Navigation Links
Cold, Flu or Pneumonia? Answer May Lie in Blood Test
Date:8/6/2009

Gene signature detects differences in viral, bacterial infections, study finds

THURSDAY, Aug. 6 (HealthDay News) -- A genomic "signature" in blood appears able to identify people who've been exposed to common upper respiratory viruses, such as the cold or flu, even before symptoms develop.

In a study involving 60 healthy volunteers who were infected with either a live cold virus, respiratory syncytial virus or influenza A virus, the researchers identified changes in 30 genes that are activated as the body responds to infection.

The genomic signature is strong enough to reveal whether the infection is viral or bacterial and can identify who has a viral infection and who does not, according to the study.

The body's immune system responds quickly and in a specific way when exposed to a virus as opposed to bacteria, explained the study's lead author, Dr. Aimee Zaas, an infectious diseases specialist at Duke University in Durham, N.C.

"A detailed reading of that response, using gene expression data, reveals what type of pathogen the person is reacting to," Zaas explained in a news release from the university.

The study, in the August issue of Cell Host & Microbe, could lead to changes in the way doctors care for people who develop upper respiratory infections. Cold, flu and pneumonia symptoms are similar, and doctors can't confirm what a patient has without the results of laboratory tests, a process that can take days.

"Until results are in, treatment is a best guess. Knowing exactly which pathogen is involved is important because it affects the urgency of response and the type of treatment," senior author Dr. Geoffrey Ginsburg, director of Duke's Center for Genomic Medicine, said in the news release.

"This [new] approach could lead to more precise, informed and tailored therapy -- essentially, personalized care for infectious disease," he said. "That's better for the patient and better for public health in general."

More information

The U.S. Centers for Disease Control and Prevention has more about influenza and other respiratory viruses.



-- Robert Preidt



SOURCE: Duke University, news release, Aug. 6, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Clean Hands are Key to Fighting Cold, Flu Germs
2. Winters Cold, Summers Heat Take a Toll
3. The Philadelphia Walk Now for Autism Expected to Draw 10,000 Walkers and Raise $1 Million to Help Find Answers About the Nations Fastest-Growing Developmental Disorder
4. Experts Offer Answers on Colonoscopy Options
5. Alma Lasers Answers Lumenis Complaint
6. Childrens Miracle Network Hospital Doctors On Call to Answer Questions About MRSA Infection
7. Answers.com Adds HealthiNation Video Content to Answer Engine(TM)
8. Researchers hope to provide chronic fatigue syndrome answers
9. New research tools are too complex for easy answers, researchers say
10. New DuPont(TM) Agility(TM) SG Herbicide Offers Wheat Growers Answers to Changing Weed Control Needs
11. Answering Bush SOTU Retirement Reform Challenge, Long Term Care Profession Urges Congress to Enact Bold Reform of Long Term and Post Acute Care Delivery Systems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cold, Flu or Pneumonia? Answer May Lie in Blood Test
(Date:10/13/2017)... , ... October 13, 2017 , ... The American Board ... become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon ... beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice ... of cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU ...
(Date:10/13/2017)... SAN LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... with Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for ... mean is the 90-day elimination period, when the family pays for care, is often ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... for their devotion to personalized service, SMP Pharmacy Solutions announces ... the South Florida Business Journal,s 50 Fastest-Growing Companies, and listed ... national specialty pharmacy has found its niche.  To that end, ... honored by SFBJ as the 2017 Power Leader in Health ... his award in October, Bardisa said of the three achievements, ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: