Navigation Links
Cognitive problems common among non-demented elderly
Date:2/6/2012

Both subjective and objective cognitive impairment are highly common among non-demented elderly Swedes, with an overall prevalence of 39 percent and 25 percent respectively, according to a nationwide twin study by researchers at the Aging Research Center of Karolinska Institutet, Sweden. The study confirms higher education as a major protective factor and stresses the importance of environmental aspects over genes in mild cognitive disorders in old age.

In the current study, which is published in the Journal of Alzheimer's Disease, the researchers investigated the distribution and heritability of subjective and objective cognitive impairment in the population by using data from 11,926 twins aged 65 and above in the Swedish Twin Registry. Objective cognitive impairment involves a reduced performance on tests measuring different cognitive abilities, such as memory and attention, while subjective cognitive impairment involves the same type of problems but experienced only at the subjective level. The researchers then found, that together subjective and objective cognitive impairment affect the majority of non-demented Swedish elderly (joint prevalence 64 percent), suggesting that mild cognitive disorders may represent a major public health concern even in the absence of dementia.

The study also highlights that subjective and objective cognitive impairment has distinct socio-demographic profiles. Specifically, when compared with people with objective cognitive impairment, elderly with subjective complaints only were more educated, more likely to be married, and to have higher socio-economic status pointing to a possible protective effect of this favorable life conditions. Co-twin control analysis showed that the detrimental effect of lower educational level on cognitive functioning is largely independent by genetic background and early life environment.

"This underlies the relevance of adult life educational achievements for preserved cognitive functioning in older life", says Dr Barbara Caracciolo, who led the study at the Aging Research Center in Stockholm.

Regarding the heritability of subjective and objective cognitive impairment, the researchers observed concordance rates of 63 percent and 52 percent in monozygotic twins, 63 percent and 50 percent in dizygotic same-sex twins, and 42 percent and 29 percent in dizygotic unlike-sex twins. The lack of substantial differences in concordance rates between genetically identical (monozygotic) and or non-identical (dizygotic) twins suggests that environmental influences rather than genetic background play the major role in the occurrence of mild cognitive disorders in non-demented elderly.


'/>"/>

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet
Source:Eurekalert

Related medicine news :

1. Drug May Ease Cognitive Effects of Huntingtons
2. Cognitive Skills May Shrink With Tamoxifen
3. Overweight middle-aged adults at greater risk for cognitive decline in later life
4. Chronic Back Pain Soothed by Cognitive Behavioral Therapy
5. Predisposing factors for conversion of mild cognitive impairment to AD identified
6. New Study Finds Cholesterol-Related Gene Associated with Mild Cognitive Impairment, a Precursor of Alzheimer's Disease
7. HAPPYneuron Launches 'Vital' Brain Gym: Cognitive Exercises within SCAN Health Plan's Mobile Resource Center for Seniors
8. Mouli Cohen On Technology For Seniors' Cognitive Care
9. Childrens cognitive ability can be affected by mothers exposure to urban air pollutants
10. Self-Psychology Allows You to Carry A Cognitive Behavioral Therapist On Your iPhone
11. NIH awards $2.7-million grant to Kent State to study cognitive impairment in heart failure patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2017)... ... January 22, 2017 , ... "Photo Cloud allows FCPX ... a beautiful 3D slideshow with complete ease," said Christina Austin - CEO of Pixel ... place in the FCPX timeline. Presets include scenes with one, three, four ...
(Date:1/21/2017)... ... , ... Caronlab Australia, an Australian company known for health and beauty products ... SC, where it benefited from outstanding meetings with major retail buyers. , Caron Labs ... At this trade show, the company had the chance to demonstrate its products and ...
(Date:1/21/2017)... ... ... perfect set of tools for video editors that want to create the illusion of rack ... of Pixel Film Studios. , Video editors using ProDOF can add realistic depth of ... from one area into the next. ProDOF comes with 0.5 second, 1.0 second, 1.5 ...
(Date:1/21/2017)... SAINT- MALO, FRANCE (PRWEB) , ... January 21, 2017 , ... ... heart of the Indian Ocean, isolated from the rest of the world with ZANZIBAR ... of East Africa, Phytocéane used key ingredients, Virgin Coconut Oil and moisturizing vegetal coral ...
(Date:1/21/2017)... Rosa, CA (PRWEB) , ... January 21, 2017 ... ... announce that Redwood Family Dermatology has recently joined their multi-specialty medical ... a full range of cosmetic services. , “We’re excited to add this excellent ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 19, 2017 Report Details ... Alzheimer,s Disease ... Companies – our new study reveals trends, R&D progress, ... events affecting the Alzheimer,s disease therapeutics and diagnostics market. ... key questions: - How is the Alzheimer,s disease therapeutics ...
(Date:1/19/2017)... ATLANTIC CITY, N.J. , Jan. 19, 2017 /PRNewswire/ ... paying over $100 for their medication when a pharmacy ... the same exact prescription.  To alleviate this problem ... doctors and patients to see exactly how much their ... Comparison Shopping Made Easy ...
(Date:1/19/2017)... LONDON , January 19, 2017 Incretin ... Sympathomimetics and Others The global anti-obesity drugs ... the first half of the forecast period and CAGR of 38.7% ... expected to grow at a CAGR of 32.8% from 2016 to ... million in 2021, and $24,063 million in 2027. ...
Breaking Medicine Technology: