Navigation Links
Cognitive decline incidence higher in Southern stroke belt
Date:5/26/2011

New research shows that residents of the Stroke Belta southern portion of the U.S. with significantly elevated stroke morality ratealso have a greater incidence of cognitive decline than other regions of the country. Researchers believe shared risk factors among members of this population are to blame. Results of this study, funded by the National Institute of Neurological Disorders and Stroke (NINDS), are published in Annals of Neurology, a journal of the American Neurological Association.

In 1965 the Stroke Belt first appeared in medical literature to describe the southeastern region of the U.S. where stroke mortality rates were 50% higher than the remaining U.S. regions. According to the Centers for Disease Control and Prevention (CDC) age-adjusted annual rates of stroke mortality among adults 35 and older in the eight Stroke Belt states (Alabama, Arkansas, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, and Tennessee) were on average, 125 per 100,000 individuals, compared to 96 per 100,000 Americans in the remaining 40 contiguous states and the District of Columbia (2000-2006).

The Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, led by Principal Investigator George Howard, DrPH, recruited over 30,000 U.S. adults aged 45 or older from 2003 through 2007 and is following them for stroke and cognitive decline. REGARDS participants included 56% from the Stroke Belt states and 44% from the remaining states in the continental U.S. including D.C. which researchers collectively termed "non-Belt" states. For their report on cognitive decline, the investigators included 23,913 REGARDS participants, made up only of African Americans (38%) and European Americans (62%) who reported no history of stroke at baseline and had normal cognitive status at the first assessment.

"Our study is the first to document higher incidence of cognitive impairment in the Stroke Belt compared to remaining U.S. regions," said Virginia Wadley, Ph.D., Associate Professor of Medicine at the University of Alabama at Birmingham. Researchers assessed brain function using the Six-item Screener (SIS)a test of global cognitive function that includes item recall and temporal orientation. SIS scores range from 0 to 6 with a score of 4 or less representing cognitive impairment.

Results indicate that 8.1% of participants showed cognitive impairment at their most recent assessment, over a mean of 4.1 years following the initial assessment. Stroke Belt residents had a greater likelihood of cognitive impairment than non-Belt residents (odds ratio=1.18); all demographic factors and time independently predicted impairment. Risk of cognitive impairment was 18% higher in residents of the Stroke Belt than in those living in non-Belt states after adjusting for the influences of age, sex, race, and education level.

The research team suggests that future studies should examine the impact of migration patterns, urban versus rural residence, socioeconomic factors, and educational quality on cognitive decline. "Investigating regional patterns that contribute to modifiable risk factors affecting cognitive decline will allow for prevention and intervention efforts that are geographically concentrated," concluded Dr. Wadley. "Information obtained from the REGARDS study can be used to develop services for older Americans at both local and national levels to improve outcomes for those most vulnerable to diminished cognitive function."


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Older Caregivers at Greater Risk for Cognitive Decline
2. PET-CT exams help identify cognitive reserve in early-onset Alzheimers disease
3. Adverse changes in sleep duration are associated with lower cognitive scores in middle-aged adults
4. Higher levels of social activity decrease the risk of cognitive decline
5. Prenatal exposure to common insecticide linked to decreases in cognitive functioning at age 7
6. Poverty Can Hinder a Childs Cognitive Development, Study Says
7. A screening test for cognitive therapy?
8. Fatigue and sleep woes worsen neurocognitive problems in childhood cancer survivors
9. Sleep issues contribute to cognitive problems in childhood cancer survivors
10. Alzheimers-like brain changes found in cognitively normal elders with amyloid plaques
11. Indications of Alzheimers disease may be evident decades before first signs of cognitive impairment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... May 27, 2016 , ... Beleza Medspa has initiated a ... This is the first time that Coolsculpting is being used for for more ... months to ensure they meet the prescribed body-fat standard, measured by the circumference-based tape ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and employees in the ... courtesy of leaders in the nursing and health care industry. It also provides insight ... Abilene Christian University. , As the nursing industry is coming out of one ...
(Date:5/27/2016)... ... May 27, 2016 , ... With a team ... and food industries. Aside from its GMP accreditation, Validation Center is also a ... certified products, services and staff. , Validation Center is ISO17025 accredited and only ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways ... and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. ... say grilling is their favorite way to cook a hot dog, far outpacing other ...
(Date:5/26/2016)... ... May 26, 2016 , ... Cabot Corporation, Pfizer, and ... according to court documents and SEC filings. A jury has returned a ... American Optical Corporation, Case No. BC588866, Los Angeles County, California. The jury awarded ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... , May 26, 2016 Since ... matured into an essential life science tool for conducting ... applications. BCC Research reveals in its new report that ... growth phase, one powered by a range of new ...      (Logo: http://photos.prnewswire.com/prnh/20140723/694805 ) , ...
(Date:5/25/2016)... GERMANTOWN, Maryland , May 25, 2016 ... bedient dringenden Bedarf zur ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt ... und Entwicklungsvereinbarung mit Therawis Diagnostics GmbH zur Entwicklung ... zu sein. Ein erstes Projekt wird die Entwicklung ...
(Date:5/25/2016)... , May 25, 2016  According to Kalorama ... $381 billion in 2015.  Though these are challenging ... of opportunity for success for companies that remain ... search of new growth prospects medical device companies ... research and development (R&D) than do companies in ...
Breaking Medicine Technology: