Navigation Links
Collaborative Drug Discovery, Inc. and St. Jude Children's Research Hospital Make Malaria Research Data Available to Speed Drug Development
Date:10/11/2007

SAN FRANCISCO, Oct. 11 /PRNewswire/ -- Collaborative Drug Discovery, Inc. (CDD, Inc.) and St. Jude Children's Research Hospital have joined together for a project aimed at speeding the development of new drugs to overcome resistant strains of malaria.

The collaboration combines the malaria drug data and informatics technology of CDD with the drug discovery expertise of the St. Jude Department of Chemical Biology and Therapeutics. Informatics is the use of computer hardware and software to extract and manage knowledge from large databases.

"CDD's databases will probably help us reduce the number of potential molecules we'll need to analyze from tens of millions down to hundreds of thousands," said Kip Guy, Ph.D., chair of the St. Jude Department of Chemical Biology and Therapeutics. "Our own screening capability will significantly reduce that to a much smaller number of promising compounds. This will be a widely used database. We are already making the data freely available through CDD so that other researchers can use different analytical strategies to identify potential new anti-malarial drugs."

The collaboration is designed to help scientists quickly screen millions of chemicals, based on their structure and their chemical and biological properties, to find those that are most likely to make effective anti-malaria drugs. The key to this quest to find the drug "needle in the haystack" is the enormous two-volume collection of data from studies on malarial drugs published by the U.S. Army in 1946.

This 61-year-old publication, "A Survey of Malaria Drugs," was originally edited by Frederick Y. Wiselogle and had contributions from a number of leading researchers of the time. The two-volume set was designed to help researchers develop effective anti-malarial drugs; and to serve as a model for how scientists could develop drugs for other infections, according to the authors of that publication. The collection presents the structures of many
'/>"/>

SOURCE Collaborative Drug Discovery, Inc.; St. Jude Children'sResearch
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. WHO And China Set Up Collaborative Center For Fighting Bird Flu
2. Collaborative use of Imaging Techniques proved effective in Cardiovascular Diagnosis – ESC Recommend
3. Medarex Announces Collaborative Research Agreement With Mitsubishi Pharma
4. Tuberculosis – 125 Years Since Discovery, Yet a Challenge to Dat
5. RSV Hits Winnipeg Childrens Hospital
6. Coverage for Childrens Mental Illness Reduces Out-of-Pocket Spending
7. Childrens Health Program Covering More Adults Than Children
8. Nutritious Diet Help Improve Childrens Academic Performance
9. Kidney Stones - Interesting New Research implicates bacteria as its cause
10. Stem cell research- now Nobel Laureates join the debate
11. Researchers urge caution in using ear tube surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... CITY, GA (PRWEB) September 02, 2014 Last ... whole new level with the launch of a luxurious line ... to announce that the SEA ISLAND COTTON Socks are joining ... compression level, giving more people the comfort of natural cotton ... COTTON Socks, they are surprised to find socks as soft ...
(Date:9/2/2014)... FL (PRWEB) September 02, 2014 Alliance ... targeting and multi-channel email marketing is pleased to announce ... market, Firearms & Freedom as well as ... properties represent more than one million concerned Americans who ... advertising. , “We are honored to continue providing ...
(Date:9/2/2014)... hospitalized, but your outpatient doctor does not know? ... follow-up care, but your doctor does not have ... Missing or incomplete communication from hospitals to outpatient ... experiences and lead to hospital readmissions. , ... can improve hospitals, communication during patient care transitions. ...
(Date:9/2/2014)... many health risks, including heart disease and diabetes, but ... to mitigate one often-overlooked risk: not buckling up in ... H. Jacobson, a professor of computer science and of ... with a decrease in seatbelt usage. However, these effects ... , "Primary seatbelt laws lead to increased use of ...
(Date:9/2/2014)... Farmington, New York (PRWEB) September 02, 2014 ... Millworks is making it easy to create a consistent look ... the physical structure, to the floor you walk on and ... shop for all custom reclaimed wood designs. , “We’re ... customers to our product line. It saves time, adds consistency, ...
Breaking Medicine News(10 mins):Health News:SIGVARIS’ Luxury Line of Compression Socks, SEA ISLAND COTTON, Now Available in Stronger Compression Level 2Health News:ASG Continues to Bring New Lists to Market 2Health News:ASG Continues to Bring New Lists to Market 3Health News:Can data motivate hospital leaders to improve care transitions? 2Health News:Seatbelt laws encourage obese drivers to buckle up 2Health News:Pioneer Millworks Now Offering Products Beyond Reclaimed Wood Flooring 2
... The Advertising Standards Authority ruled yesterday that a Walkers ... salt content.// ,According to the industry watchdog ... in its crisps to "7% of your guideline daily ... did not apply to all Walkers crisps. They have ...
... scheme launched in Madhya Pradesh to help malnourished children is ... Shakti scheme was unveiled to aid the 5.7 million malnourished ... years in age, Grassroots Features reported. ,Two-and-a-half-year-old Prem ... 4.2 kg when she was brought to the Bal Shakti ...
... to a new study at the University of Michigan Depression ... not getting// any treatment nor are the ones with the ... ,In the latest issue of General Hospital Psychiatry, the ... of treatment, are not getting enough. ,Without adequate treatment ...
... Bill Gates said inadequate access to treatment and continued discrimination ... in addresses to the largest ever AIDS conference under way ... stigma and stop people from being scared to know their ... Gates have donated billions of dollars to combat the spread ...
... the use of Herceptin in advanced breast cancer patients led ... percent of patients treated with Herceptin// , which no ... of the damage to the heart can be remedied with ... in the Journal of Clinical Oncology, concludes that use of ...
... that reduced levels of testosterone, which is the male sex ... whether a man would die early. ,US scientists ... 858 military veterans aged over 40. Reporting their findings in ... low hormone levels had an 88% increased risk of death ...
Cached Medicine News:Health News:Scheme for Combating Malnourishment in MP Children Yet to Pick Up 2Health News:No therapy for most of the pregnant women with depression 2Health News:No therapy for most of the pregnant women with depression 3Health News:No therapy for most of the pregnant women with depression 4Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 2Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 3Health News:Low Testosterone Linked With Early Death 2
(Date:9/2/2014)...  Boston Scientific Corporation (NYSE: BSX ... purchase the Interventional business of Bayer AG. The ... offer physicians and healthcare systems a more complete ... The addition of the Bayer Interventional ... Boston Scientific strategy to provide a comprehensive portfolio ...
(Date:9/2/2014)... , Sept. 2, 2014  Volcano Corporation ... focused on improving patient and economic outcomes on ... minimally invasive coronary and peripheral visualization, physiology diagnostics ... participating in the Morgan Stanley Healthcare conference on ... Scott Huennekens , president and chief executive ...
(Date:9/2/2014)... SAN DIEGO , Sept. 2, 2014  Arena ... that the US Food and Drug Administration (FDA) has ... of pulmonary arterial hypertension. "The FDA ... clinical data submissions from sponsors to identify and designate ... help advance the evaluation and development of such products," ...
Breaking Medicine Technology:Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 2Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 3Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 4Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 5Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 2Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 3Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: