cancer mortality compared to that of the deaths expected in the general population of comparable size, age, and gender. Furthermore, patients who had adenomatous polyps removed also had the same low death rate from colorectal cancer for up to 10 years after the procedure compared to a control group of people in whom no such polyps were detected.

"The magnitude of reduction in mortality seen after this procedure is likely due to high-quality colonoscopy performed by well-trained, experienced gastroenterologists," said the study's senior author Sidney J. Winawer, MD, a gastroenterologist at Memorial Sloan-Kettering and Principal Investigator of the NPS. "Randomized controlled trials of screening colonoscopy in the general population underway in the US and Europe will in 10 to 15 years provide further evidence for this potentially powerful cancer prevention approach," added Dr. Winawer, an internationally recognized leader in the prevention of digestive cancers who is credited with introducing colonoscopy as a key component of national guidelines for colorectal cancer screening in the United States and worldwide.

The National Cancer Institute estimates that in 2011 more than 100,000 new cases of colon cancer and almost 40,000 cases of rectal cancer were diagnosed, and that more than 49,000 people died from colon and rectal cancer combined.

The multi-institutional study included experts from various disciplines, including endoscopists, radiologists, pathologists, and epidemiologists. Researchers from the following institutions contributed to the study: Boston University School of Medicine (MA), Erasmus Medical Center (Netherlands), Minneapolis Veterans Administration (MN), Valley Presbyterian Hospital (CA), Cedars Sinai Medical Center (CA), Medical College of Wisconsin (WI), and Mount Sinai Medical Center (NY).


'/>"/>

Contact: Esther Napolitano
napolite@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Related medicine news :

1. CT colonography shown to be comparable to standard colonoscopy
2. Colon Cancer Alliance and American College of Radiology demand Medicare cover virtual colonoscopy
3. Recession and high co-pays tied to fewer colonoscopy screenings among people with health insurance
4. Worries About Colonoscopy Unfounded: Study
5. Alternative to Colonoscopy Spots Cancers, Too
6. Study examines quality of colonoscopy reporting and performance
7. Colon cancer screening campaign erases racial, gender gaps in use of colonoscopy
8. Fecal occult blood testing effective in colonoscopy screenings
9. Physicians who play Mozart while performing colonoscopy may improve adenoma detection rate
10. Virtual Colonoscopy Still Has Its Skeptics
11. Colonoscopy Better Than Alternative at Spotting Cancer in Seniors: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/6/2016)... ... December 06, 2016 , ... SPH ... firms. The ranking is based on reported data for 2015 performance and ... systems, ambulatory surgical centers, clinically integrated networks, and many of the nation’s leading ...
(Date:12/6/2016)... ... 06, 2016 , ... The Behavioral Health Center of Excellence ... organization as a top behavioral service provider in the country. The award celebrates ... satisfaction and qualifications, and consumer satisfaction. These areas are measured via a wide-ranging ...
(Date:12/6/2016)... ... December 06, 2016 , ... Just in time for the holiday season, ... chip cookie recipe for Honeyville’s new Organic Quinoa Flour product for sale at Costco ... the near future. , “I think it’s wonderful that a growing number of ...
(Date:12/6/2016)... ... ... Keeping Gift Season Safe, In a season stacked with gift-giving opportunities, it's ... recipients. This is the idea behind Safe Toys and Gifts Month, which sets aside ... good gifts for children. For companies that produce goods that fall into this category, ...
(Date:12/6/2016)... Viejo, California (PRWEB) , ... December 06, 2016 , ... ... allows users to flicker, flash, and flare from clip to clip with high quality ... , TransFlare 4K Jewel contains 44 lens flares filmed on the RED Dragon. ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... 2016  Balloon catheter is an innovative medical device ... the femoral artery in the leg or sometimes into ... blood vessels. These products are generally used to prevent ... of lipid substances in the blood vessel. In terms ... to expand at a CAGR of 3.8% during the ...
(Date:12/5/2016)... Kingdom , Dec. 5, 2016   Mallinckrodt ... global specialty pharmaceutical company, today announced that it received ... Corporate Equality Index (CEI), a national benchmarking survey and ... gay, bisexual and transgender (LGBT) workplace equality, administered by ... ranks of 517 major U.S. businesses which also earned ...
(Date:12/5/2016)...  Parallax Health Sciences, Inc. ("Parallax" or the "Company") ... pharmaceutical business, RoxSan Pharmacy, Inc. has received a license ... of the 42 states it is currently licensed to ... Pharm . D, Pharmacist in Charge at RoxSan Pharmacy, ... Medicare B spending last year came to roughly $170 ...
Breaking Medicine Technology: