Navigation Links
Colon cancer and the microbes in your gut
Date:3/30/2009

A typical Western diet, rich in meat and fats and low in complex carbohydrates, is a recipe for colon cancer, Professor Stephen O'Keefe from the University of Pittsburgh, USA, told the Society for General Microbiology meeting at Harrogate today (Tuesday 31 March). He described an expanding body of evidence to show that the composition of the diet directly influences the diversity of the microbes in the gut, providing the link between diet, colonic disease and colon cancer.

People eating a healthy diet containing high levels of complex carbohydrate had significant populations of micro-organisms in their gut called Firmicutes. These bacteria use the undigested residues of starch and proteins in the colon to manufacture short-chain fatty acids and vitamins such as folate and biotin that maintain colonic health. One of these fatty acids, butyrate, not only provides most of the energy to maintain a healthy gut wall, but it also regulates cell growth and differentiation. Both experimental and human studies support its role in reducing colon cancer risk.

However, gut microbes may also make toxic products from food residues. Diets high in meat will produce sulphur - this decreases the activity of 'good' bacteria that use methane and increases the production of hydrogen sulphide and other possible carcinogens by sulphur-reducing bacteria.

"Colon cancer is the second leading cause of cancer-related deaths in adults in Westernized communities." said Professor O'Keefe, "Our results suggest that a diet that maintains the health of the colon wall is also one that maintains general body health and reduces heart disease".

"A diet rich in fibre and resistant starch encourages the growth of good bacteria and increases production of short chain fatty acids which lessen the risk of cancer, while a high meat and fat diet reduces the numbers of these good bacteria." Professor O'Keefe went on. "Our investigations to date have focused on a small number of bacterial species and have therefore revealed but the tip of the iceberg, our colons harbour over 800 bacterial species and 7,000 different strains. The characterization of their properties and metabolism can be expected to provide the key to colonic health and disease".


'/>"/>

Contact: Dianne Stilwell
d.stilwell@sgm.ac.uk
44-795-720-0214
Society for General Microbiology
Source:Eurekalert

Related medicine news :

1. Germany: Colonoscopy prevents 15,000 cancer cases
2. What to Expect From a Colonoscopy
3. Pitt vaccine to prevent colon cancer being tested in patients
4. Northern California Cancer Center Study Seeks to Improve Colon Cancer Screening in Vietnamese Communities
5. Econiche(TM) Vaccine Shows 92% Reduction in Colonization of E. coli O157 in Vaccinated Cattle
6. Understand Colon Cancer with MyBiopsy.Org; Schedule a Screening Test at MyHealthTestReminder.Org
7. Keep Your Colon Healthy With Exercise, Healthy Foods
8. Water method for unsedated colonoscopy; interval between prep and colonoscopy predicts prep quality
9. Local Gastroenterology Practice Gives Back to the Community During Colon Cancer Awareness Month
10. Free Video for Health Care Providers and Patients Who are Preparing for a Colonoscopy Is Now Available at www.TriLyte.com
11. Mail and electronic reminders may increase colon cancer screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned ... the David Geffen School of Medicine at UCLA. He trained in Internal Medicine at ... fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... 2022" report to their offering. ... with kidney failure, it replaces the function of kidneys by ... and thus the treatment helps to keep the patient body,s ... Increasing number of ESRD patients & substantial healthcare ...
Breaking Medicine Technology: