Navigation Links
Collaborative Drug Discovery, Inc. and St. Jude Children's Research Hospital Make Malaria Research Data Available to Speed Drug Development
Date:10/11/2007

SAN FRANCISCO, Oct. 11 /PRNewswire/ -- Collaborative Drug Discovery, Inc. (CDD, Inc.) and St. Jude Children's Research Hospital have joined together for a project aimed at speeding the development of new drugs to overcome resistant strains of malaria.

The collaboration combines the malaria drug data and informatics technology of CDD with the drug discovery expertise of the St. Jude Department of Chemical Biology and Therapeutics. Informatics is the use of computer hardware and software to extract and manage knowledge from large databases.

"CDD's databases will probably help us reduce the number of potential molecules we'll need to analyze from tens of millions down to hundreds of thousands," said Kip Guy, Ph.D., chair of the St. Jude Department of Chemical Biology and Therapeutics. "Our own screening capability will significantly reduce that to a much smaller number of promising compounds. This will be a widely used database. We are already making the data freely available through CDD so that other researchers can use different analytical strategies to identify potential new anti-malarial drugs."

The collaboration is designed to help scientists quickly screen millions of chemicals, based on their structure and their chemical and biological properties, to find those that are most likely to make effective anti-malaria drugs. The key to this quest to find the drug "needle in the haystack" is the enormous two-volume collection of data from studies on malarial drugs published by the U.S. Army in 1946.

This 61-year-old publication, "A Survey of Malaria Drugs," was originally edited by Frederick Y. Wiselogle and had contributions from a number of leading researchers of the time. The two-volume set was designed to help researchers develop effective anti-malarial drugs; and to serve as a model for how scientists could develop drugs for other infections, according to the authors of that publication. The collection presents the structures of many
'/>"/>

SOURCE Collaborative Drug Discovery, Inc.; St. Jude Children'sResearch
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. WHO And China Set Up Collaborative Center For Fighting Bird Flu
2. Collaborative use of Imaging Techniques proved effective in Cardiovascular Diagnosis – ESC Recommend
3. Medarex Announces Collaborative Research Agreement With Mitsubishi Pharma
4. Tuberculosis – 125 Years Since Discovery, Yet a Challenge to Dat
5. RSV Hits Winnipeg Childrens Hospital
6. Coverage for Childrens Mental Illness Reduces Out-of-Pocket Spending
7. Childrens Health Program Covering More Adults Than Children
8. Nutritious Diet Help Improve Childrens Academic Performance
9. Kidney Stones - Interesting New Research implicates bacteria as its cause
10. Stem cell research- now Nobel Laureates join the debate
11. Researchers urge caution in using ear tube surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... some high-profile athletes who suffered repeated blows to the ... their brains. Those clumps suggest the athletes had a ... working on tests that might be able to detect ... in Chemical & Engineering News (C&EN) , the ... In the article, Lauren Wolf, a senior editor at ...
(Date:7/23/2014)... to a new market research report of "Semiconductor (Silicon) ... IP), Design Architecture (Hard IP, Soft IP), Processor Type ... & Analysis to 2013 - 2020", the semiconductor (silicon) ... of 12.6% from 2014 to 2020 and reach $5.63 ... data tables with 60 figures spread through 337 pages ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 The Centers for ... in prescription drug deaths from 2010 to 2012. Formerly ... its minimal monitoring of access to some of the strongest ... hands. Florida’s law enforcement launched an initiative to crack ... nonexistent compared to the 65 that existed in the state ...
(Date:7/23/2014)... East Asian women has identified three genetic changes linked ... led by Vanderbilt University investigators, was published online July ... cancer is one of the most common malignancies among ... for the disease have focused on women of European ... environmental exposures between East Asian women and those of ...
(Date:7/23/2014)... The Circuelle Foundation compiled and released ... the importance of breast self-exams (BSE). The historical ... self-exams is contradictory and can be confusing at ... this healthy ritual. , “Women are confused and ... breast self-exams and becoming breast aware,” explains Melissa ...
Breaking Medicine News(10 mins):Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 5Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 6Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 2Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 3Health News:Florida’s Crackdown on Pill Mills Has Led to Rise in Popularity of Synthetic Drugs; Suncoast Rehab Educates on Dangers of These Drugs in Adolescents 4Health News:Vanderbilt-led study identifies genes linked to breast cancer in East Asian women 2Health News:Historical and Current Research Points to Importance of Breast Self-Exams 2
... trial has shown that a diet loaded with fruits, ... to standard federal dietary recommendations cuts the risk of ... women who didn,t have hot flashes by ... and lower survival rates than breast cancer patients who ...
... Dec. 15 Pets Best Insurance LLC (Pets Best) ... will be underwritten by Aetna Insurance Company of Connecticut ... North Dakota and Texas. The change will strengthen Pets ... better platform for the continued growth of its mission ...
... 2008, Inverness Medical Innovations, Inc. (Amex: IMA ), ... solutions, declared a dividend of $3.00 per share on its ... will be paid in shares of Series B stock in ... $3.00 divided by (b) 97% of the average of the ...
... LAVAL, QC, Dec. 15 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: ... webcast presentation on, Tuesday, December 16, 2008, at 10:00 ... will discuss the product profile, clinical and regulatory progress ... of trazodone (DDS-04A), a serotonin antagonist reuptake inhibitor (SARI), ...
... 15 Robbins & Myers, Inc.,(NYSE: RBN ) ... January,8, 2009, its first quarter results for fiscal 2009 which ... conference call will be held at 10:00 a.m., ET,on Friday, ... C. Wallace,President and Chief Executive Officer, and Christopher M. Hix, ...
... McDonald,s , Nurses Call on County to Halt ... 15 The nation,s largest nurses union today charged that Jackson ... state law that protects employee rights, and is calling on Miami-Dade ... agreement between the hospital system and SEIU. , ...
Cached Medicine News:Health News:Diet may cut second breast cancers in women without hot flashes 2Health News:Diet may cut second breast cancers in women without hot flashes 3Health News:Pets Best Announces New Underwriter for Pet Insurance Policies 2Health News:Pets Best Announces New Underwriter for Pet Insurance Policies 3Health News:Labopharm to host webcast presentation on novel trazodone formulation - tomorrow (Dec.16/08) at 10:00 a.m. ET 2Health News:Labopharm to host webcast presentation on novel trazodone formulation - tomorrow (Dec.16/08) at 10:00 a.m. ET 3Health News:Labopharm to host webcast presentation on novel trazodone formulation - tomorrow (Dec.16/08) at 10:00 a.m. ET 4Health News:RNs Charge Jackson Health System, Service Union Broke State Law in Harassment of Hospital Nurses 2Health News:RNs Charge Jackson Health System, Service Union Broke State Law in Harassment of Hospital Nurses 3
(Date:7/23/2014)... -- Use of Risk Evaluation and Mitigation Strategies (REMS) ... entry results in $5.4 billion in lost savings annually, ... by economic consulting firm Matrix Global Advisors ... Required by the Food and Drug Administration (FDA) ... intended to improve drug safety by ensuring that the ...
(Date:7/23/2014)... 2014 /PRNewswire-iReach/ -- Top Staten Island Pediatrician Dr. ... on article, which discusses tips for parents about pool safety ... According to US News article, "Drowning ... American children aged 1 to 4, and can occur in ... expert in the article says that watching a child in ...
(Date:7/23/2014)... , July 23, 2014 PositiveID Corp. (OTCQB: ... , is an emerging player in the ... for bio-threat detection and rapid medical testing. The ... (Microfluidic Bio-agent Autonomous Networked Detector), was developed under ... ("DHS") Science & Technology directorate, and $30 million ...
Breaking Medicine Technology:New Analysis Finds $5.4 Billion In Annual Lost Savings From Strategies Geared Toward Delaying Generic Drug Entry 2Premier Staten Island Pediatrician Dr. Michael Gabriel Comments On Article Discussing Pool Safety Tips for Parents 2PositiveID Analyst Inspection: Emerging Contender in BioThreat Detection - First Ever Revenue Guidance and Backlog Position Company for Increased Visibility and Traction - by SmallCapTraders.com 2
... , SAN JOSE, Calif. ... a non-profit organization of medical professionals dedicated to advancing the ... its 2010 CyberKnife Society Scientific Meeting will be held ... Dallas, Texas .   , The CyberKnife Society Scientific ...
... , , PRINCETON, N.J. , ... in evidence-based compliance solutions, today announced a strategic alliance ... device manufacturers comply with the growing body of state ... reporting laws. As part of the alliance, R-Squared,s state-of-the-art ...
Cached Medicine Technology:CyberKnife Society Scientific Meeting to Highlight Clinical Results and Technical Innovations 2CyberKnife Society Scientific Meeting to Highlight Clinical Results and Technical Innovations 3R-Squared Forms Strategic Relationship with IMS Health 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: