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Cognitive decline incidence higher in Southern stroke belt
Date:5/26/2011

New research shows that residents of the Stroke Belta southern portion of the U.S. with significantly elevated stroke morality ratealso have a greater incidence of cognitive decline than other regions of the country. Researchers believe shared risk factors among members of this population are to blame. Results of this study, funded by the National Institute of Neurological Disorders and Stroke (NINDS), are published in Annals of Neurology, a journal of the American Neurological Association.

In 1965 the Stroke Belt first appeared in medical literature to describe the southeastern region of the U.S. where stroke mortality rates were 50% higher than the remaining U.S. regions. According to the Centers for Disease Control and Prevention (CDC) age-adjusted annual rates of stroke mortality among adults 35 and older in the eight Stroke Belt states (Alabama, Arkansas, Georgia, Louisiana, Mississippi, North Carolina, South Carolina, and Tennessee) were on average, 125 per 100,000 individuals, compared to 96 per 100,000 Americans in the remaining 40 contiguous states and the District of Columbia (2000-2006).

The Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, led by Principal Investigator George Howard, DrPH, recruited over 30,000 U.S. adults aged 45 or older from 2003 through 2007 and is following them for stroke and cognitive decline. REGARDS participants included 56% from the Stroke Belt states and 44% from the remaining states in the continental U.S. including D.C. which researchers collectively termed "non-Belt" states. For their report on cognitive decline, the investigators included 23,913 REGARDS participants, made up only of African Americans (38%) and European Americans (62%) who reported no history of stroke at baseline and had normal cognitive status at the first assessment.

"Our study is the first to document higher incidence of cognitive impairment in the Stroke Belt compared to remaining U.S. re
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Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

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