Navigation Links
Colonoscopy prevents deaths from colon cancer
Date:2/23/2012

For the first time, a new study has shown that removing polyps by colonoscopy not only prevents colorectal cancer from developing, but also prevents deaths from the disease. Patients in the study were evaluated for up to 23 years after having the procedure, providing the longest follow-up results to date. The collaborative study, led by researchers at Memorial Sloan-Kettering Cancer Center, will be published in the February 23, 2012 issue of The New England Journal of Medicine.

"Our findings provide strong reassurance that there is a long-term benefit to removing these polyps and support continued recommendations of screening colonoscopy in people over age 50," said the study's lead author Ann G. Zauber, PhD, a biostatistician at Memorial Sloan-Kettering.

Tumor-like growths called adenomatous polyps are the most common abnormality found during colonoscopy screening and have the potential to become cancerous. Previous research from these investigators showed that removal of these polyps prevented colorectal cancer but it was not known whether the cancers prevented were potentially lethal. This study assessed whether removal of adenomatous polyps reduced colorectal cancer mortality a finding that would indicate that the polyps removed had the potential to progress and cause cancer death.

Researchers evaluated the long-term results of 2,602 patients enrolled in the National Polyp Study (NPS, the largest study of its kind) who had precancerous polyps removed during colonoscopy. They found that the detection and removal of these lesions resulted in a 53 percent reduction in colorectal cancer mortality compared to that of the deaths expected in the general population of comparable size, age, and gender. Furthermore, patients who had adenomatous polyps removed also had the same low death rate from colorectal cancer for up to 10 years after the procedure compared to a control group of people in whom no such polyps were detected.

"The magnitude of reduction in mortality seen after this procedure is likely due to high-quality colonoscopy performed by well-trained, experienced gastroenterologists," said the study's senior author Sidney J. Winawer, MD, a gastroenterologist at Memorial Sloan-Kettering and Principal Investigator of the NPS. "Randomized controlled trials of screening colonoscopy in the general population underway in the US and Europe will in 10 to 15 years provide further evidence for this potentially powerful cancer prevention approach," added Dr. Winawer, an internationally recognized leader in the prevention of digestive cancers who is credited with introducing colonoscopy as a key component of national guidelines for colorectal cancer screening in the United States and worldwide.

The National Cancer Institute estimates that in 2011 more than 100,000 new cases of colon cancer and almost 40,000 cases of rectal cancer were diagnosed, and that more than 49,000 people died from colon and rectal cancer combined.

The multi-institutional study included experts from various disciplines, including endoscopists, radiologists, pathologists, and epidemiologists. Researchers from the following institutions contributed to the study: Boston University School of Medicine (MA), Erasmus Medical Center (Netherlands), Minneapolis Veterans Administration (MN), Valley Presbyterian Hospital (CA), Cedars Sinai Medical Center (CA), Medical College of Wisconsin (WI), and Mount Sinai Medical Center (NY).


'/>"/>

Contact: Esther Napolitano
napolite@mskcc.org
212-639-3573
Memorial Sloan-Kettering Cancer Center
Source:Eurekalert

Related medicine news :

1. CT colonography shown to be comparable to standard colonoscopy
2. Colon Cancer Alliance and American College of Radiology demand Medicare cover virtual colonoscopy
3. Recession and high co-pays tied to fewer colonoscopy screenings among people with health insurance
4. Worries About Colonoscopy Unfounded: Study
5. Alternative to Colonoscopy Spots Cancers, Too
6. Study examines quality of colonoscopy reporting and performance
7. Colon cancer screening campaign erases racial, gender gaps in use of colonoscopy
8. Fecal occult blood testing effective in colonoscopy screenings
9. Physicians who play Mozart while performing colonoscopy may improve adenoma detection rate
10. Virtual Colonoscopy Still Has Its Skeptics
11. Colonoscopy Better Than Alternative at Spotting Cancer in Seniors: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... San Diego, CA (PRWEB) , ... June 24, 2016 , ... ... up with the American Cancer Society and the Road To Recovery® program to drive ... care to seniors and other adults to ensure the highest quality of life and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... PUNE, India , June 24, 2016 ... "Pen Needles Market by Type (Standard Pen Needles, Safety ... 12mm), Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase ... published by MarketsandMarkets, This report studies the market for ... is expected to reach USD 2.81 Billion by 2021 ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
Breaking Medicine Technology: