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Collagen-deficient mice show signs of osteoarthritis
Date:8/26/2009

also had elevated levels of knee and intervertebral disc structural changes.

According to the study, collagen deficient mice chose movements that limited peak joint forces and behaviors that reduced pain sensations. "In future work, these measures may help track signs and symptoms as degeneration progresses," added Dr. Allen. "Further studies of the mouse model could provide useful data for evaluating the efficacy of therapeutic interventions for musculoskeletal disorders."


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Contact: Dawn Peters
medicalnews@wiley.com
Wiley-Blackwell
Source:Eurekalert

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