Navigation Links
Cognitive impairment seen in preschool children with epilepsy
Date:6/2/2011

A recent study has shown that cognitive impairment is evident early on in preschool children with epilepsy, consistent with results of similar studies in older children. Age of onset of first seizure is a significant predictor of cognitive impairment according to this studythe first to evaluate cognitive impairment in children age three to six. The report is available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE).

Epilepsy is characterized by recurrent seizures that range from mild staring spells to major convulsions, and frequently develops in early childhood. Studies have found that in the U.S. alone there are more than 325,000 children under the age of 15 who are diagnosed with epilepsy, with 45,000 new cases diagnosed each year. Medical evidence further suggests that early onset of seizures is a significant factor contributing to cognitive impairment in children.

For the present study, researchers reviewed medical data and psychological evaluations for 64 preschool children (3 to 6.11 years old) with active epilepsy in order to determine the frequency of cognitive impairment and the epilepsy-related factors contributing to the impairment. Children in the study group had a mean age of five, with seizure onset between 0 and 75 months. "Our study is the first to examine cognitive performance in preschool children with epilepsy," said lead researcher Kati Rantanen, a PhD candidate at the University of Tampere in Finland.

The study showed that the prevalence of epilepsy was roughly 3 per 1,000 children, which is consistent with prior studies in Finland and other developed countries. The team identified 27 children with focal seizures, 31 with generalized seizures, and 6 with unclassified seizure types. More than half of the children (64%) were receiving monotherapy of an anti-epileptic drug for seizure control. The seizures were well-controlled in 37% of children, partially controlled in 16%, and poorly controlled in the remaining 47% of participants.

Researchers determined cognitive function based on psychological evaluation, parental reports, and observations from daycare. The intelligence quotient (IQ) was used to measure cognitive function; children were classified as having normal IQ (IQ over 70) or with mild (50-69), moderate (35-49), or profound (less than 34) intellectual disability. In the preschool cohort, 50% of the children displayed normal cognitive function, 22% had mild cognitive impairment, and 28% showed moderate to severe intellectual disability.

The study found that early onset epilepsy is a risk factor for cognitive impairment. The authors caution that lower (IQ) test scores in young children with epilepsy may be partly a reflection of development delay rather than mental disability. "Early intervention programs may help to improve cognitive and psychological outcomes in preschoolers with epilepsy," Rantanen concluded. "Further prospective research is needed to explore the developmental course of children with epilepsy."


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. U.S. Southeast Stroke Belt Also Shows Higher Rates of Cognitive Decline
2. Cognitive decline incidence higher in Southern stroke belt
3. Older Caregivers at Greater Risk for Cognitive Decline
4. PET-CT exams help identify cognitive reserve in early-onset Alzheimers disease
5. Adverse changes in sleep duration are associated with lower cognitive scores in middle-aged adults
6. Higher levels of social activity decrease the risk of cognitive decline
7. Prenatal exposure to common insecticide linked to decreases in cognitive functioning at age 7
8. Poverty Can Hinder a Childs Cognitive Development, Study Says
9. A screening test for cognitive therapy?
10. Fatigue and sleep woes worsen neurocognitive problems in childhood cancer survivors
11. Sleep issues contribute to cognitive problems in childhood cancer survivors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... ... 25, 2016 , ... Dr. Calvin Johnson has dedicated his ... implemented orthobiologic procedures as a method for treating his patients. The procedure is ... to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to help ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... LAS VEGAS , June 26, 2016 ... movement to value-based care operating models within the health ... that enable greater financial efficiency , Deloitte offers ... address the key business issues impacting efficient cost optimization: ... alignment , These services facilitate better outcomes and ...
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
Breaking Medicine Technology: