Navigation Links
Cold Viruses Appear Linked to Type 1 Diabetes
Date:2/4/2011

By Steven Reinberg
HealthDay Reporter

THURSDAY, Feb. 3 (HealthDay News) -- While the causes of type 1 diabetes aren't known for certain, a new analysis backs the possibility that cold-like viruses might trigger the disease.

Australian researchers looked at a number of studies, and concluded there is a strong association between enteroviruses and the development of type 1 diabetes. In fact, children with diabetes were 10 times more likely to have had an enterovirus infection than children without the disease.

"The finding implies that enterovirus infection is a very important cause of type 1 diabetes," said lead researcher Dr. Maria Craig, an associate professor at Children's Hospital at Westmead's Institute of Endocrinology and Diabetes in Sydney.

Craig noted that the idea that enteroviruses are involved in the development of type 1 diabetes is not new, but this study makes use of new data that makes the association more likely.

"It is time to look at how these viruses are involved in the disease process," Craig said. The goal would be to find a way to "stop these viruses from contributing to diabetes -- potentially leading to vaccination," she added.

The report is published in the Feb. 3 online edition of the BMJ.

For the study, Craig's team, using a type of research known as a meta-analysis, reviewed 24 papers and two abstracts involving 4,448 individuals to see if there was an association between type 1 diabetes and enterovirus infection.

The data suggested a strong association, especially among children, Craig said.

Type 1 diabetes is caused by a combination of genetic factors, the immune system and environmental factors, the researchers explained. And enteroviruses are common viruses in infants and children. Enteroviruses can cause cold or flu symptoms, fever, muscle aches, rash or even meningitis, they noted.

Recently, there has been a worldwide increase in the incidence of childhood type 1 diabetes, especially in children under 5, which could be partially because of more exposure to these viruses, the researchers suggested.

Dr. Didier Hober, a professor of virology at University Lille in France and author of an accompanying journal editorial, said "the increased incidence rate of type 1 diabetes can be explained by a role of environmental factors, especially enteroviruses, like coxsackievirus B."

However, it is unclear whether enteroviruses are involved in all patients or just some, he added. "Enteroviruses could act as inducers of the disease or as accelerators of the progression of the disease. A persistent infection or consecutive infections could play a role," he said.

"The relationship between enteroviruses and type 1 diabetes opens up the possibility of developing new preventive and therapeutic strategies to fight the disease," Hober said.

Another expert, Dr. Joel Zonszein, a professor of clinical medicine at the Albert Einstein College of Medicine's Clinical Diabetes Center at Montefiore Medical Center in New York City, said for 40 to 50 years it has been proposed that these viruses may trigger type 1 diabetes.

"There is an association," he said. "It doesn't show a cause-and-effect; it shows an association. Maybe patients with type 1 diabetes are more susceptible to get these enteroviruses."

"It's a good reminder that we don't know the causes of type 1 diabetes," he added.

Type 1 diabetes occurs when the body cannot produce insulin, which is essential in metabolizing sugar. The resulting extra sugar in the blood can cause serious complications, such as heart disease, kidney disease, loss of sight or limbs and an early death. The condition is controlled with doses of insulin and a diet that keep blood sugar levels in normal ranges.

In Type 2 diabetes, which is far more common, the body produces insulin but doesn't utilize it properly. Unlike type 1 diabetes, type 2 is linked to overeating and under-exercising.

More information

For more on type 1 diabetes, visit the U.S. National Library of Medicine.

SOURCES: Maria Craig, M.B.B.S., Ph.D., associate professor, Children's Hospital at Westmead, Institute of Endocrinology and Diabetes, Sydney, Australia; Didier Hober, M.D., Ph.D., professor, virology, University Lille, Lille, France; Joel Zonszein, M.D., professor, clinical medicine, Albert Einstein College of Medicine, Clinical Diabetes Center, Montefiore Medical Center, New York City; Feb. 3, 2011, BMJ, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Flu Viruses Gaining Resistance, Study Confirms
2. Potential new treatment for deadly nipah and hendra viruses identified by Weill Cornell researchers
3. Targeting hit-and-run cancer viruses
4. Researchers find function of proteins that can enhance the progression of viruses and cancer cells
5. To attack H1N1, other flu viruses, gold nanorods deliver potent payload
6. Mount Sinai discovers bone marrow plays critical role in enhancing immune response to viruses
7. Oncolytic viruses mediating anti-tumor immunity in human cancer patients
8. Mild-mannered metabolic helper rushes to fight invading viruses, researchers report
9. Oncos Therapeutics raises €4 million ($5.3 million) to develop oncolytic viruses into cancer treatment
10. UBC graduate student finds a start/stop switch for retroviruses
11. New Study: Improved Immune System with Gene-Eden, a Natural Antiviral Supplement that Targets Chronic Viruses
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cold Viruses Appear Linked to Type 1 Diabetes  
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics ... PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... of Morris F. Collen, a pioneer in the field of medical informatics, this prestigious ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... system that we intend to develop to enable prevention of a major side ... severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017  Eli Lilly and Company (NYSE: ... for the third quarter of 2017 on Tuesday, October ... on that day with the investment community and media ... The conference call will begin at 9 a.m. Eastern ... a live webcast of the conference call through a ...
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host ... webcast on Friday, November 3, 2017, beginning at 7:00 ... approximately 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... performance and guidance for 2018, Hill-Rom executives will also ... performance, and long-range financial outlook through 2020. ...
Breaking Medicine Technology: