Navigation Links
Cogentus Pharmaceuticals Names Scientific Steering Committee for Global Phase 3 Clinical Program
Date:2/8/2008

ficacy and safety of Cogentus's lead product, CGT-2168, which combines the antiplatelet medicine clopidogrel (currently marketed by Bristol-Myers Squibb Co. and Sanofi-Aventis as Plavix(R)) and a gastroprotectant (omeprazole).

While antiplatelet therapy has been shown to be effective in preventing major cardiovascular events, it is associated with significant gastrointestinal side effects including bleeding, which can interrupt treatment, may require hospitalization or in some cases even result in death. Bleeding from the use of the antiplatelet drugs aspirin and clopidogrel has been shown respectively to be the third and fourth most common causes of U.S. emergency room visits by older adults experiencing adverse drug events.

"It is critical that patients are able to remain on treatment," Dr. Goldsmith said. A new analysis published in this week's Journal of the American Medical Association showed that patients with acute coronary syndrome who stopped taking Plavix nearly doubled their risk of heart attack or death within the first 90 days following the end of treatment.

CGT-2168 is designed to maintain full protective cardiovascular benefits while reducing the potentially serious gastrointestinal side effects commonly associated with antiplatelet therapy. Early results with CGT-2168 show excellent absorption and metabolism of clopidogrel that are unaffected by the delayed-release omeprazole within this combination product. Cogentus believes these findings suggest the novel formulation avoids a drug-drug interaction that has been reported when the individual marketed drugs are co-administered.

"It is important for patients to receive the full cardiovascular effect of dual antiplatelet therapy while reducing gastrointestinal side effects," said Steering Committee member Dr. Marc Cohen. "The COGENT program is evaluating whether CGT-2168 will maintain the cardiovascular benefits of treatment while minimizing bleeding."

"We believe CGT
'/>"/>

SOURCE Cogentus Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Cogentus Pharmaceuticals Completes $62.5 Million Private Financing
2. Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference
3. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
4. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
5. Idenix Pharmaceuticals to Present at Two Upcoming Investor Conferences
6. Vista Partners Updates Coverage on Tapestry Pharmaceuticals
7. Transcept Pharmaceuticals, Inc. to Present at UBS 2007 Global Life Sciences Conference
8. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc.
9. Amylin Pharmaceuticals to Webcast Corporate Overview During 43rd Annual Meeting of the European Association for the Study of Diabetes
10. Major Pharma Clinical Case Studies From Amgen, AstraZeneca, GSK, Intermune, Cephalon Inc, Sunesis Pharmaceuticals and Dartmouth Medical School During Fall Clinical Focused Programs
11. Provectus Pharmaceuticals, Inc. releases summary results of phase 1 metastatic melanoma study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... November 22, 2014 Discount-Dress.com is ... of the firm is to increase the company’s online market ... a new selection of bridesmaid dresses and announced a bridesmaid ... is valid until Dec. 30, 2014. All the dresses from ... inexpensive. , In fact, Discount-Dress.com is very good at ...
(Date:11/22/2014)... New York, New York (PRWEB) November 22, 2014 ... use of power morcellators ( http://www.morcellatorlawsuit2015.com ) in ... than 450 new signatures since the end of October, ... people had signed the petition as of November 21st, ... October 31st, when 86,042 supporters had signed on to ...
(Date:11/22/2014)... 2014 Lipitor lawsuits ( http://www.lipitorlawsuitcenter.com/ ) ... allegedly developed Type 2 diabetes due to its use ... now underway in U.S. District Court, District of South ... the litigation will convene its next Status Conference on ... Lead Counsel for Plaintiffs and Defendants to meet and ...
(Date:11/22/2014)... Forbes Living TV and featured ... that Ashley Lombardo and friend Candy Sherman are the ... Lombardo entered friend Candy Sherman to receive a generous ... her friend is courageously battling lung cancer and raising ... medical bills piling up and the constant struggle to ...
(Date:11/22/2014)... Developers and plugin specialist of Final Cut ... 3D Model bringing the impossible to FCPX from ... add obj files to FCPX enabling 3d Model editing,” said ... between professional and armature, FCPX 3D Model is a definite ... Final Cut Pro X users to upload and control 3D ...
Breaking Medicine News(10 mins):Health News:Bridesmaid Dresses Introduced by Famous Company Discount-Dress.com For The New Year 2015 2Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 2Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 3Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 4Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 2Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 3Health News:Forbes Living TV Announces Winner of Thanksgiving #PayItForward Contest 2Health News:Pixel Film Studios released FCPX 3D Model plugin Exclusively for Final Cut Pro X 2
... Government plans to hasten patient treatment has included bestowing ... drugs//. ,Under this plan, nurses and pharmacists ... for common illnesses that range from acne to tonsillitis. ... clinics and will soon be able to prescribe drugs ...
... industry a panel comprising European experts recommended Sanofi-Aventis's anti-obesity pill ... news was brought to light by the company itself. ... block a pleasure centre and so fight obesity. People on ... with eating. ,Data from a trial involving more ...
... College of Nursing congress last week shouted at Patricia Hewitt ... their hostility to a government which was a great ally ... and what are they furious about? There are 70,000 nurses ... has also risen considerably over the past three years. Les ...
... in the May issue of the journal Medical Care say ... alright to discuss religion with their patients.// However, only three ... beliefs and only half of them bother to query a ... ten physicians routinely mentions his or her religious beliefs and ...
... the rain, there seems to be enough shine, making Washington, ... to the Environmental// Protection Agency. , ,The ... to schools that comprise of 40 activity cards and a ... the sun's UV rays. , ,Demonstrators apply ...
... occur in children whose mothers report difficulties with substance ... delivery, reports a study published in the Archives of ... / mood disorders, smoking, maternal drinking, substance or drug ... that can contribute to behavior problems in children. Although ...
Cached Medicine News:Health News:Doctors' Response To Patients' Religious Beliefs Can Vary 2Health News:Doctors' Response To Patients' Religious Beliefs Can Vary 3Health News:Maternal Difficulties Increase Risk of Behavior Problems in Children 2
(Date:11/21/2014)...   Wellcentive , the industry leader in ... announced today being named one of the four ... .  Sponsored by Intel, the world leader in ... recognizes companies developing leading-edge technology and unique approaches ... Wellcentive,s Mason Beard , senior ...
(Date:11/18/2014)... Nov. 18, 2014  NxStage ® Medical ... manufacturer of innovative dialysis products , today ... dialyzer for the in-center, hemodialysis market.  Streamline ... is designed to reduce the amount of labor ... number of touch point contamination sites.  The dialyzer ...
(Date:11/18/2014)... 18, 2014 Breast cancer will interrupt ... year who get a new diagnosis. The Commission ... for case managers to help those diagnosed with ... myriad physical, emotional and financial decisions that come ... no cost via the Commission,s online knowledge resource, ...
Breaking Medicine Technology:Wellcentive Named Finalist for 2014 Intel Innovation Award 2Wellcentive Named Finalist for 2014 Intel Innovation Award 3NxStage Launches New Streamline Express Dialyzer With Pre-attached Blood Tubing Set 2New Breast Cancer Resources: Commission For Case Manager Certification Adds Specialty Tools to Case Management Body of Knowledge Online Learning Center 2
... HeartSine ® Technologies, Inc., a world leader in ... work together with the Newtown Township Police Department (Pennsylvania) ... AED (Automated External Defibrillator) in every squad car. ... donated the HeartSine samaritan ® PAD 300P Public ...
... Electronics (AEX: PHI, NYSE: PHG ) today announced ... at four customer sites in North America, bringing clinicians uncompromised ... on display at the 97th annual meeting of the Radiological ... Mammography is the primary tool used to aid ...
Cached Medicine Technology:HeartSine® Technologies and the Newtown Township Police Join Forces 2HeartSine® Technologies and the Newtown Township Police Join Forces 3Philips MicroDose Next Generation Mammography Solution Gains Traction with First North American Customers, Enabling Excellent Image Quality at a Low Radiation Dose 2Philips MicroDose Next Generation Mammography Solution Gains Traction with First North American Customers, Enabling Excellent Image Quality at a Low Radiation Dose 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: